Development Level

Tbio 37 | 11,445
Tchem 18 | 1,598
Tclin 11 | 613

IMPC Phenotype

preweaning lethality, complete... 3 | 979
preweaning lethality, incomple... 3 | 499
abnormal seminal vesicle morph... 2 | 114
enlarged heart 2 | 210
increased neutrophil cell numb... 2 | 46
abnormal behavioral response t... 1 | 66
abnormal femur morphology 1 | 14
abnormal heart morphology 1 | 162
decreased blood urea nitrogen ... 1 | 51
decreased circulating LDL chol... 1 | 38
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased lymphocyte cell numb... 1 | 83
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
dilated heart left ventricle 1 | 11
embryonic lethality prior to t... 1 | 278
hemorrhage 1 | 23
hydrometra 1 | 53
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased heart left ventricle... 1 | 4
increased heart weight 1 | 62
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased monocyte cell number 1 | 63
prenatal lethality prior to he... 1 | 87
small superior vagus ganglion 1 | 74

Disease

Cancer 49 | 2,499
osteosarcoma 44 | 7,950
Carcinoma 41 | 11,493
ovarian cancer 40 | 8,520
psoriasis 33 | 6,694
lung cancer 31 | 4,740
medulloblastoma, large-cell 29 | 6,241
Breast cancer 23 | 3,578
glioblastoma 23 | 5,792
atypical teratoid / rhabdoid tumor 21 | 5,112
Asthma 20 | 385
invasive ductal carcinoma 19 | 2,951
Kidney cancer 17 | 2,613
Rheumatoid arthritis 17 | 1,191
interstitial cystitis 17 | 2,312
pancreatic cancer 17 | 2,398
group 3 medulloblastoma 16 | 4,104
lung carcinoma 16 | 2,843
malignant mesothelioma 16 | 3,232
Schizophrenia 15 | 1,160
subependymal giant cell astrocytoma 15 | 2,287
adult high grade glioma 14 | 3,801
diabetes mellitus 14 | 1,728
ependymoma 13 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
lung adenocarcinoma 13 | 2,716
non-small cell lung cancer 13 | 2,890
tuberculosis 13 | 2,010
Atopic dermatitis 12 | 952
ductal carcinoma in situ 12 | 1,745
juvenile dermatomyositis 12 | 1,187
primitive neuroectodermal tumor 12 | 3,035
Obesity 11 | 678
breast carcinoma 11 | 1,638
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
pituitary cancer 11 | 1,972
ulcerative colitis 11 | 1,819
Allergic hypersensitivity disease 10 | 126
Anemia 10 | 365
Inflammatory bowel disease 10 | 151
Vascular disease 10 | 319
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
Allergic rhinitis 9 | 94
Arthritis 9 | 290
Astrocytoma, Pilocytic 9 | 3,081
Hypereosinophilic syndrome 9 | 71
Hyperglycemia 9 | 137
Liver Cirrhosis, Experimental 9 | 769
Multiple Sclerosis 9 | 540
active Crohn's disease 9 | 922
active ulcerative colitis 9 | 764
gastric carcinoma 9 | 807
oligodendroglioma 9 | 2,850
periodontitis 9 | 293
primary Sjogren syndrome 9 | 735
primary pancreatic ductal adenocarcinoma 9 | 1,109
Autosomal recessive predisposition 8 | 1,442
colon cancer 8 | 1,478
cutaneous lupus erythematosus 8 | 1,057
group 4 medulloblastoma 8 | 1,855
interstitial lung disease 8 | 298
mucosa-associated lymphoid tissue lymphoma 8 | 484
Alzheimer's disease 7 | 658
Carcinoma, Hepatocellular 7 | 228
Fever 7 | 138
Hypersensitivity reaction type II disease 7 | 253
Hypertension 7 | 396
Kidney disease 7 | 430
Liver carcinoma 7 | 240
Lung Neoplasms 7 | 232
Pick disease 7 | 1,894
Pneumonia 7 | 174
Pulmonary Fibrosis 7 | 106
Thrombocytopenia 7 | 197
adrenocortical carcinoma 7 | 1,428
astrocytoma 7 | 1,146
nasopharyngeal carcinoma 7 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
Autistic Disorder 6 | 364
Common cold 6 | 67
Dermatitis 6 | 157
Dermatitis, Atopic 6 | 37
Diarrhea 6 | 253
Duchenne muscular dystrophy 6 | 601
Hepatitis C 6 | 94
Hypertensive disease 6 | 292
Immune system cancer 6 | 140
Lung disease 6 | 142
Lymphoid leukemia 6 | 160
Multiple myeloma 6 | 1,332
Myocardial Ischemia 6 | 169
Prostatic Neoplasms 6 | 495
Severe combined immunodeficiency 6 | 51
Splenomegaly 6 | 190
astrocytic glioma 6 | 2,597
esophageal adenocarcinoma 6 | 737
pediatric high grade glioma 6 | 1,064
urothelial carcinoma 6 | 318
Mastocytosis 5 | 27
pancreatic carcinoma 5 | 562

Tissue

Digestive Tract 62 | 17,369
Endocrine System 62 | 18,159
Respiratory system 62 | 16,393
Blood and immune system 61 | 16,909
Female tissues 61 | 17,400
Liver and Pancreas 61 | 16,750
Skin and soft tissues 61 | 17,230
Urinary Tract 61 | 16,678
Male tissues 60 | 17,142
Cardiovascular System 59 | 15,192
Nervous System 58 | 16,725

Target Family

Non-IDG 34 | 12,091
Transcription Factor 14 | 1,400
Kinase 10 | 634
Enzyme 7 | 4,145
GPCR 1 | 408

PathwayCommons: pid Pathway

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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transcription factor PU.1 SPI1 Tbio Transcription Factor -3.05079 1139.0 397
CCAAT/enhancer-binding protein beta CEBPB Tbio Transcription Factor -2.96589 857.9 436
CD40 ligand CD40LG Tbio Non-IDG -4.58203 37578.3 1461
Immunoglobulin heavy constant gamma 1 IGHG1 Tbio Non-IDG 0.00000 0
Immunoglobulin heavy constant epsilon IGHE Tclin Non-IDG 0.00000 0
Immunoglobulin heavy constant gamma 3 IGHG3 Tbio Non-IDG 0.00000 0
Suppressor of cytokine signaling 5 SOCS5 Tbio Non-IDG -2.04740 106.6 135
Eotaxin CCL11 Tbio Non-IDG -2.99518 992.7 285
Poly [ADP-ribose] polymerase 14 PARP14 Tbio Enzyme -1.51062 31.2 35
Transcription factor IIIA GTF3A Tbio Transcription Factor -2.35179 204.7 171