Development Level

Tbio 15 | 10,625
Tchem 9 | 1,890

IMPC Term

decreased KLRG1+ CD8 alpha bet... 1 | 8
decreased mean corpuscular vol... 1 | 50
increased NK cell number 1 | 19
increased body weight 1 | 42

Disease

ovarian cancer 16 | 8,484
Cancer 15 | 2,346
tuberculosis 13 | 1,557
glioblastoma 12 | 5,572
lung carcinoma 12 | 2,844
psoriasis 12 | 6,685
lung cancer 11 | 4,466
diabetes mellitus 10 | 1,663
medulloblastoma, large-cell 10 | 6,234
cutaneous lupus erythematosus 9 | 1,056
osteosarcoma 9 | 7,933
pilocytic astrocytoma 9 | 3,086
Arthritis 8 | 248
Breast cancer 8 | 3,094
interstitial cystitis 8 | 2,299
malignant mesothelioma 8 | 3,162
ulcerative colitis 8 | 2,087
Asthma 7 | 349
Rheumatoid Arthritis 7 | 1,160
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,289
Atherosclerosis 6 | 275
IGA Glomerulonephritis 6 | 454
gastric carcinoma 6 | 832
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,956
invasive ductal carcinoma 6 | 2,950
lung adenocarcinoma 6 | 2,713
pediatric high grade glioma 6 | 2,712
Hypersensitivity reaction type II disease 5 | 235
Lung disease 5 | 132
acute quadriplegic myopathy 5 | 1,157
breast carcinoma 5 | 1,614
cystic fibrosis 5 | 1,665
dermatomyositis 5 | 933
ependymoma 5 | 2,514
esophageal adenocarcinoma 5 | 737
group 4 medulloblastoma 5 | 1,875
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,988
juvenile dermatomyositis 5 | 1,189
mucosa-associated lymphoid tissue lymphoma 5 | 480
pancreatic cancer 5 | 2,300
periodontitis 5 | 269
subependymal giant cell astrocytoma 5 | 2,287
Duchenne muscular dystrophy 4 | 602
Inflammation 4 | 109
Influenza 4 | 142
Malaria 4 | 140
Meningitis 4 | 46
Peritonitis 4 | 37
Pneumonia 4 | 133
Prostatic Neoplasms 4 | 471
Reperfusion Injury 4 | 84
active Crohn's disease 4 | 918
astrocytoma 4 | 1,493
chronic lymphosyte leukemia 4 | 232
colon cancer 4 | 1,475
nasopharyngeal carcinoma 4 | 1,056
oligodendroglioma 4 | 2,849
pituitary cancer 4 | 1,972
primary pancreatic ductal adenocarcinoma 4 | 1,271
Carcinoma 3 | 2,147
Colorectal Neoplasms 3 | 217
Coronary artery disease 3 | 240
Gastritis 3 | 44
Inflammatory bowel disease 3 | 142
Keratitis 3 | 42
Kidney disease 3 | 396
Leprosy 3 | 77
Liver disease 3 | 219
Melioidosis 3 | 11
Neoplasm Invasiveness 3 | 127
Neurodegenerative disease 3 | 383
Obesity 3 | 616
Pelvic inflammatory disease 3 | 21
Perinatal necrotizing enterocolitis 3 | 18
Tularemia 3 | 22
Waldenstrons macroglobulinemia 3 | 765
adrenocortical carcinoma 3 | 1,427
adult high grade glioma 3 | 2,148
aldosterone-producing adenoma 3 | 664
atypical teratoid/rhabdoid tumor 3 | 1,095
ductal carcinoma in situ 3 | 1,745
limb girdle muscular dystrophy 2A 3 | 156
non-small cell lung cancer 3 | 2,798
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,795
primitive neuroectodermal tumor 3 | 3,031
urothelial carcinoma 3 | 318
Allergic hypersensitivity disease 2 | 123
Atopic dermatitis 2 | 944
Chronic obstructive pulmonary disease 2 | 146
Contact Dermatitis 2 | 80
Endometriosis 2 | 535
Hypertension 2 | 287
Multiple Sclerosis 2 | 498
Vascular disease 2 | 281
chronic rhinosinusitis 2 | 512
hepatocellular carcinoma 2 | 532
inflammatory breast cancer 2 | 404
medulloblastoma 2 | 1,524
pancreatic carcinoma 2 | 567
pterygium 2 | 74

Tissue

Blood and immune system 24 | 17,995
Cardiovascular System 24 | 17,958
Digestive Tract 24 | 18,473
Endocrine System 24 | 18,512
Female tissues 24 | 18,647
Liver and Pancreas 24 | 18,136
Male tissues 24 | 17,969
Nervous System 24 | 18,561
Respiratory system 24 | 17,484
Urinary Tract 24 | 18,444
Skin and soft tissues 23 | 18,115

Target Family

Non-IDG 16 | 11,971
Kinase 6 | 634
Enzyme 1 | 4,146
Transcription Factor 1 | 1,400

PathwayCommons: pid Pathway

Endogenous TLR signaling 24 | 24
Direct p53 effectors 137 | 137
PDGFR-beta signaling pathway 125 | 125
ErbB1 downstream signaling 103 | 103
C-MYB transcription factor net... 87 | 87
CXCR4-mediated signaling event... 87 | 87
Glucocorticoid receptor regula... 85 | 85
Regulation of nuclear SMAD2/3 ... 82 | 82
Regulation of nuclear beta cat... 80 | 80
Signaling events mediated by H... 80 | 80
Validated targets of C-MYC tra... 80 | 80
p73 transcription factor netwo... 80 | 80
E2F transcription factor netwo... 77 | 77
Signaling events mediated by H... 74 | 74
p75(NTR)-mediated signaling 74 | 74
AP-1 transcription factor netw... 71 | 71
CDC42 signaling events 71 | 71
Beta1 integrin cell surface in... 70 | 70
Regulation of Telomerase 70 | 70
TCR signaling in naïve CD4+ T ... 69 | 69
BCR signaling pathway 68 | 68
HIF-1-alpha transcription fact... 67 | 67
Regulation of retinoblastoma p... 67 | 67
Signaling events mediated by V... 67 | 67
Downstream signaling in naïve ... 66 | 66
IL4-mediated signaling events 66 | 66
Integrins in angiogenesis 66 | 66
mTOR signaling pathway 66 | 66
LPA receptor mediated events 65 | 65
Validated nuclear estrogen rec... 65 | 65
Endothelins 64 | 64
Fc-epsilon receptor I signalin... 64 | 64
Neurotrophic factor-mediated T... 63 | 63
Signaling events mediated by f... 63 | 63
Validated targets of C-MYC tra... 63 | 63
IL12-mediated signaling events 62 | 62
Coregulation of Androgen recep... 61 | 61
SHP2 signaling 60 | 60
ATF-2 transcription factor net... 59 | 59
p53 pathway 59 | 59
Notch signaling pathway 58 | 58
Caspase Cascade in Apoptosis 57 | 57
TCR signaling in naïve CD8+ T ... 56 | 56
Thromboxane A2 receptor signal... 56 | 56
FGF signaling pathway 55 | 55
IL2-mediated signaling events 54 | 54
RAC1 signaling pathway 54 | 54
Regulation of Androgen recepto... 54 | 54
Validated transcriptional targ... 54 | 54
Signaling events mediated by P... 53 | 53
Signaling events mediated by S... 53 | 53
TGF-beta receptor signaling 53 | 53
Role of Calcineurin-dependent ... 52 | 52
Angiopoietin receptor Tie2-med... 50 | 50
FoxO family signaling 50 | 50
Posttranslational regulation o... 50 | 50
Ceramide signaling pathway 49 | 49
Hedgehog signaling events medi... 49 | 49
Arf6 trafficking events 48 | 48
Calcineurin-regulated NFAT-dep... 48 | 48
Fanconi anemia pathway 48 | 48
IL6-mediated signaling events 48 | 48
Notch-mediated HES/HEY network 48 | 48
PLK1 signaling events 48 | 48
Regulation of RhoA activity 48 | 48
Validated transcriptional targ... 48 | 48
Insulin Pathway 47 | 47
Class I PI3K signaling events 46 | 46
Integrin-linked kinase signali... 46 | 46
Presenilin action in Notch and... 46 | 46
RhoA signaling pathway 46 | 46
TNF receptor signaling pathway... 46 | 46
a6b1 and a6b4 Integrin signali... 46 | 46
FOXA1 transcription factor net... 45 | 45
FOXA2 and FOXA3 transcription ... 45 | 45
Beta3 integrin cell surface in... 44 | 44
LKB1 signaling events 43 | 43
PAR1-mediated thrombin signali... 43 | 43
Signaling events mediated by H... 43 | 43
Stabilization and expansion of... 43 | 43
BMP receptor signaling 42 | 42
Plasma membrane estrogen recep... 42 | 42
Syndecan-1-mediated signaling ... 42 | 42
Urokinase-type plasminogen act... 42 | 42
ErbB2/ErbB3 signaling events 41 | 41
IFN-gamma pathway 41 | 41
Aurora B signaling 40 | 40
EPHB forward signaling 40 | 40
FOXM1 transcription factor net... 40 | 40
Signaling events mediated by T... 40 | 40
ATR signaling pathway 39 | 39
Regulation of RAC1 activity 39 | 39
Signaling events regulated by ... 39 | 39
CXCR3-mediated signaling event... 38 | 38
GMCSF-mediated signaling event... 38 | 38
Internalization of ErbB1 38 | 38
Syndecan-2-mediated signaling ... 38 | 38
E-cadherin signaling in the na... 37 | 37
IL23-mediated signaling events 37 | 37
Validated transcriptional targ... 37 | 37
CD40/CD40L signaling 36 | 36

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interleukin-1 receptor-associated kinase 1 IRAK1 Tchem Kinase -2.51851 320.4 729
Pulmonary surfactant-associated protein A1 SFTPA1 Tbio Non-IDG -2.01123 102.6 195
Versican core protein VCAN Tbio Non-IDG -2.85549 756.2 159
Transforming protein RhoA RHOA Tbio Enzyme -3.48838 3096.5 467
Toll-like receptor 3 TLR3 Tchem Non-IDG -3.00214 1147.2 751
Lymphocyte antigen 96 LY96 Tbio Non-IDG -2.69962 490.7 314
NF-kappa-B essential modulator IKBKG Tchem Kinase -3.03588 1121.7 849
Inhibitor of nuclear factor kappa-B kinase subunit alpha CHUK Tchem Kinase -2.35199 201.1 1028
TIR domain-containing adapter molecule 1 TICAM1 Tbio Non-IDG -1.44846 31.8 191
Interleukin-1 receptor-associated kinase-like 2 IRAK2 Tbio Kinase -1.48928 31.1 496