Development Level

Tbio 23 | 11,445
Tchem 13 | 1,598
Tclin 1 | 613

IMPC Phenotype

embryonic lethality prior to t... 2 | 278
abnormal behavior 1 | 298
abnormal embryo size 1 | 220
abnormal femur morphology 1 | 14
abnormal forebrain development 1 | 20
abnormal heart morphology 1 | 162
abnormal hindbrain development 1 | 16
abnormal lens morphology 1 | 81
abnormal neural tube closure 1 | 46
cataract 1 | 92
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased heart left ventricle... 1 | 28
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
dilated heart left ventricle 1 | 11
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased heart weight 1 | 62
increased mean corpuscular hem... 1 | 36
increased or absent threshold ... 1 | 101
male infertility 1 | 123
pale yolk sac 1 | 25
preweaning lethality, complete... 1 | 979
short tibia 1 | 97

Disease

Cancer 30 | 2,499
psoriasis 27 | 6,694
ovarian cancer 26 | 8,520
Carcinoma 25 | 11,493
lung cancer 25 | 4,740
glioblastoma 20 | 5,792
interstitial cystitis 18 | 2,312
malignant mesothelioma 18 | 3,232
non-small cell lung cancer 18 | 2,890
pancreatic cancer 18 | 2,398
ependymoma 17 | 4,679
lung carcinoma 17 | 2,843
Breast cancer 16 | 3,578
adult high grade glioma 16 | 3,801
atypical teratoid / rhabdoid tumor 16 | 5,112
medulloblastoma, large-cell 16 | 6,241
osteosarcoma 16 | 7,950
diabetes mellitus 15 | 1,728
lung adenocarcinoma 15 | 2,716
cystic fibrosis 14 | 1,696
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,291
pituitary cancer 14 | 1,972
Astrocytoma, Pilocytic 13 | 3,081
Kidney disease 13 | 430
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
ulcerative colitis 13 | 1,819
Heart disease 12 | 306
Liver Cirrhosis, Experimental 12 | 769
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
invasive ductal carcinoma 12 | 2,951
Arthritis 11 | 290
Breast Neoplasms 11 | 445
Hypertension 11 | 396
Mammary Neoplasms 11 | 425
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,962
Atherosclerosis 10 | 291
Lung Neoplasms 10 | 232
Neoplasm Invasiveness 10 | 161
Obesity 10 | 678
Prostatic Neoplasms 10 | 495
Schizophrenia 10 | 1,160
Stomach Neoplasms 10 | 300
colon cancer 10 | 1,478
tuberculosis 10 | 2,010
Kidney cancer 9 | 2,613
Liver disease 9 | 237
adrenocortical carcinoma 9 | 1,428
breast carcinoma 9 | 1,638
ductal carcinoma in situ 9 | 1,745
nasopharyngeal carcinoma 9 | 1,058
primitive neuroectodermal tumor 9 | 3,035
Asthma 8 | 385
Atopic dermatitis 8 | 952
Autosomal recessive predisposition 8 | 1,442
Carcinoma, Squamous Cell 8 | 110
Cerebrovascular disease 8 | 238
Coronary artery disease 8 | 268
Hypertensive disease 8 | 292
Lung disease 8 | 142
Osteoporosis 8 | 363
Reperfusion Injury 8 | 86
Squamous cell carcinoma 8 | 129
group 4 medulloblastoma 8 | 1,855
Alzheimer's disease 7 | 658
Anemia 7 | 365
Bipolar Disorder 7 | 666
Carcinoma, Hepatocellular 7 | 228
Hyperglycemia 7 | 137
Inflammation 7 | 120
Liver Cirrhosis 7 | 181
Liver carcinoma 7 | 240
Multiple Sclerosis 7 | 540
Myocardial Infarction 7 | 151
Myocardial Ischemia 7 | 169
Neoplasm Metastasis 7 | 168
active ulcerative colitis 7 | 764
astrocytoma 7 | 1,146
cutaneous lupus erythematosus 7 | 1,057
esophageal adenocarcinoma 7 | 737
group 3 medulloblastoma 7 | 4,104
interstitial lung disease 7 | 298
primary pancreatic ductal adenocarcinoma 7 | 1,109
subependymal giant cell astrocytoma 7 | 2,287
Brain Ischemia 6 | 110
Cell Transformation, Neoplastic 6 | 97
Dental caries 6 | 164
Depressive disorder 6 | 409
Endometriosis 6 | 540
Hypersensitivity reaction type II disease 6 | 253
Major Depressive Disorder 6 | 301
Mental Depression 6 | 333
Neoplastic Cell Transformation 6 | 89
Pulmonary Fibrosis 6 | 106
Pulmonary hypertension 6 | 85
Vascular disease 6 | 319
aldosterone-producing adenoma 6 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
gastric cancer 6 | 459
juvenile dermatomyositis 6 | 1,187
periodontitis 6 | 293

Tissue

Blood and immune system 37 | 16,909
Digestive Tract 37 | 17,369
Female tissues 37 | 17,400
Male tissues 37 | 17,142
Nervous System 37 | 16,725
Respiratory system 37 | 16,393
Skin and soft tissues 37 | 17,230
Urinary Tract 37 | 16,678
Endocrine System 36 | 18,159
Liver and Pancreas 36 | 16,750
Cardiovascular System 34 | 15,192

Target Family

Non-IDG 17 | 12,091
Transcription Factor 12 | 1,400
Enzyme 7 | 4,145
Epigenetic 1 | 242

PathwayCommons: pid Pathway

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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Leukemia inhibitory factor LIF Tbio Non-IDG -2.86943 538.7 413
Gamma-taxilin TXLNG Tbio Non-IDG -1.72517 54.8 64
Nuclear factor of activated T-cells, cytoplasmic 2 NFATC2 Tbio Transcription Factor -2.43207 259.4 365
Fos-related antigen 1 FOSL1 Tbio Transcription Factor -2.39870 235.8 243
C-C motif chemokine 2 CCL2 Tchem Non-IDG -3.84820 7088.3 1260
Matrix Gla protein MGP Tbio Non-IDG -2.97429 878.1 151
Thrombomodulin THBD Tbio Non-IDG -3.31892 1993.7 492
Upstream stimulatory factor 2 USF2 Tbio Transcription Factor -2.58142 361.7 287
Nitric oxide synthase, endothelial NOS3 Tchem Enzyme -3.96497 9525.3 1195
Integrin beta-4 ITGB4 Tbio Non-IDG -2.26591 177.4 704