Development Level

Tbio 25 | 11,445
Tchem 12 | 1,598
Tclin 4 | 613
Tdark 1 | 6,588

IMPC Phenotype

decreased total body fat amoun... 2 | 207
impaired glucose tolerance 2 | 75
increased circulating creatini... 2 | 38
preweaning lethality, complete... 2 | 979
abnormal bone structure 1 | 187
abnormal femur morphology 1 | 14
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
decreased bone mineral content 1 | 151
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
dilated heart left ventricle 1 | 11
enlarged heart 1 | 210
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating phosphat... 1 | 26
increased circulating triglyce... 1 | 42
increased heart weight 1 | 62
increased large unstained cell... 1 | 5
increased mean corpuscular hem... 1 | 36
increased neutrophil cell numb... 1 | 46
increased red blood cell distr... 1 | 34
persistence of hyaloid vascula... 1 | 33
short tibia 1 | 97

Disease

Carcinoma 35 | 11,493
ovarian cancer 29 | 8,520
atypical teratoid / rhabdoid tumor 26 | 5,112
glioblastoma 26 | 5,792
Breast cancer 24 | 3,578
psoriasis 24 | 6,694
lung cancer 23 | 4,740
non-small cell lung cancer 23 | 2,890
lung adenocarcinoma 22 | 2,716
medulloblastoma, large-cell 22 | 6,241
Astrocytoma, Pilocytic 21 | 3,081
Kidney cancer 21 | 2,613
ependymoma 21 | 4,679
malignant mesothelioma 20 | 3,232
pancreatic cancer 20 | 2,398
interstitial cystitis 19 | 2,312
Cancer 18 | 2,499
osteosarcoma 18 | 7,950
adult high grade glioma 17 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,989
invasive ductal carcinoma 17 | 2,951
Autosomal recessive predisposition 16 | 1,442
Short stature 16 | 531
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
ulcerative colitis 16 | 1,819
Liver Cirrhosis, Experimental 15 | 769
breast carcinoma 15 | 1,638
gastric carcinoma 15 | 807
group 3 medulloblastoma 15 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,291
primitive neuroectodermal tumor 15 | 3,035
esophageal adenocarcinoma 14 | 737
pituitary cancer 14 | 1,972
Duchenne muscular dystrophy 13 | 601
Acquired scoliosis 12 | 281
Curvature of spine 12 | 282
cystic fibrosis 12 | 1,696
ductal carcinoma in situ 12 | 1,745
juvenile dermatomyositis 12 | 1,187
lung carcinoma 12 | 2,843
nasopharyngeal carcinoma 12 | 1,058
oligodendroglioma 12 | 2,850
Becker muscular dystrophy 11 | 191
Liver cancer 11 | 604
Skin cancer 11 | 469
autosomal dominant Emery-Dreifuss muscular dystrophy 11 | 510
Degenerative polyarthritis 10 | 115
Kidney disease 10 | 430
Melanoma 10 | 711
Myopia 10 | 176
Neoplasm Invasiveness 10 | 161
diabetes mellitus 10 | 1,728
interstitial lung disease 10 | 298
limb girdle muscular dystrophy 2A 10 | 213
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
subependymal giant cell astrocytoma 10 | 2,287
Abortion, Spontaneous 9 | 109
Cognitive delay 9 | 608
Congenital deafness 9 | 185
Deafness 9 | 198
Global developmental delay 9 | 608
Hearing Loss, Partial 9 | 185
Hyperkyphosis 9 | 111
Hypertensive disease 9 | 292
Kyphosis deformity of spine 9 | 114
Mental and motor retardation 9 | 608
Neoplasm Metastasis 9 | 168
Spontaneous abortion 9 | 113
active Crohn's disease 9 | 922
adrenocortical carcinoma 9 | 1,428
colon cancer 9 | 1,478
cutaneous lupus erythematosus 9 | 1,057
hearing impairment 9 | 199
urothelial carcinoma 9 | 318
Exophthalmos 8 | 112
Hypoplastic mandible condyle 8 | 275
Joint hyperflexibility 8 | 78
Mandibular hypoplasia 8 | 275
Micrognathism 8 | 275
Orbital separation excessive 8 | 244
Osteoporosis 8 | 363
Pectus excavatum 8 | 100
Prominent eyes 8 | 96
Prominent globes 8 | 96
Protruding eyes 8 | 96
Schizophrenia 8 | 1,160
astrocytoma 8 | 1,146
head and neck cancer and chronic obstructive pulmonary disease 8 | 239
Arthritis 7 | 290
Contracture 7 | 96
Contracture of joint 7 | 93
Flexion contracture 7 | 93
Flexion contractures of joints 7 | 93
Liver Cirrhosis 7 | 181
Lung Neoplasms 7 | 232
dermatomyositis 7 | 966
pediatric high grade glioma 7 | 1,064
primary pancreatic ductal adenocarcinoma 7 | 1,109
pterygium 7 | 76
tuberculosis 7 | 2,010

Tissue

Digestive Tract 42 | 17,369
Endocrine System 42 | 18,159
Female tissues 42 | 17,400
Male tissues 42 | 17,142
Skin and soft tissues 42 | 17,230
Blood and immune system 41 | 16,909
Liver and Pancreas 41 | 16,750
Respiratory system 41 | 16,393
Nervous System 40 | 16,725
Urinary Tract 40 | 16,678
Cardiovascular System 39 | 15,192

Target Family

Non-IDG 28 | 12,091
Kinase 8 | 634
Enzyme 6 | 4,145

PathwayCommons: pid Pathway

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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Collagen alpha-2(V) chain COL5A2 Tbio Non-IDG -1.69982 44.6 96
Fibroblast growth factor 19 FGF19 Tbio Non-IDG -2.54882 334.2 305
Collagen alpha-1(IV) chain COL4A1 Tbio Non-IDG -2.28595 186.9 391
Collagen alpha-3(VI) chain COL6A3 Tbio Non-IDG -1.79687 61.3 32
Collagen alpha-1(XI) chain COL11A1 Tbio Non-IDG -2.15516 138.4 96
Collagen alpha-1(VI) chain COL6A1 Tbio Non-IDG -2.03348 104.7 204
Collagen alpha-2(VI) chain COL6A2 Tbio Non-IDG -1.80531 59.2 151
Collagen alpha-6(VI) chain COL6A6 Tdark Non-IDG -0.48745 3.28 27
Fibroblast growth factor receptor 3 FGFR3 Tclin Kinase -3.00731 1050.1 479
Fibroblast growth factor 23 FGF23 Tbio Non-IDG -3.19500 1726.4 296