Development Level

Tchem 28 | 1,598
Tbio 13 | 11,445
Tclin 2 | 613

Collection

Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

decreased body weight 3 | 161
preweaning lethality, complete... 3 | 979
preweaning lethality, incomple... 3 | 499
abnormal bone mineralization 2 | 38
decreased circulating creatini... 2 | 39
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
increased total body fat amoun... 2 | 134
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal glucose homeostasis 1 | 4
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal lung morphology 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal spinal cord morpholog... 1 | 9
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating triglyce... 1 | 79
decreased grip strength 1 | 116
embryonic growth retardation 1 | 106
enlarged epididymis 1 | 31
enlarged heart 1 | 210
enlarged heart atrium 1 | 4
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
increased bone mineral density 1 | 72
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating glucose ... 1 | 24
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased startle reflex 1 | 112
mammalian phenotype 1 | 17
prenatal lethality 1 | 28
short tibia 1 | 97
small seminal vesicle 1 | 10
small testis 1 | 58
thrombocytosis 1 | 27

Disease

Carcinoma 36 | 11,493
Cancer 33 | 2,499
osteosarcoma 30 | 7,950
ovarian cancer 30 | 8,520
medulloblastoma, large-cell 27 | 6,241
glioblastoma 25 | 5,792
lung cancer 25 | 4,740
atypical teratoid / rhabdoid tumor 23 | 5,112
Breast cancer 22 | 3,578
psoriasis 21 | 6,694
Kidney cancer 16 | 2,613
adult high grade glioma 16 | 3,801
ependymoma 15 | 4,679
Lung Neoplasms 14 | 232
Breast Neoplasms 13 | 445
group 3 medulloblastoma 13 | 4,104
juvenile dermatomyositis 13 | 1,187
Epilepsy 12 | 792
Mammary Neoplasms 12 | 425
Schizophrenia 12 | 1,160
Seizures 12 | 596
primitive neuroectodermal tumor 12 | 3,035
Carcinoma, Hepatocellular 11 | 228
Intellectual disability 11 | 1,016
Liver carcinoma 11 | 240
astrocytic glioma 11 | 2,597
invasive ductal carcinoma 11 | 2,951
subependymal giant cell astrocytoma 11 | 2,287
Astrocytoma, Pilocytic 10 | 3,081
Dull intelligence 10 | 645
Endometrial cancer 10 | 311
Hypoplastic mandible condyle 10 | 275
Low intelligence 10 | 645
Mandibular hypoplasia 10 | 275
Melanoma 10 | 711
Mental Retardation 10 | 645
Mental deficiency 10 | 645
Micrognathism 10 | 275
Poor school performance 10 | 645
Prostatic Neoplasms 10 | 495
Stomach Neoplasms 10 | 300
adrenocortical carcinoma 10 | 1,428
breast carcinoma 10 | 1,638
malignant mesothelioma 10 | 3,232
non-small cell lung cancer 10 | 2,890
pancreatic cancer 10 | 2,398
ulcerative colitis 10 | 1,819
Adenoma 9 | 167
Autosomal recessive predisposition 9 | 1,442
Neoplasm Metastasis 9 | 168
Orbital separation excessive 9 | 244
Squamous cell carcinoma 9 | 129
acute quadriplegic myopathy 9 | 1,158
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
lung adenocarcinoma 9 | 2,716
oligodendroglioma 9 | 2,850
Bladder Neoplasm 8 | 112
Carcinoma, Squamous Cell 8 | 110
Concave bridge of nose 8 | 195
DOID:2627 8 | 94
Depressed nasal bridge 8 | 195
Depressed nasal root/bridge 8 | 195
Liver cancer 8 | 604
Lymphoid leukemia 8 | 160
Ovarian Neoplasms 8 | 102
Pancreatic Neoplasm 8 | 85
Pancreatic Neoplasms 8 | 85
Short stature 8 | 531
Skin cancer 8 | 469
Transitional cell carcinoma of bladder 8 | 17
Urinary Bladder Neoplasms 8 | 114
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
nasopharyngeal carcinoma 8 | 1,058
Abnormality of metabolism/homeostasis 7 | 134
Adenocarcinoma 7 | 122
Big calvaria 7 | 147
Blepharoptosis 7 | 231
Byzanthine arch palate 7 | 194
Cognitive delay 7 | 608
Colorectal Neoplasms 7 | 243
Downward slant of palpebral fissure 7 | 158
Frontal bossing 7 | 157
Global developmental delay 7 | 608
Immune system cancer 7 | 140
Increased head circumference 7 | 147
Increased size of cranium 7 | 147
Increased size of skull 7 | 147
Isolated cases 7 | 72
Melanocytic nevus 7 | 43
Mental and motor retardation 7 | 608
Muscle hypotonia 7 | 571
Noncancerous mole 7 | 28
Splenomegaly 7 | 190
Strabismus 7 | 270
Vascular disease 7 | 319
diabetes mellitus 7 | 1,728
interstitial cystitis 7 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
medulloblastoma 7 | 720
ovarian neoplasm 7 | 99

Tissue

Endocrine System 42 | 18,159
Female tissues 42 | 17,400
Blood and immune system 41 | 16,909
Digestive Tract 41 | 17,369
Liver and Pancreas 41 | 16,750
Male tissues 41 | 17,142
Nervous System 41 | 16,725
Respiratory system 41 | 16,393
Skin and soft tissues 41 | 17,230
Urinary Tract 41 | 16,678
Cardiovascular System 39 | 15,192

Target Family

Kinase 20 | 634
Enzyme 12 | 4,145
Non-IDG 7 | 12,091
Transcription Factor 4 | 1,400

PathwayCommons: panther Pathway

http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 264 | 264
http://identifiers.org/panther... 197 | 197
http://identifiers.org/panther... 164 | 164
http://identifiers.org/panther... 151 | 151
http://identifiers.org/panther... 150 | 150
http://identifiers.org/panther... 149 | 149
http://identifiers.org/panther... 146 | 146
http://identifiers.org/panther... 124 | 124
http://identifiers.org/panther... 118 | 118
http://identifiers.org/panther... 116 | 116
http://identifiers.org/panther... 115 | 115
http://identifiers.org/panther... 110 | 110
http://identifiers.org/panther... 107 | 107
http://identifiers.org/panther... 104 | 104
http://identifiers.org/panther... 91 | 91
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 86 | 86
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 67 | 67
http://identifiers.org/panther... 65 | 65
http://identifiers.org/panther... 63 | 63
http://identifiers.org/panther... 61 | 61
http://identifiers.org/panther... 60 | 60
http://identifiers.org/panther... 56 | 56
http://identifiers.org/panther... 54 | 54
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 51 | 51
http://identifiers.org/panther... 47 | 47
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 44 | 44
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 41 | 41
http://identifiers.org/panther... 38 | 38
http://identifiers.org/panther... 37 | 37
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 33 | 33
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 31 | 31
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 27 | 27
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 17 | 17
http://identifiers.org/panther... 16 | 16
http://identifiers.org/panther... 15 | 15
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 13 | 13
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 8 | 8
http://identifiers.org/panther... 8 | 8

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine/threonine-protein kinase ATR ATR Tchem Kinase -2.80362 549.6 376
GTPase KRas KRAS Tchem Enzyme -3.80300 6069.9 574
GTPase HRas HRAS Tchem Enzyme -4.01300 9975.8 492
GTPase NRas NRAS Tchem Enzyme -3.01534 959.1 328
Tumor protein p73 TP73 Tbio Transcription Factor -1.92832 82.6 708
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta PIK3C2B Tchem Kinase -1.50611 34.7 157
Retinoblastoma-associated protein RB1 Tchem Non-IDG -3.07052 1137.4 2150
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma PIK3C2G Tchem Kinase -0.96984 8.60 87
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha PIK3C2A Tchem Kinase -3.50398 3129.0 525
Putative tyrosine-protein phosphatase TPTE TPTE Tbio Enzyme -2.11875 127.6 234