Development Level

Tbio 36 | 11,445
Tchem 2 | 1,598
Tclin 1 | 613

IMPC Phenotype

abnormal behavior 2 | 298
hyperactivity 2 | 148
hypoactivity 2 | 132
increased mean corpuscular hem... 2 | 96
preweaning lethality, incomple... 2 | 499
abnormal coping response 1 | 1
abnormal digestive system phys... 1 | 1
abnormal hair growth 1 | 10
decreased body weight 1 | 161
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased fasted circulating g... 1 | 65
decreased heart left ventricle... 1 | 28
decreased mean corpuscular hem... 1 | 31
decreased total body fat amoun... 1 | 207
enlarged lymph nodes 1 | 37
impaired righting response 1 | 26
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating sodium l... 1 | 71
increased grip strength 1 | 41
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased vertical activity 1 | 24
preweaning lethality, complete... 1 | 979
short tibia 1 | 97
thin ventricular wall 1 | 24

Disease

Carcinoma 33 | 11,493
ovarian cancer 26 | 8,520
glioblastoma 23 | 5,792
medulloblastoma, large-cell 23 | 6,241
osteosarcoma 23 | 7,950
atypical teratoid / rhabdoid tumor 21 | 5,112
Kidney cancer 20 | 2,613
group 3 medulloblastoma 18 | 4,104
Astrocytoma, Pilocytic 17 | 3,081
adult high grade glioma 17 | 3,801
ependymoma 17 | 4,679
oligodendroglioma 16 | 2,850
primitive neuroectodermal tumor 16 | 3,035
astrocytic glioma 14 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
lung cancer 13 | 4,740
Breast cancer 12 | 3,578
psoriasis 12 | 6,694
subependymal giant cell astrocytoma 12 | 2,287
Cancer 11 | 2,499
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
invasive ductal carcinoma 11 | 2,951
non-small cell lung cancer 11 | 2,890
group 4 medulloblastoma 10 | 1,855
interstitial cystitis 10 | 2,312
pituitary cancer 10 | 1,972
Pick disease 9 | 1,894
malignant mesothelioma 9 | 3,232
pancreatic cancer 9 | 2,398
ulcerative colitis 8 | 1,819
Intellectual disability 7 | 1,016
Melanoma 7 | 711
ductal carcinoma in situ 7 | 1,745
lung carcinoma 7 | 2,843
spina bifida 7 | 1,074
Liver cancer 6 | 604
Skin cancer 6 | 469
lung adenocarcinoma 6 | 2,716
pediatric high grade glioma 6 | 1,064
primary Sjogren syndrome 6 | 735
Endometrial cancer 5 | 311
aldosterone-producing adenoma 5 | 665
breast carcinoma 5 | 1,638
cystic fibrosis 5 | 1,696
tuberculosis 5 | 2,010
Waldenstrons macroglobulinemia 4 | 765
colon cancer 4 | 1,478
primary pancreatic ductal adenocarcinoma 4 | 1,109
Autosomal recessive predisposition 3 | 1,442
Cardiovascular system disease 3 | 246
Chronic Lymphocytic Leukemia 3 | 262
Dull intelligence 3 | 645
Liver Cirrhosis, Experimental 3 | 769
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Polycystic ovary syndrome 3 | 360
Poor school performance 3 | 645
Prostatic Neoplasms 3 | 495
Schizophrenia 3 | 1,160
acute quadriplegic myopathy 3 | 1,158
adrenocortical carcinoma 3 | 1,428
cutaneous lupus erythematosus 3 | 1,057
cystic fibrosis and chronic rhinosinusitis 3 | 214
dermatomyositis 3 | 966
diabetes mellitus 3 | 1,728
esophageal adenocarcinoma 3 | 737
juvenile dermatomyositis 3 | 1,187
medulloblastoma 3 | 720
tuberculosis and treatment for 6 months 3 | 409
Adenocarcinoma of lung 2 | 142
Amyotrophic lateral sclerosis 2 | 451
Bipolar Disorder 2 | 666
Down syndrome 2 | 499
Enophthalmos 2 | 75
Heart conduction disease 2 | 83
Hypertension 2 | 396
Liver neoplasms 2 | 130
Major Depressive Disorder 2 | 301
Multiple myeloma 2 | 1,332
Neoplasm Metastasis 2 | 168
Orofacial cleft 2 | 54
Prenatal onset 2 | 139
Sensorineural Hearing Loss (disorder) 2 | 284
Short stature 2 | 531
Strabismus 2 | 270
Substance-Related Disorders 2 | 115
Unipolar Depression 2 | 250
Vascular disease 2 | 319
acute lymphocytic leukemia 2 | 33
acute myeloid leukemia 2 | 783
astrocytoma 2 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
gastric carcinoma 2 | 807
hepatocellular carcinoma 2 | 547
nasopharyngeal carcinoma 2 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
periodontitis 2 | 293
progressive supranuclear palsy 2 | 676

Tissue

Blood and immune system 39 | 16,909
Cardiovascular System 39 | 15,192
Digestive Tract 39 | 17,369
Endocrine System 39 | 18,159
Female tissues 39 | 17,400
Liver and Pancreas 39 | 16,750
Male tissues 39 | 17,142
Nervous System 39 | 16,725
Respiratory system 39 | 16,393
Skin and soft tissues 39 | 17,230
Urinary Tract 39 | 16,678

Target Family

Non-IDG 29 | 12,091
Enzyme 8 | 4,145
Kinase 2 | 634

PathwayCommons: pid Pathway

http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 137 | 137
http://pathwaycommons.org/pc2/... 125 | 125
http://pathwaycommons.org/pc2/... 102 | 102
http://pathwaycommons.org/pc2/... 87 | 87
http://pathwaycommons.org/pc2/... 87 | 87
http://pathwaycommons.org/pc2/... 85 | 85
http://pathwaycommons.org/pc2/... 82 | 82
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 77 | 77
http://pathwaycommons.org/pc2/... 74 | 74
http://pathwaycommons.org/pc2/... 74 | 74
http://pathwaycommons.org/pc2/... 71 | 71
http://pathwaycommons.org/pc2/... 71 | 71
http://pathwaycommons.org/pc2/... 70 | 70
http://pathwaycommons.org/pc2/... 70 | 70
http://pathwaycommons.org/pc2/... 69 | 69
http://pathwaycommons.org/pc2/... 67 | 67
http://pathwaycommons.org/pc2/... 67 | 67
http://pathwaycommons.org/pc2/... 67 | 67
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 65 | 65
http://pathwaycommons.org/pc2/... 65 | 65
http://pathwaycommons.org/pc2/... 65 | 65
http://pathwaycommons.org/pc2/... 64 | 64
http://pathwaycommons.org/pc2/... 64 | 64
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 62 | 62
http://pathwaycommons.org/pc2/... 61 | 61
http://pathwaycommons.org/pc2/... 60 | 60
http://pathwaycommons.org/pc2/... 59 | 59
http://pathwaycommons.org/pc2/... 59 | 59
http://pathwaycommons.org/pc2/... 58 | 58
http://pathwaycommons.org/pc2/... 57 | 57
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 55 | 55
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 53 | 53
http://pathwaycommons.org/pc2/... 53 | 53
http://pathwaycommons.org/pc2/... 53 | 53
http://pathwaycommons.org/pc2/... 51 | 51
http://pathwaycommons.org/pc2/... 50 | 50
http://pathwaycommons.org/pc2/... 50 | 50
http://pathwaycommons.org/pc2/... 50 | 50
http://pathwaycommons.org/pc2/... 49 | 49
http://pathwaycommons.org/pc2/... 49 | 49
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 45 | 45
http://pathwaycommons.org/pc2/... 45 | 45
http://pathwaycommons.org/pc2/... 44 | 44
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 41 | 41
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 36 | 36

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Rho GTPase-activating protein 9 ARHGAP9 Tbio Enzyme -1.74771 54.3 35
T-lymphoma invasion and metastasis-inducing protein 2 TIAM2 Tbio Non-IDG -1.27322 19.7 151
Beta-chimaerin CHN2 Tbio Non-IDG -1.78873 58.0 149
Rho GDP-dissociation inhibitor 1 ARHGDIA Tchem Non-IDG -2.56885 370.1 382
Rho guanine nucleotide exchange factor 25 ARHGEF25 Tbio Non-IDG -1.43926 31.5 50
Abl interactor 1 ABI1 Tbio Non-IDG -1.99953 104.1 264
Breakpoint cluster region protein BCR Tclin Non-IDG -2.99605 934.2 437
Active breakpoint cluster region-related protein ABR Tbio Non-IDG -2.33418 216.1 37
Ras-specific guanine nucleotide-releasing factor 2 RASGRF2 Tbio Non-IDG -1.31521 23.7 21
Dedicator of cytokinesis protein 6 DOCK6 Tbio Non-IDG -1.78091 57.0 16