Development Level

Tbio 13 | 11,445
Tchem 6 | 1,598
Tclin 2 | 613

Collection

Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

increased total body fat amoun... 2 | 134
abnormal bone mineralization 1 | 38
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal startle reflex 1 | 15
decreased body length 1 | 101
decreased body weight 1 | 161
decreased circulating glucose ... 1 | 126
decreased circulating glycerol... 1 | 16
decreased lean body mass 1 | 135
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
hydrometra 1 | 53
increased bone mineral density 1 | 72
increased circulating insulin ... 1 | 3
increased startle reflex 1 | 112
mammalian phenotype 1 | 17
preweaning lethality, complete... 1 | 979
small superior vagus ganglion 1 | 74

Disease

Carcinoma 17 | 11,493
ovarian cancer 15 | 8,520
lung cancer 11 | 4,740
medulloblastoma, large-cell 11 | 6,241
osteosarcoma 11 | 7,950
Cancer 10 | 2,499
adult high grade glioma 8 | 3,801
atypical teratoid / rhabdoid tumor 8 | 5,112
glioblastoma 8 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
psoriasis 8 | 6,694
Breast cancer 7 | 3,578
group 3 medulloblastoma 7 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
diabetes mellitus 6 | 1,728
ependymoma 6 | 4,679
lung adenocarcinoma 6 | 2,716
non-small cell lung cancer 6 | 2,890
primitive neuroectodermal tumor 6 | 3,035
Kidney cancer 5 | 2,613
Schizophrenia 5 | 1,160
adrenocortical carcinoma 5 | 1,428
astrocytic glioma 5 | 2,597
oligodendroglioma 5 | 2,850
Alzheimer's disease 4 | 658
Astrocytoma, Pilocytic 4 | 3,081
Intellectual disability 4 | 1,016
Liver cancer 4 | 604
Osteoporosis 4 | 363
Prostatic Neoplasms 4 | 495
breast carcinoma 4 | 1,638
malignant mesothelioma 4 | 3,232
tuberculosis 4 | 2,010
ulcerative colitis 4 | 1,819
Carcinoma, Hepatocellular 3 | 228
Dull intelligence 3 | 645
Endometrial cancer 3 | 311
Familial adenomatous polyposis 3 | 32
Hypertension 3 | 396
Hypertensive disease 3 | 292
Increased hepatocellular carcinoma risk 3 | 27
Increased incidence of hepatocellular carcinoma 3 | 27
Liver carcinoma 3 | 240
Low intelligence 3 | 645
Malabsorption 3 | 82
Melanoma 3 | 711
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Micronodular cirrhosis 3 | 12
Osteoarthritis 3 | 184
Parkinson's disease 3 | 392
Pick disease 3 | 1,894
Poor school performance 3 | 645
Somatic mutation 3 | 61
Stomach Neoplasms 3 | 300
Subacute progressive viral hepatitis 3 | 9
Vascular disease 3 | 319
astrocytoma 3 | 1,146
colon cancer 3 | 1,478
ductal carcinoma in situ 3 | 1,745
esophageal adenocarcinoma 3 | 737
fibroadenoma 3 | 559
group 4 medulloblastoma 3 | 1,855
hepatocellular carcinoma 3 | 547
interstitial cystitis 3 | 2,312
invasive ductal carcinoma 3 | 2,951
lung carcinoma 3 | 2,843
medulloblastoma 3 | 720
pancreatic cancer 3 | 2,398
spina bifida 3 | 1,074
subependymal giant cell astrocytoma 3 | 2,287
Abnormality of retinal pigmentation 2 | 111
Adenoma 2 | 167
Amyotrophic lateral sclerosis 2 | 451
Bipolar disorder in remission 2 | 19
Colonic Neoplasms 2 | 142
Colorectal Neoplasms 2 | 243
Eye disease 2 | 62
Fever 2 | 138
Heart disease 2 | 306
Highly variable severity 2 | 157
Kidney disease 2 | 430
Large intestine cancer 2 | 126
Liver neoplasms 2 | 130
Long philtrum 2 | 137
Lung Neoplasms 2 | 232
Lung disease 2 | 142
Major Depressive Disorder 2 | 301
Mammary Neoplasms 2 | 425
Neoplasm Metastasis 2 | 168
Neurodevelopmental Disorders 2 | 70
Retinal pigment epithelial abnormality 2 | 111
Skin cancer 2 | 469
Toxic encephalopathy 2 | 141
Variable expressivity 2 | 157
X-linked cerebral adrenoleukodystrophy 2 | 116
acute quadriplegic myopathy 2 | 1,158
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
posterior fossa group A ependymoma 2 | 468

Tissue

Digestive Tract 20 | 17,369
Female tissues 20 | 17,400
Male tissues 20 | 17,142
Respiratory system 20 | 16,393
Skin and soft tissues 20 | 17,230
Blood and immune system 19 | 16,909
Cardiovascular System 19 | 15,192
Endocrine System 19 | 18,159
Liver and Pancreas 19 | 16,750
Nervous System 19 | 16,725
Urinary Tract 19 | 16,678

Target Family

Non-IDG 13 | 12,091
Kinase 6 | 634
Enzyme 1 | 4,145
GPCR 1 | 408

PathwayCommons: pid Pathway

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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ran-binding protein 3 RANBP3 Tbio Non-IDG -1.41852 21.4 158
Phosphatidylinositol 4-phosphate 5-kinase type-1 beta PIP5K1B Tbio Kinase -1.07498 11.3 96
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform PPP2R5A Tchem Enzyme -0.54568 3.09 202
Adenomatous polyposis coli protein APC Tbio Non-IDG -1.90646 66.5 508
Frizzled-5 FZD5 Tbio GPCR -1.54924 30.5 307
Casein kinase I isoform gamma-1 CSNK1G1 Tchem Kinase -0.52091 3.22 224
Cullin-3 CUL3 Tbio Non-IDG -3.26322 1670.8 307
Phosphatidylinositol 4-kinase type 2-alpha PI4K2A Tbio Kinase -2.88003 745.1 146
Glycogen synthase kinase-3 alpha GSK3A Tclin Kinase -1.82880 53.1 840
Glycogen synthase kinase-3 beta GSK3B Tclin Kinase -3.00390 610.8 955