Development Level

Tbio 21 | 11,445
Tchem 7 | 1,598
Tclin 4 | 613
Tdark 3 | 6,588

Collection

Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

abnormal behavior 4 | 298
hyperactivity 4 | 148
decreased bone mineral content 2 | 151
decreased fasted circulating g... 2 | 65
increased circulating triglyce... 2 | 42
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal spleen morphology 1 | 55
decreased circulating chloride... 1 | 30
decreased circulating iron lev... 1 | 32
decreased grip strength 1 | 116
decreased neutrophil cell numb... 1 | 42
decreased respiratory quotient 1 | 16
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
enlarged epididymis 1 | 31
enlarged heart 1 | 210
enlarged spleen 1 | 41
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased circulating alanine ... 1 | 13
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased circulating sodium l... 1 | 71
limb grasping 1 | 41
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 24 | 11,493
glioblastoma 22 | 5,792
medulloblastoma, large-cell 21 | 6,241
atypical teratoid / rhabdoid tumor 20 | 5,112
ependymoma 19 | 4,679
osteosarcoma 18 | 7,950
ovarian cancer 18 | 8,520
primitive neuroectodermal tumor 18 | 3,035
psoriasis 18 | 6,694
adult high grade glioma 17 | 3,801
group 3 medulloblastoma 17 | 4,104
Astrocytoma, Pilocytic 16 | 3,081
oligodendroglioma 15 | 2,850
lung carcinoma 13 | 2,843
subependymal giant cell astrocytoma 13 | 2,287
Breast cancer 12 | 3,578
astrocytic glioma 12 | 2,597
Kidney cancer 10 | 2,613
invasive ductal carcinoma 9 | 2,951
pancreatic cancer 9 | 2,398
lung cancer 8 | 4,740
Depressive disorder 7 | 409
interstitial cystitis 7 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
malignant mesothelioma 7 | 3,232
non-small cell lung cancer 7 | 2,890
pituitary cancer 7 | 1,972
Carney complex 6 | 25
Pick disease 6 | 1,894
Schizophrenia 6 | 1,160
astrocytoma 6 | 1,146
lung adenocarcinoma 6 | 2,716
ulcerative colitis 6 | 1,819
Bipolar Disorder 5 | 666
Duchenne muscular dystrophy 5 | 601
Epilepsy 5 | 792
Intellectual disability 5 | 1,016
Mental Depression 5 | 333
breast carcinoma 5 | 1,638
diabetes mellitus 5 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
juvenile dermatomyositis 5 | 1,187
Alcoholic Intoxication, Chronic 4 | 289
Autosomal recessive predisposition 4 | 1,442
Hyperactive behavior 4 | 91
Hypertensive disease 4 | 292
Major Depressive Disorder 4 | 301
Primary pigmented nodular adrenocortical disease 4 | 13
Substance Withdrawal Syndrome 4 | 55
Unipolar Depression 4 | 250
Waldenstrons macroglobulinemia 4 | 765
acute quadriplegic myopathy 4 | 1,158
colon cancer 4 | 1,478
group 4 medulloblastoma 4 | 1,855
medulloblastoma 4 | 720
non primary Sjogren syndrome sicca 4 | 891
primary pancreatic ductal adenocarcinoma 4 | 1,109
tuberculosis 4 | 2,010
Acquired metabolic disease 3 | 336
Anxiety 3 | 136
Anxiety disease 3 | 113
Autistic Disorder 3 | 364
Dystonia 3 | 164
Hyperkinesis 3 | 32
Liver cancer 3 | 604
Mood Disorders 3 | 184
Multiple myeloma 3 | 1,332
Muscle Weakness 3 | 170
Neurodegenerative disease 3 | 414
Neuropathy 3 | 261
Obesity 3 | 678
Osteoporosis 3 | 363
Rheumatoid arthritis 3 | 1,191
active Crohn's disease 3 | 922
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
cutaneous lupus erythematosus 3 | 1,057
ductal carcinoma in situ 3 | 1,745
pancreatic carcinoma 3 | 562
sarcoidosis 3 | 370
Arthritis, Juvenile 2 | 126
Cushing's syndrome 2 | 48
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Diabetes Mellitus, Type 2 2 | 142
Dysarthria 2 | 192
Dystonic disease 2 | 106
Hypertension 2 | 396
Increased susceptibility to fractures 2 | 21
Juvenile arthritis 2 | 126
Melanoma 2 | 711
Neurogenic Muscular Atrophy 2 | 139
Parkinson's disease 2 | 392
Progressive disorder 2 | 142
Psychotic Disorders 2 | 151
Skin cancer 2 | 469
cystic fibrosis 2 | 1,696
dermatomyositis 2 | 966
muscle degeneration 2 | 139
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pediatric high grade glioma 2 | 1,064

Tissue

Endocrine System 35 | 18,159
Male tissues 35 | 17,142
Blood and immune system 34 | 16,909
Digestive Tract 34 | 17,369
Female tissues 34 | 17,400
Liver and Pancreas 34 | 16,750
Nervous System 34 | 16,725
Skin and soft tissues 34 | 17,230
Respiratory system 33 | 16,393
Urinary Tract 33 | 16,678
Cardiovascular System 32 | 15,192

Target Family

Non-IDG 14 | 12,091
Enzyme 12 | 4,145
Ion Channel 4 | 344
Kinase 3 | 634
GPCR 2 | 408

PathwayCommons: panther Pathway

http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 264 | 264
http://identifiers.org/panther... 197 | 197
http://identifiers.org/panther... 164 | 164
http://identifiers.org/panther... 151 | 151
http://identifiers.org/panther... 150 | 150
http://identifiers.org/panther... 149 | 149
http://identifiers.org/panther... 146 | 146
http://identifiers.org/panther... 124 | 124
http://identifiers.org/panther... 118 | 118
http://identifiers.org/panther... 116 | 116
http://identifiers.org/panther... 115 | 115
http://identifiers.org/panther... 110 | 110
http://identifiers.org/panther... 107 | 107
http://identifiers.org/panther... 104 | 104
http://identifiers.org/panther... 91 | 91
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 86 | 86
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 67 | 67
http://identifiers.org/panther... 65 | 65
http://identifiers.org/panther... 63 | 63
http://identifiers.org/panther... 61 | 61
http://identifiers.org/panther... 60 | 60
http://identifiers.org/panther... 56 | 56
http://identifiers.org/panther... 54 | 54
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 51 | 51
http://identifiers.org/panther... 47 | 47
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 44 | 44
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 41 | 41
http://identifiers.org/panther... 38 | 38
http://identifiers.org/panther... 37 | 37
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 33 | 33
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 31 | 31
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 27 | 27
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 17 | 17
http://identifiers.org/panther... 16 | 16
http://identifiers.org/panther... 15 | 15
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 13 | 13
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 8 | 8
http://identifiers.org/panther... 8 | 8

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adenylate cyclase type 8 ADCY8 Tbio Enzyme -2.04645 112.4 147
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 GNG8 Tdark Non-IDG -2.17483 154.8 34
Voltage-dependent T-type calcium channel subunit alpha-1G CACNA1G Tclin Ion Channel -2.16668 140.8 217
Adenylate cyclase type 7 ADCY7 Tbio Enzyme -1.68806 49.1 114
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 GNG5 Tbio Non-IDG -0.57807 4.05 87
Adenylate cyclase type 6 ADCY6 Tchem Enzyme -2.05332 113.7 111
Adenylate cyclase type 1 ADCY1 Tchem Enzyme -1.61657 45.3 134
Voltage-dependent N-type calcium channel subunit alpha-1B CACNA1B Tclin Ion Channel -2.24422 170.7 75
G protein-activated inward rectifier potassium channel 1 KCNJ3 Tchem Ion Channel -2.34432 217.2 267
Gamma-aminobutyric acid type B receptor subunit 2 GABBR2 Tclin GPCR -1.97367 92.4 395