Development Level

Tchem 14 | 1,598
Tbio 7 | 11,445
Tclin 5 | 613

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal bone structure 1 | 187
abnormal eye morphology 1 | 68
abnormal heart morphology 1 | 162
abnormal skin morphology 1 | 50
abnormal snout morphology 1 | 23
anophthalmia 1 | 33
decreased fasted circulating g... 1 | 65
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
increased grip strength 1 | 41
increased heart left ventricle... 1 | 4
male infertility 1 | 123
preweaning lethality, incomple... 1 | 499

Disease

Cancer 22 | 2,499
ovarian cancer 19 | 8,520
Carcinoma 18 | 11,493
glioblastoma 17 | 5,792
osteosarcoma 15 | 7,950
psoriasis 14 | 6,694
lung cancer 13 | 4,740
medulloblastoma, large-cell 13 | 6,241
Breast cancer 12 | 3,578
atypical teratoid / rhabdoid tumor 12 | 5,112
lung adenocarcinoma 11 | 2,716
adult high grade glioma 10 | 3,801
diabetes mellitus 10 | 1,728
invasive ductal carcinoma 10 | 2,951
primitive neuroectodermal tumor 10 | 3,035
Breast Neoplasms 9 | 445
Mammary Neoplasms 9 | 425
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
Kidney cancer 8 | 2,613
Prostatic Neoplasms 8 | 495
ependymoma 8 | 4,679
Carcinoma, Squamous Cell 7 | 110
Heart disease 7 | 306
Neoplasm Metastasis 7 | 168
Pick disease 7 | 1,894
Schizophrenia 7 | 1,160
Squamous cell carcinoma 7 | 129
Stomach Neoplasms 7 | 300
group 3 medulloblastoma 7 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
pancreatic cancer 7 | 2,398
tuberculosis 7 | 2,010
Arthritis 6 | 290
Bipolar Disorder 6 | 666
Cardiomegaly 6 | 116
Depressive disorder 6 | 409
Diabetic retinopathy 6 | 56
Hyperglycemia 6 | 137
Hypertension 6 | 396
astrocytic glioma 6 | 2,597
breast carcinoma 6 | 1,638
cystic fibrosis 6 | 1,696
group 4 medulloblastoma 6 | 1,855
juvenile dermatomyositis 6 | 1,187
oligodendroglioma 6 | 2,850
ulcerative colitis 6 | 1,819
Alzheimer's disease 5 | 658
Astrocytoma, Pilocytic 5 | 3,081
Glaucoma 5 | 239
Hypertensive disease 5 | 292
Kidney disease 5 | 430
Lung disease 5 | 142
Lymphedema 5 | 42
Mental Depression 5 | 333
Myopia 5 | 176
Ovarian Neoplasms 5 | 102
Proteinuria 5 | 144
Vascular disease 5 | 319
astrocytoma 5 | 1,146
dermatomyositis 5 | 966
ductal carcinoma in situ 5 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
lung carcinoma 5 | 2,843
non-small cell lung cancer 5 | 2,890
Atherosclerosis 4 | 291
Brain Ischemia 4 | 110
Cataract 4 | 297
Cognitive delay 4 | 608
Down syndrome 4 | 499
Downward slant of palpebral fissure 4 | 158
Dull intelligence 4 | 645
Endometrial cancer 4 | 311
Fetal Growth Retardation 4 | 189
Global developmental delay 4 | 608
Heart failure 4 | 162
Hemangioma 4 | 69
Hypoplastic mandible condyle 4 | 275
Intellectual disability 4 | 1,016
Liver Cirrhosis, Experimental 4 | 769
Low intelligence 4 | 645
Lung Neoplasms 4 | 232
Major Depressive Disorder 4 | 301
Mandibular hypoplasia 4 | 275
Mental Retardation 4 | 645
Mental and motor retardation 4 | 608
Mental deficiency 4 | 645
Micrognathism 4 | 275
Mood Disorders 4 | 184
Multiple myeloma 4 | 1,332
Obesity 4 | 678
Orbital separation excessive 4 | 244
Pectus excavatum 4 | 100
Poor school performance 4 | 645
Rheumatoid arthritis 4 | 1,191
Short stature 4 | 531
Somatic mutation 4 | 61
interstitial cystitis 4 | 2,312
nasopharyngeal carcinoma 4 | 1,058
pancreatic carcinoma 4 | 562
primary pancreatic ductal adenocarcinoma 4 | 1,109

Tissue

Blood and immune system 26 | 16,909
Cardiovascular System 26 | 15,192
Digestive Tract 26 | 17,369
Endocrine System 26 | 18,159
Female tissues 26 | 17,400
Liver and Pancreas 26 | 16,750
Male tissues 26 | 17,142
Nervous System 26 | 16,725
Respiratory system 26 | 16,393
Skin and soft tissues 26 | 17,230
Urinary Tract 26 | 16,678

Target Family

Kinase 10 | 634
Non-IDG 10 | 12,091
Enzyme 5 | 4,145
Transcription Factor 1 | 1,400

PathwayCommons: pid Pathway

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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
CD2-associated protein CD2AP Tbio Non-IDG -3.44533 2735.9 82
Protein kinase C beta type PRKCB Tchem Kinase -2.00437 93.5 598
Vascular endothelial growth factor receptor 1 FLT1 Tclin Kinase -3.38913 2189.4 953
SHC-transforming protein 2 SHC2 Tbio Non-IDG -2.47843 293.4 113
Placenta growth factor PGF Tclin Non-IDG -3.52194 3429.0 630
Nitric oxide synthase, endothelial NOS3 Tchem Enzyme -3.96497 9525.3 1195
Mitogen-activated protein kinase 1 MAPK1 Tchem Kinase -3.18822 1239.4 1248
cAMP-dependent protein kinase catalytic subunit alpha PRKACA Tchem Kinase -1.09531 11.7 331
Mitogen-activated protein kinase 3 MAPK3 Tchem Kinase -3.66226 3484.0 1440
3-phosphoinositide-dependent protein kinase 1 PDPK1 Tchem Kinase -2.12025 204.9 608