Development Level

Tchem 25 | 1,598
Tbio 19 | 11,445
Tclin 9 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 6 | 979
embryonic lethality prior to t... 5 | 278
preweaning lethality, incomple... 5 | 499
abnormal behavior 3 | 298
abnormal embryo size 3 | 220
decreased eosinophil cell numb... 2 | 24
decreased neutrophil cell numb... 2 | 42
decreased vertical activity 2 | 208
embryonic growth retardation 2 | 106
embryonic lethality prior to o... 2 | 239
increased circulating HDL chol... 2 | 80
increased circulating choleste... 2 | 66
increased grip strength 2 | 41
male infertility 2 | 123
abnormal bone mineralization 1 | 38
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal femur morphology 1 | 14
abnormal forebrain development 1 | 20
abnormal heart left ventricle ... 1 | 16
abnormal hindbrain development 1 | 16
abnormal lens morphology 1 | 81
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal ovary morphology 1 | 7
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal snout morphology 1 | 23
absent epididymis 1 | 3
absent seminal vesicle 1 | 4
absent vibrissae 1 | 12
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased body length 1 | 101
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased exploration in new e... 1 | 11
decreased fasted circulating g... 1 | 65
decreased large unstained cell... 1 | 11
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased monocyte cell number 1 | 8
decreased total body fat amoun... 1 | 207
female infertility 1 | 60
hemorrhage 1 | 23
hyperactivity 1 | 148
increased body temperature 1 | 9
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased caudal vertebrae num... 1 | 7
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased mean platelet volume 1 | 45
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
short tibia 1 | 97
small uterus 1 | 3
tremors 1 | 39

Disease

Carcinoma 46 | 11,493
osteosarcoma 41 | 7,950
ovarian cancer 36 | 8,520
Cancer 35 | 2,499
psoriasis 32 | 6,694
lung cancer 25 | 4,740
glioblastoma 24 | 5,792
medulloblastoma, large-cell 24 | 6,241
Breast cancer 22 | 3,578
atypical teratoid / rhabdoid tumor 20 | 5,112
group 3 medulloblastoma 16 | 4,104
diabetes mellitus 15 | 1,728
Prostatic Neoplasms 14 | 495
Breast Neoplasms 12 | 445
Kidney cancer 12 | 2,613
Mammary Neoplasms 12 | 425
Rheumatoid arthritis 12 | 1,191
Schizophrenia 12 | 1,160
adult high grade glioma 12 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
invasive ductal carcinoma 12 | 2,951
malignant mesothelioma 12 | 3,232
primitive neuroectodermal tumor 12 | 3,035
subependymal giant cell astrocytoma 12 | 2,287
astrocytoma 11 | 1,146
group 4 medulloblastoma 11 | 1,855
lung adenocarcinoma 11 | 2,716
tuberculosis 11 | 2,010
Multiple myeloma 10 | 1,332
ependymoma 10 | 4,679
oligodendroglioma 10 | 2,850
Vascular disease 9 | 319
colon cancer 9 | 1,478
lung carcinoma 9 | 2,843
Astrocytoma, Pilocytic 8 | 3,081
Cryptorchidism 8 | 296
Endometriosis 8 | 540
Obesity 8 | 678
breast carcinoma 8 | 1,638
interstitial cystitis 8 | 2,312
pituitary cancer 8 | 1,972
Bipolar Disorder 7 | 666
Mood Disorders 7 | 184
Waldenstrons macroglobulinemia 7 | 765
acute myeloid leukemia 7 | 783
acute quadriplegic myopathy 7 | 1,158
astrocytic glioma 7 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
non-small cell lung cancer 7 | 2,890
pancreatic cancer 7 | 2,398
spina bifida 7 | 1,074
Alzheimer's disease 6 | 658
Hypertension 6 | 396
Kidney disease 6 | 430
Lung Neoplasms 6 | 232
Parkinson's disease 6 | 392
Penile hypospadias 6 | 106
Primary cutaneous T-cell lymphoma 6 | 29
Prostate cancer 6 | 175
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
ulcerative colitis 6 | 1,819
Arthritis 5 | 290
Asthma 5 | 385
Carcinoma, Squamous Cell 5 | 110
Epilepsy 5 | 792
Failure to gain weight 5 | 365
Heart disease 5 | 306
Hyperglycemia 5 | 137
Intellectual disability 5 | 1,016
Osteoporosis 5 | 363
Pediatric failure to thrive 5 | 365
Seizures 5 | 596
Short stature 5 | 531
Squamous cell carcinoma 5 | 129
Stomach Neoplasms 5 | 300
dermatomyositis 5 | 966
ductal carcinoma in situ 5 | 1,745
pediatric high grade glioma 5 | 1,064
Acquired scoliosis 4 | 281
Adenoid Cystic Carcinoma 4 | 99
Broad flat nasal bridge 4 | 236
Carcinoma, Adenoid Cystic 4 | 99
Carcinoma, Hepatocellular 4 | 228
Colonic Neoplasms 4 | 142
Crohn's disease 4 | 321
Curvature of spine 4 | 282
Depressive disorder 4 | 409
Immune system cancer 4 | 140
Liver carcinoma 4 | 240
Major Depressive Disorder 4 | 301
Male infertility 4 | 206
Mental Depression 4 | 333
Nasal bridge wide 4 | 236
Pick disease 4 | 1,894
Strabismus 4 | 270
aldosterone-producing adenoma 4 | 665
fibroadenoma 4 | 559
juvenile dermatomyositis 4 | 1,187
pancreatic carcinoma 4 | 562

Tissue

Digestive Tract 54 | 17,369
Endocrine System 54 | 18,159
Male tissues 54 | 17,142
Nervous System 54 | 16,725
Skin and soft tissues 54 | 17,230
Blood and immune system 53 | 16,909
Female tissues 53 | 17,400
Liver and Pancreas 53 | 16,750
Respiratory system 52 | 16,393
Urinary Tract 52 | 16,678
Cardiovascular System 49 | 15,192

Target Family

Epigenetic 12 | 242
Transcription Factor 12 | 1,400
Nuclear Receptor 8 | 48
Kinase 7 | 634
Non-IDG 7 | 12,091
Enzyme 6 | 4,145
TF/Epigenetic 2 | 38

PathwayCommons: pid Pathway

http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 137 | 137
http://pathwaycommons.org/pc2/... 125 | 125
http://pathwaycommons.org/pc2/... 102 | 102
http://pathwaycommons.org/pc2/... 87 | 87
http://pathwaycommons.org/pc2/... 87 | 87
http://pathwaycommons.org/pc2/... 85 | 85
http://pathwaycommons.org/pc2/... 82 | 82
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 80 | 80
http://pathwaycommons.org/pc2/... 77 | 77
http://pathwaycommons.org/pc2/... 74 | 74
http://pathwaycommons.org/pc2/... 74 | 74
http://pathwaycommons.org/pc2/... 71 | 71
http://pathwaycommons.org/pc2/... 71 | 71
http://pathwaycommons.org/pc2/... 70 | 70
http://pathwaycommons.org/pc2/... 70 | 70
http://pathwaycommons.org/pc2/... 69 | 69
http://pathwaycommons.org/pc2/... 67 | 67
http://pathwaycommons.org/pc2/... 67 | 67
http://pathwaycommons.org/pc2/... 67 | 67
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 66 | 66
http://pathwaycommons.org/pc2/... 65 | 65
http://pathwaycommons.org/pc2/... 65 | 65
http://pathwaycommons.org/pc2/... 65 | 65
http://pathwaycommons.org/pc2/... 64 | 64
http://pathwaycommons.org/pc2/... 64 | 64
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 62 | 62
http://pathwaycommons.org/pc2/... 61 | 61
http://pathwaycommons.org/pc2/... 60 | 60
http://pathwaycommons.org/pc2/... 59 | 59
http://pathwaycommons.org/pc2/... 59 | 59
http://pathwaycommons.org/pc2/... 58 | 58
http://pathwaycommons.org/pc2/... 57 | 57
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 55 | 55
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 54 | 54
http://pathwaycommons.org/pc2/... 53 | 53
http://pathwaycommons.org/pc2/... 53 | 53
http://pathwaycommons.org/pc2/... 53 | 53
http://pathwaycommons.org/pc2/... 51 | 51
http://pathwaycommons.org/pc2/... 50 | 50
http://pathwaycommons.org/pc2/... 50 | 50
http://pathwaycommons.org/pc2/... 50 | 50
http://pathwaycommons.org/pc2/... 49 | 49
http://pathwaycommons.org/pc2/... 49 | 49
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 46 | 46
http://pathwaycommons.org/pc2/... 45 | 45
http://pathwaycommons.org/pc2/... 45 | 45
http://pathwaycommons.org/pc2/... 44 | 44
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 41 | 41
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 36 | 36

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histone-arginine methyltransferase CARM1 CARM1 Tchem Epigenetic -2.04034 130.8 476
Nuclear receptor subfamily 2 group C member 1 NR2C1 Tbio Nuclear Receptor -1.39182 24.4 294
Forkhead box protein O1 FOXO1 Tbio Transcription Factor -3.05358 1143.3 1478
Retinoic acid receptor RXR-beta RXRB Tclin Nuclear Receptor -1.72557 49.3 274
Amyloid protein-binding protein 2 APPBP2 Tbio Non-IDG -0.46087 2.34 247
Zinc finger MIZ domain-containing protein 2 ZMIZ2 Tdark Transcription Factor -0.58991 4.21 86
Transmembrane protease serine 2 TMPRSS2 Tchem Enzyme -2.66686 438.2 221
Dual specificity mitogen-activated protein kinase kinase 4 MAP2K4 Tchem Kinase -2.43646 236.7 998
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A PDE9A Tchem Enzyme -1.92564 78.9 151
Transcription intermediary factor 1-alpha TRIM24 Tchem Epigenetic -2.15509 143.0 372