Development Level

Tbio 30 | 11,445
Tchem 13 | 1,598
Tclin 7 | 613

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal retina morphology 2 | 71
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
hypoactivity 2 | 132
increased neutrophil cell numb... 2 | 46
preweaning lethality, incomple... 2 | 499
short tibia 2 | 97
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal femur morphology 1 | 14
abnormal head morphology 1 | 10
abnormal lens morphology 1 | 81
abnormal rib morphology 1 | 10
abnormal sleep behavior 1 | 70
abnormal startle reflex 1 | 15
cataract 1 | 92
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating lipase l... 1 | 3
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased coping response 1 | 8
decreased fasted circulating g... 1 | 65
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased spleen weight 1 | 10
decreased total body fat amoun... 1 | 207
enlarged kidney 1 | 14
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating potassiu... 1 | 29
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 39
increased hemoglobin content 1 | 45
increased monocyte cell number 1 | 63
increased spleen weight 1 | 10
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
mammalian phenotype 1 | 17
prenatal lethality 1 | 28

Disease

Carcinoma 40 | 11,493
ovarian cancer 36 | 8,520
Cancer 35 | 2,499
osteosarcoma 30 | 7,950
lung cancer 24 | 4,740
glioblastoma 23 | 5,792
medulloblastoma, large-cell 23 | 6,241
psoriasis 21 | 6,694
Kidney cancer 20 | 2,613
atypical teratoid / rhabdoid tumor 20 | 5,112
Astrocytoma, Pilocytic 19 | 3,081
ependymoma 18 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
Schizophrenia 16 | 1,160
malignant mesothelioma 16 | 3,232
Breast cancer 15 | 3,578
invasive ductal carcinoma 15 | 2,951
non-small cell lung cancer 15 | 2,890
group 4 medulloblastoma 13 | 1,855
interstitial cystitis 13 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
oligodendroglioma 13 | 2,850
pancreatic cancer 13 | 2,398
pituitary cancer 13 | 1,972
primitive neuroectodermal tumor 13 | 3,035
breast carcinoma 12 | 1,638
diabetes mellitus 12 | 1,728
Alzheimer's disease 11 | 658
Breast Neoplasms 11 | 445
Carcinoma, Hepatocellular 10 | 228
Liver carcinoma 10 | 240
Mammary Neoplasms 10 | 425
Neoplasm Invasiveness 10 | 161
Stomach Neoplasms 10 | 300
adult high grade glioma 10 | 3,801
astrocytoma 10 | 1,146
ductal carcinoma in situ 10 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
lung adenocarcinoma 10 | 2,716
pediatric high grade glioma 10 | 1,064
tuberculosis 10 | 2,010
ulcerative colitis 10 | 1,819
Pick disease 9 | 1,894
astrocytic glioma 9 | 2,597
cystic fibrosis 9 | 1,696
group 3 medulloblastoma 9 | 4,104
juvenile dermatomyositis 9 | 1,187
subependymal giant cell astrocytoma 9 | 2,287
Autistic Disorder 8 | 364
Autosomal recessive predisposition 8 | 1,442
Colorectal Neoplasms 8 | 243
Intellectual disability 8 | 1,016
Neoplasm Metastasis 8 | 168
lung carcinoma 8 | 2,843
Adenoma 7 | 167
Bipolar Disorder 7 | 666
Muscle hypotonia 7 | 571
Obesity 7 | 678
Status Epilepticus 7 | 98
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
Adenocarcinoma 6 | 122
Carcinoma, Squamous Cell 6 | 110
Disease Progression 6 | 136
Downward slant of palpebral fissure 6 | 158
Dull intelligence 6 | 645
Failure to gain weight 6 | 365
Immune system cancer 6 | 140
Liver cancer 6 | 604
Low intelligence 6 | 645
Low set ears 6 | 181
Lymphoid leukemia 6 | 160
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Nerve Degeneration 6 | 121
Pediatric failure to thrive 6 | 365
Poor school performance 6 | 645
Prostatic Neoplasms 6 | 495
Short stature 6 | 531
Weight decreased 6 | 103
acute quadriplegic myopathy 6 | 1,158
adrenocortical carcinoma 6 | 1,428
esophageal adenocarcinoma 6 | 737
primary pancreatic ductal adenocarcinoma 6 | 1,109
Cardiovascular Diseases 5 | 59
Cerebrovascular disease 5 | 238
Colonic Neoplasms 5 | 142
Duchenne muscular dystrophy 5 | 601
Endometrial cancer 5 | 311
Epilepsy 5 | 792
Huntington's disease 5 | 76
Kidney disease 5 | 430
Lung Neoplasms 5 | 232
Major Depressive Disorder 5 | 301
Melanoma 5 | 711
Multiple myeloma 5 | 1,332
Parkinson's disease 5 | 392
Unipolar Depression 5 | 250
colon cancer 5 | 1,478
hepatocellular carcinoma 5 | 547
primary Sjogren syndrome 5 | 735

Tissue

Blood and immune system 49 | 16,909
Digestive Tract 49 | 17,369
Endocrine System 49 | 18,159
Female tissues 49 | 17,400
Liver and Pancreas 49 | 16,750
Male tissues 49 | 17,142
Nervous System 49 | 16,725
Respiratory system 49 | 16,393
Skin and soft tissues 49 | 17,230
Urinary Tract 48 | 16,678
Cardiovascular System 47 | 15,192

Target Family

Non-IDG 24 | 12,091
Enzyme 14 | 4,145
Kinase 10 | 634
Epigenetic 1 | 242
Transcription Factor 1 | 1,400

PathwayCommons: pid Pathway

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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tyrosine-protein kinase Fer FER Tchem Kinase -1.86307 55.4 414
GTPase HRas HRAS Tchem Enzyme -4.01300 9975.8 492
Ras-related protein Rab-7a RAB7A Tbio Enzyme -2.66545 435.4 248
Nucleoside diphosphate kinase A NME1 Tbio Kinase -2.99077 863.1 945
Desmoplakin DSP Tbio Non-IDG -2.95735 853.9 198
Cell division control protein 42 homolog CDC42 Tchem Enzyme -3.37283 2188.5 380
Cadherin-2 CDH2 Tbio Non-IDG -3.19431 1382.9 993
Meprin A subunit beta MEP1B Tbio Non-IDG -1.52523 33.3 36
Hepatocyte growth factor receptor MET Tclin Kinase -3.32232 2013.7 1982
Cadherin-1 CDH1 Tbio Non-IDG -3.85201 6324.3 1880