Development Level

Tbio 3 | 11,445

IMPC Phenotype

embryonic lethality prior to t... 1 | 278
prenatal lethality prior to he... 1 | 87
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 3 | 11,493
ovarian cancer 3 | 8,520
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
Autosomal recessive predisposition 2 | 1,442
Breast cancer 2 | 3,578
Cardiomyopathies 2 | 110
Cognitive delay 2 | 608
Comatose 2 | 56
Decreased platelet count 2 | 111
Dehydration 2 | 40
Dull intelligence 2 | 645
Dystonia 2 | 164
Dystonic disease 2 | 106
Epilepsy 2 | 792
Failure to gain weight 2 | 365
Global developmental delay 2 | 608
Hepatomegaly 2 | 285
Hyperammonemia 2 | 30
Hyperglycinemia 2 | 6
Intellectual disability 2 | 1,016
Lethargy 2 | 77
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Metabolic acidosis 2 | 90
Methylmalonic acidemia 2 | 37
Multiple myeloma 2 | 1,332
Pancreatitis 2 | 123
Pediatric failure to thrive 2 | 365
Poor school performance 2 | 645
Propionic acidemia 2 | 16
Thrombocytopenia 2 | 197
Vomiting 2 | 116
lung adenocarcinoma 2 | 2,716
lung cancer 2 | 4,740
3-Methylcrotonyl-CoA carboxylase deficiency 1 | 11
Abnormality of immune system physiology 1 | 16
Acidosis, Lactic 1 | 97
Acute encephalopathy 1 | 4
Anemia 1 | 365
Anorexia 1 | 43
Atherosclerosis 1 | 291
Axial hypotonia 1 | 46
Biotinidase deficiency 1 | 14
Cardiac Arrhythmia 1 | 103
Cardiac conduction abnormalities 1 | 78
Cerebral atrophy 1 | 178
Chemical and Drug Induced Liver Injury 1 | 195
Chronic kidney disease stage 5 1 | 31
Conduction disorder of the heart 1 | 79
Constipation 1 | 181
Degenerative brain disorder 1 | 100
Disease of metabolism 1 | 18
Dysarthria 1 | 192
Dyschezia 1 | 135
EKG abnormalities 1 | 78
Eczema 1 | 45
Electrocardiogram abnormal 1 | 81
Electrocardiogram change 1 | 78
Growth delay 1 | 114
Growth failure 1 | 114
Growth retardation 1 | 115
HYPERGLYCINURIA (disorder) 1 | 12
Hemoglobin low 1 | 124
Homocystinuria 1 | 21
Hypoglycemia 1 | 152
Immunologic Deficiency Syndromes 1 | 113
Inborn Errors of Metabolism 1 | 16
L-2-hydroxyglutaric aciduria 1 | 8
Lactic acidemia 1 | 95
Leukopenia 1 | 72
Limb hypertonia 1 | 5
Liver cancer 1 | 604
Melanoma 1 | 711
Metabolic Ketosis 1 | 3
Methylmalonic aciduria 1 | 9
Nausea and vomiting 1 | 97
Nephritis, Tubulointerstitial 1 | 8
Neutrophil count decreased 1 | 47
Organic aciduria 1 | 6
Osteoporosis 1 | 363
Pancytopenia 1 | 45
Poor growth 1 | 114
Respiratory distress 1 | 43
Seizures 1 | 596
Supratentorial atrophy 1 | 94
Tachypnea 1 | 20
Very poor growth 1 | 114
Vitamin B12 deficiency 1 | 20
breast carcinoma 1 | 1,638
ductal carcinoma in situ 1 | 1,745
glioblastoma 1 | 5,792
invasive ductal carcinoma 1 | 2,951
lung carcinoma 1 | 2,843
non-small cell lung cancer 1 | 2,890
osteosarcoma 1 | 7,950
progressive supranuclear palsy 1 | 676
psoriasis 1 | 6,694
ulcerative colitis 1 | 1,819

Tissue

Blood and immune system 3 | 16,909
Cardiovascular System 3 | 15,192
Digestive Tract 3 | 17,369
Endocrine System 3 | 18,159
Female tissues 3 | 17,400
Liver and Pancreas 3 | 16,750
Male tissues 3 | 17,142
Nervous System 3 | 16,725
Respiratory system 3 | 16,393
Skin and soft tissues 3 | 17,230
Urinary Tract 3 | 16,678

Target Family

Enzyme 3 | 4,145

PathwayCommons: panther Pathway

http://identifiers.org/panther... 3 | 3
http://identifiers.org/panther... 264 | 264
http://identifiers.org/panther... 197 | 197
http://identifiers.org/panther... 164 | 164
http://identifiers.org/panther... 151 | 151
http://identifiers.org/panther... 150 | 150
http://identifiers.org/panther... 149 | 149
http://identifiers.org/panther... 146 | 146
http://identifiers.org/panther... 124 | 124
http://identifiers.org/panther... 118 | 118
http://identifiers.org/panther... 116 | 116
http://identifiers.org/panther... 115 | 115
http://identifiers.org/panther... 110 | 110
http://identifiers.org/panther... 107 | 107
http://identifiers.org/panther... 104 | 104
http://identifiers.org/panther... 91 | 91
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 86 | 86
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 67 | 67
http://identifiers.org/panther... 65 | 65
http://identifiers.org/panther... 63 | 63
http://identifiers.org/panther... 61 | 61
http://identifiers.org/panther... 60 | 60
http://identifiers.org/panther... 56 | 56
http://identifiers.org/panther... 54 | 54
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 51 | 51
http://identifiers.org/panther... 47 | 47
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 44 | 44
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 41 | 41
http://identifiers.org/panther... 38 | 38
http://identifiers.org/panther... 37 | 37
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 33 | 33
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 31 | 31
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 27 | 27
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 17 | 17
http://identifiers.org/panther... 16 | 16
http://identifiers.org/panther... 15 | 15
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 13 | 13
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 8 | 8
http://identifiers.org/panther... 8 | 8

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ethylmalonyl-CoA decarboxylase ECHDC1 Tbio Enzyme -2.16398 143.2 102
Methylmalonyl-CoA mutase, mitochondrial MUT Tbio Enzyme -2.51690 305.3 99
Propionyl-CoA carboxylase beta chain, mitochondrial PCCB Tbio Enzyme -1.77648 58.9 136