Development Level

Tbio 32 | 11,445
Tchem 7 | 1,598
Tclin 5 | 613

IMPC Phenotype

enlarged heart 3 | 210
abnormal seminal vesicle morph... 2 | 114
decreased circulating bilirubi... 2 | 19
decreased circulating serum al... 2 | 82
decreased lymphocyte cell numb... 2 | 83
decreased total body fat amoun... 2 | 207
increased bone mineral content 2 | 108
increased heart weight 2 | 62
increased neutrophil cell numb... 2 | 46
abnormal behavior 1 | 298
abnormal coat-hair pigmentatio... 1 | 64
abnormal femur morphology 1 | 14
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal skin morphology 1 | 50
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating phosphat... 1 | 27
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased vertical activity 1 | 208
dilated heart left ventricle 1 | 11
impaired glucose tolerance 1 | 75
increased blood urea nitrogen ... 1 | 48
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating phosphat... 1 | 26
increased circulating triglyce... 1 | 42
increased large unstained cell... 1 | 5
increased mean corpuscular hem... 1 | 36
increased red blood cell distr... 1 | 34
mydriasis 1 | 6
persistence of hyaloid vascula... 1 | 33
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 34 | 11,493
ovarian cancer 34 | 8,520
glioblastoma 31 | 5,792
Breast cancer 29 | 3,578
Cancer 26 | 2,499
osteosarcoma 26 | 7,950
pancreatic cancer 25 | 2,398
atypical teratoid / rhabdoid tumor 24 | 5,112
interstitial cystitis 24 | 2,312
lung cancer 24 | 4,740
malignant mesothelioma 24 | 3,232
psoriasis 24 | 6,694
ependymoma 23 | 4,679
lung adenocarcinoma 23 | 2,716
Astrocytoma, Pilocytic 22 | 3,081
adult high grade glioma 22 | 3,801
cystic fibrosis 21 | 1,696
invasive ductal carcinoma 21 | 2,951
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,955
medulloblastoma, large-cell 20 | 6,241
non-small cell lung cancer 20 | 2,890
Kidney cancer 19 | 2,613
Duchenne muscular dystrophy 16 | 601
ductal carcinoma in situ 16 | 1,745
gastric carcinoma 16 | 807
lung carcinoma 16 | 2,843
ulcerative colitis 16 | 1,819
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,291
juvenile dermatomyositis 15 | 1,187
primary pancreatic ductal adenocarcinoma 15 | 1,109
autosomal dominant Emery-Dreifuss muscular dystrophy 14 | 510
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,989
nasopharyngeal carcinoma 14 | 1,058
Kidney disease 13 | 430
diabetes mellitus 13 | 1,728
oligodendroglioma 13 | 2,850
Becker muscular dystrophy 12 | 191
adrenocortical carcinoma 12 | 1,428
breast carcinoma 12 | 1,638
colon cancer 12 | 1,478
pituitary cancer 12 | 1,972
primitive neuroectodermal tumor 12 | 3,035
tuberculosis 12 | 2,010
Liver Cirrhosis, Experimental 11 | 769
group 3 medulloblastoma 11 | 4,104
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,962
subependymal giant cell astrocytoma 11 | 2,287
urothelial carcinoma 11 | 318
Atherosclerosis 10 | 291
Autosomal recessive predisposition 10 | 1,442
acute quadriplegic myopathy 10 | 1,158
dermatomyositis 10 | 966
esophageal adenocarcinoma 10 | 737
Cerebral Hemorrhage 9 | 42
Coronary artery disease 9 | 268
Spontaneous abortion 9 | 113
active ulcerative colitis 9 | 764
interstitial lung disease 9 | 298
limb girdle muscular dystrophy 2A 9 | 213
Atopic dermatitis 8 | 952
Cerebrovascular disease 8 | 238
Hypertensive disease 8 | 292
Liver Cirrhosis 8 | 181
Nephrotic Syndrome 8 | 78
Pick disease 8 | 1,894
Schizophrenia 8 | 1,160
active Crohn's disease 8 | 922
Endometriosis 7 | 540
Epilepsy 7 | 792
Increase in blood pressure 7 | 119
Osteoporosis 7 | 363
Proteinuria 7 | 144
Seizures 7 | 596
Thrombocytopenia 7 | 197
nephrosclerosis 7 | 333
pterygium 7 | 76
Abortion, Spontaneous 6 | 109
Alport syndrome 6 | 21
Congenital deafness 6 | 185
Deafness 6 | 198
Diabetic Nephropathies 6 | 37
Diabetic Nephropathy 6 | 34
Epistaxis 6 | 43
Gastrointestinal Hemorrhage 6 | 52
Hearing Loss, Partial 6 | 185
Myopia 6 | 176
Neoplasm Metastasis 6 | 168
Prostatic Neoplasms 6 | 495
Pulmonary Fibrosis 6 | 106
group 4 medulloblastoma 6 | 1,855
hearing impairment 6 | 199
non primary Sjogren syndrome sicca 6 | 891
Heart disease 5 | 306
Hypertension 5 | 396
astrocytic glioma 5 | 2,597
astrocytoma 5 | 1,146
cutaneous lupus erythematosus 5 | 1,057
fibroadenoma 5 | 559
pediatric high grade glioma 5 | 1,064
sonic hedgehog group medulloblastoma 5 | 467

Tissue

Blood and immune system 43 | 16,909
Digestive Tract 43 | 17,369
Endocrine System 43 | 18,159
Female tissues 43 | 17,400
Liver and Pancreas 43 | 16,750
Respiratory system 43 | 16,393
Skin and soft tissues 43 | 17,230
Male tissues 42 | 17,142
Urinary Tract 42 | 16,678
Cardiovascular System 41 | 15,192
Nervous System 41 | 16,725

Target Family

Non-IDG 36 | 12,091
Kinase 4 | 634
Enzyme 2 | 4,145
Transcription Factor 2 | 1,400

PathwayCommons: pid Pathway

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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Junctional adhesion molecule A F11R Tbio Non-IDG -2.56739 380.0 394
Fibronectin FN1 Tchem Non-IDG -3.09873 1208.8 1583
Collagen alpha-1(IV) chain COL4A1 Tbio Non-IDG -2.28595 186.9 391
Fibrinogen alpha chain FGA Tbio Non-IDG -2.88066 753.1 595
Laminin subunit gamma-1 LAMC1 Tbio Non-IDG -1.79184 56.7 318
Fibrinogen gamma chain FGG Tbio Non-IDG -2.21041 158.7 384
Transforming growth factor-beta-induced protein ig-h3 TGFBI Tbio Non-IDG -2.63615 441.5 287
Tenascin TNC Tbio Non-IDG -2.34421 216.5 642
Fibrillin-1 FBN1 Tbio Non-IDG -3.08679 1236.3 325
Integrin alpha-IIb ITGA2B Tclin Non-IDG -3.52120 3309.8 1170