Development Level

Tbio 20 | 11,651
Tchem 7 | 1,388
Tclin 4 | 612
Tdark 4 | 6,593

IMPC Phenotype

preweaning lethality, incomple... 4 | 499
decreased total body fat amoun... 3 | 207
abnormal embryo size 2 | 220
embryonic growth retardation 2 | 106
embryonic lethality prior to t... 2 | 278
male infertility 2 | 123
preweaning lethality, complete... 2 | 979
thrombocytopenia 2 | 56
abnormal coat appearance 1 | 31
abnormal forebrain development 1 | 20
abnormal gait 1 | 69
abnormal hindbrain development 1 | 16
abnormal lens morphology 1 | 81
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal vocalization 1 | 21
absent seminal vesicle 1 | 4
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased body length 1 | 101
decreased body weight 1 | 161
decreased circulating insulin ... 1 | 76
decreased prepulse inhibition 1 | 82
decreased vertical activity 1 | 208
enlarged heart 1 | 210
enlarged spleen 1 | 41
female infertility 1 | 60
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating phosphat... 1 | 26
increased mean corpuscular hem... 1 | 96
increased startle reflex 1 | 112
short tibia 1 | 97
small epididymis 1 | 3
small uterus 1 | 3

Disease

Carcinoma 23 | 11,493
ovarian cancer 22 | 8,520
glioblastoma 20 | 5,792
medulloblastoma, large-cell 20 | 6,241
osteosarcoma 20 | 7,950
psoriasis 18 | 6,694
lung cancer 17 | 4,740
Breast cancer 16 | 3,578
lung carcinoma 14 | 2,843
atypical teratoid / rhabdoid tumor 13 | 5,112
group 3 medulloblastoma 13 | 4,104
malignant mesothelioma 13 | 3,232
ependymoma 12 | 4,679
lung adenocarcinoma 12 | 2,716
subependymal giant cell astrocytoma 12 | 2,287
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
primitive neuroectodermal tumor 11 | 3,035
Cancer 10 | 2,499
Schizophrenia 10 | 1,160
adult high grade glioma 10 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
non-small cell lung cancer 10 | 2,890
Astrocytoma, Pilocytic 9 | 3,081
astrocytic glioma 9 | 2,597
invasive ductal carcinoma 9 | 2,951
ulcerative colitis 9 | 1,819
Pick disease 8 | 1,894
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
oligodendroglioma 8 | 2,850
Bipolar Disorder 7 | 666
Intellectual disability 7 | 1,016
Kidney cancer 7 | 2,613
Rheumatoid arthritis 7 | 1,191
pancreatic cancer 7 | 2,398
tuberculosis 7 | 2,010
Depressive disorder 6 | 409
Heart disease 6 | 306
Obesity 6 | 678
breast carcinoma 6 | 1,638
juvenile dermatomyositis 6 | 1,187
pituitary cancer 6 | 1,972
Autosomal recessive predisposition 5 | 1,442
Cognitive delay 5 | 608
Dull intelligence 5 | 645
Global developmental delay 5 | 608
Low intelligence 5 | 645
Major Depressive Disorder 5 | 301
Mental Depression 5 | 333
Mental Retardation 5 | 645
Mental and motor retardation 5 | 608
Mental deficiency 5 | 645
Multiple myeloma 5 | 1,332
Poor school performance 5 | 645
Unipolar Depression 5 | 250
Vascular disease 5 | 319
adrenocortical carcinoma 5 | 1,428
astrocytoma 5 | 1,146
colon cancer 5 | 1,478
cystic fibrosis 5 | 1,696
diabetes mellitus 5 | 1,728
ductal carcinoma in situ 5 | 1,745
interstitial cystitis 5 | 2,312
Brain Ischemia 4 | 110
Cardiomegaly 4 | 116
Cardiomyopathies 4 | 110
Hyperalgesia 4 | 83
Hypertension 4 | 396
Hypertensive disease 4 | 292
Lung Neoplasms 4 | 232
Melanoma 4 | 711
Muscle hypotonia 4 | 571
Seizures 4 | 596
Short stature 4 | 531
Strabismus 4 | 270
esophageal adenocarcinoma 4 | 737
group 4 medulloblastoma 4 | 1,855
non primary Sjogren syndrome sicca 4 | 891
primary pancreatic ductal adenocarcinoma 4 | 1,109
Acquired scoliosis 3 | 281
Arthritis, Juvenile 3 | 126
Byzanthine arch palate 3 | 194
Cardiovascular Diseases 3 | 59
Cocaine-Related Disorders 3 | 92
Concave bridge of nose 3 | 195
Congenital Epicanthus 3 | 177
Coronary artery disease 3 | 268
Curvature of spine 3 | 282
Depressed nasal bridge 3 | 195
Depressed nasal root/bridge 3 | 195
Epilepsy 3 | 792
Essential Hypertension 3 | 94
Juvenile arthritis 3 | 126
Kidney disease 3 | 430
Liver cancer 3 | 604
Neurodegenerative disease 3 | 414
Pectus excavatum 3 | 100
Prostatic Neoplasms 3 | 495
Skin cancer 3 | 469
active Crohn's disease 3 | 922
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962

Tissue

Blood and immune system 35 | 16,909
Digestive Tract 35 | 17,369
Endocrine System 35 | 18,159
Female tissues 35 | 17,400
Liver and Pancreas 35 | 16,750
Male tissues 35 | 17,142
Nervous System 35 | 16,725
Respiratory system 35 | 16,393
Skin and soft tissues 35 | 17,230
Urinary Tract 35 | 16,678
Cardiovascular System 34 | 15,192

Target Family

Non-IDG 16 | 12,091
Kinase 10 | 634
Enzyme 3 | 4,145
Ion Channel 3 | 344
Transcription Factor 2 | 1,400
GPCR 1 | 408

PathwayCommons: panther Pathway

http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 264 | 264
http://identifiers.org/panther... 197 | 197
http://identifiers.org/panther... 164 | 164
http://identifiers.org/panther... 151 | 151
http://identifiers.org/panther... 150 | 150
http://identifiers.org/panther... 149 | 149
http://identifiers.org/panther... 146 | 146
http://identifiers.org/panther... 124 | 124
http://identifiers.org/panther... 118 | 118
http://identifiers.org/panther... 116 | 116
http://identifiers.org/panther... 115 | 115
http://identifiers.org/panther... 110 | 110
http://identifiers.org/panther... 107 | 107
http://identifiers.org/panther... 104 | 104
http://identifiers.org/panther... 91 | 91
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 86 | 86
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 67 | 67
http://identifiers.org/panther... 65 | 65
http://identifiers.org/panther... 63 | 63
http://identifiers.org/panther... 61 | 61
http://identifiers.org/panther... 60 | 60
http://identifiers.org/panther... 56 | 56
http://identifiers.org/panther... 54 | 54
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 51 | 51
http://identifiers.org/panther... 47 | 47
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 44 | 44
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 41 | 41
http://identifiers.org/panther... 38 | 38
http://identifiers.org/panther... 37 | 37
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 33 | 33
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 31 | 31
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 27 | 27
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 17 | 17
http://identifiers.org/panther... 16 | 16
http://identifiers.org/panther... 15 | 15
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 13 | 13
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 8 | 8
http://identifiers.org/panther... 8 | 8

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 PLCB1 Tbio Enzyme -2.50444 332.8 190
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 GNB3 Tbio Non-IDG -2.34836 235.8 161
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 GNG3 Tdark Non-IDG -0.61010 4.53 48
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 GNG4 Tdark Non-IDG -0.35486 2.45 58
Beta-arrestin-1 ARRB1 Tbio Non-IDG -2.63877 418.5 490
Mitogen-activated protein kinase 3 MAPK3 Tchem Kinase -3.66226 3484.0 1440
Angiotensinogen AGT Tbio Non-IDG -3.24591 1711.3 695
Mitogen-activated protein kinase 1 MAPK1 Tchem Kinase -3.18822 1239.4 1248
Beta-adrenergic receptor kinase 1 GRK2 Tchem Kinase -2.61043 428.8 455
Dual specificity mitogen-activated protein kinase kinase 2 MAP2K2 Tclin Kinase -1.83744 60.9 883