Development Level

Tchem 14 | 1,598
Tbio 12 | 11,445
Tclin 2 | 613

IMPC Phenotype

decreased total body fat amoun... 2 | 207
increased circulating alkaline... 2 | 122
preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal bone structure 1 | 187
abnormal eye morphology 1 | 68
abnormal heart morphology 1 | 162
abnormal skin morphology 1 | 50
anophthalmia 1 | 33
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased circulating creatini... 1 | 39
decreased lean body mass 1 | 135
enlarged heart 1 | 210
increased body length 1 | 32
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating choleste... 1 | 66
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
increased erythrocyte cell num... 1 | 39
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased total body fat amoun... 1 | 134
thrombocytopenia 1 | 56

Disease

Carcinoma 22 | 11,493
ovarian cancer 20 | 8,520
Cancer 18 | 2,499
glioblastoma 18 | 5,792
atypical teratoid / rhabdoid tumor 17 | 5,112
osteosarcoma 15 | 7,950
psoriasis 15 | 6,694
medulloblastoma, large-cell 14 | 6,241
adult high grade glioma 12 | 3,801
lung cancer 11 | 4,740
Astrocytoma, Pilocytic 9 | 3,081
Breast cancer 9 | 3,578
Kidney cancer 9 | 2,613
Schizophrenia 9 | 1,160
ependymoma 9 | 4,679
Kidney disease 8 | 430
group 4 medulloblastoma 8 | 1,855
invasive ductal carcinoma 8 | 2,951
pancreatic cancer 8 | 2,398
Proteinuria 7 | 144
diabetes mellitus 7 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
lung adenocarcinoma 7 | 2,716
non-small cell lung cancer 7 | 2,890
primitive neuroectodermal tumor 7 | 3,035
subependymal giant cell astrocytoma 7 | 2,287
Bipolar Disorder 6 | 666
Depressive disorder 6 | 409
Nephrotic Syndrome 6 | 78
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
malignant mesothelioma 6 | 3,232
Alzheimer's disease 5 | 658
Mental Depression 5 | 333
Stomach Neoplasms 5 | 300
Vascular disease 5 | 319
breast carcinoma 5 | 1,638
ductal carcinoma in situ 5 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
oligodendroglioma 5 | 2,850
spina bifida 5 | 1,074
tuberculosis 5 | 2,010
Albuminuria 4 | 21
Arthritis 4 | 290
Autosomal recessive predisposition 4 | 1,442
Focal glomerulosclerosis 4 | 37
Glomerulosclerosis, Focal Segmental 4 | 28
Heart disease 4 | 306
Hyperglycemia 4 | 137
Hypertension 4 | 396
Inflammatory bowel disease 4 | 151
Parkinson's disease 4 | 392
Prostatic Neoplasms 4 | 495
Rheumatoid arthritis 4 | 1,191
Waldenstrons macroglobulinemia 4 | 765
astrocytic glioma 4 | 2,597
astrocytoma 4 | 1,146
group 3 medulloblastoma 4 | 4,104
interstitial cystitis 4 | 2,312
juvenile dermatomyositis 4 | 1,187
pituitary cancer 4 | 1,972
Asthma 3 | 385
Brain disease 3 | 96
Breast Neoplasms 3 | 445
Carcinoma, Hepatocellular 3 | 228
Cataract 3 | 297
Disease Models, Animal 3 | 155
Dull intelligence 3 | 645
Endometrial cancer 3 | 311
Epilepsy 3 | 792
Hyperalgesia 3 | 83
Hypoplastic mandible condyle 3 | 275
Hypothyroidism 3 | 122
Intellectual disability 3 | 1,016
Lens Opacities 3 | 231
Leukemia 3 | 104
Liver carcinoma 3 | 240
Liver disease 3 | 237
Low intelligence 3 | 645
Lung Neoplasms 3 | 232
Lung disease 3 | 142
Mammary Neoplasms 3 | 425
Mandibular hypoplasia 3 | 275
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Micrognathism 3 | 275
Myopia 3 | 176
Neoplasm Metastasis 3 | 168
Nephroblastoma 3 | 51
Obesity 3 | 678
Pick disease 3 | 1,894
Poor school performance 3 | 645
Reperfusion Injury 3 | 86
Skin cancer 3 | 469
Toxic encephalopathy 3 | 141
acute myeloid leukemia 3 | 783
cystic fibrosis 3 | 1,696
dermatomyositis 3 | 966
fibroadenoma 3 | 559
pancreatic carcinoma 3 | 562
primary pancreatic ductal adenocarcinoma 3 | 1,109

Tissue

Blood and immune system 28 | 16,909
Digestive Tract 28 | 17,369
Endocrine System 28 | 18,159
Nervous System 28 | 16,725
Urinary Tract 28 | 16,678
Female tissues 27 | 17,400
Liver and Pancreas 27 | 16,750
Cardiovascular System 26 | 15,192
Male tissues 26 | 17,142
Respiratory system 26 | 16,393
Skin and soft tissues 26 | 17,230

Target Family

Non-IDG 12 | 12,091
Kinase 11 | 634
Enzyme 2 | 4,145
GPCR 1 | 408
Ion Channel 1 | 344
Transcription Factor 1 | 1,400

PathwayCommons: pid Pathway

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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
CD2-associated protein CD2AP Tbio Non-IDG -3.44533 2735.9 82
Podocin NPHS2 Tbio Non-IDG -2.59327 375.7 96
Dual specificity mitogen-activated protein kinase kinase 4 MAP2K4 Tchem Kinase -2.43646 236.7 998
Proteinase-activated receptor 3 F2RL2 Tbio GPCR -0.33786 2.70 169
Tight junction protein ZO-1 TJP1 Tbio Non-IDG -3.20720 1368.9 292
Nephrin NPHS1 Tbio Non-IDG -3.16031 1396.4 555
Bcl2-associated agonist of cell death BAD Tchem Non-IDG -2.08893 103.4 2565
Short transient receptor potential channel 6 TRPC6 Tchem Ion Channel -2.82303 661.6 320
Protein kinase C iota type PRKCI Tchem Kinase -1.71694 51.2 148
Mitogen-activated protein kinase 10 MAPK10 Tchem Kinase -2.29568 193.3 384