Development Level

Tbio 3 | 11,445

IMPC Phenotype

abnormal behavior 1 | 298
decreased granulocyte number 1 | 6
decreased prepulse inhibition 1 | 82
increased startle reflex 1 | 112
preweaning lethality, complete... 1 | 979

Disease

osteosarcoma 3 | 7,950
Autosomal recessive predisposition 2 | 1,442
Down syndrome 2 | 499
Homocystinuria 2 | 21
Hypermethioninemia 2 | 11
group 4 medulloblastoma 2 | 1,855
hepatocellular carcinoma 2 | 547
medulloblastoma, large-cell 2 | 6,241
pancreatic cancer 2 | 2,398
progressive supranuclear palsy 2 | 676
psoriasis 2 | 6,694
Acute maxillary sinusitis 1 | 2
Adverse reaction to drug 1 | 61
Alcoholic Intoxication 1 | 34
Alzheimer's disease 1 | 658
Amino Acid Metabolism, Inborn Errors 1 | 13
Anemia 1 | 365
Anemia, Megaloblastic 1 | 16
Bipolar Disorder 1 | 666
Brain Diseases 1 | 24
Breast Neoplasms 1 | 445
COPD 1 | 118
Cancer 1 | 2,499
Carcinoma, Hepatocellular 1 | 228
Cataract 4 multiple types 1 | 14
Central nervous system demyelination 1 | 28
Cerebral atrophy 1 | 178
Cognitive delay 1 | 608
Decreased methionine synthase activity 1 | 4
Decreased methylcobalamin 1 | 4
Degenerative brain disorder 1 | 100
Demyelinating Diseases 1 | 7
Depressive disorder 1 | 409
Diabetes Mellitus, Non-Insulin-Dependent 1 | 145
Diabetes Mellitus, Type 2 1 | 142
Drug-Related Side Effects and Adverse Reactions 1 | 62
Dull intelligence 1 | 645
Dyskeratosis congenita 1 | 24
Dystonia 1 | 164
Dystonic disease 1 | 106
Epilepsy 1 | 792
Failure to gain weight 1 | 365
Fatty Liver 1 | 70
Feeding difficulties in infancy 1 | 175
Gait abnormality 1 | 135
Gastrointestinal Diseases 1 | 12
Global developmental delay 1 | 608
Hematologic Diseases 1 | 8
Hematological Disease 1 | 18
Hepatic methionine adenosyltransferase deficiency 1 | 7
Hyperhomocysteinemia 1 | 37
Hyperhomocystinemia 1 | 6
Hyperplasia 1 | 27
Hyperreflexia 1 | 209
Hypomethioninemia 1 | 4
Infantile onset 1 | 238
Infertility, Male 1 | 46
Leukoencephalopathies 1 | 29
Liver carcinoma 1 | 240
Low intelligence 1 | 645
Lymphoma 1 | 81
Lymphoma, Follicular 1 | 18
Male infertility 1 | 206
Malnutrition 1 | 11
Mammary Neoplasms 1 | 425
Mental Depression 1 | 333
Mental Retardation 1 | 645
Mental and motor retardation 1 | 608
Mental deficiency 1 | 645
Methylcobalamin Deficiency, CblG Type 1 | 1
Methylmalonic acidemia 1 | 37
Muscle hypotonia 1 | 571
Neural tube defect, folate-sensitive 1 | 4
OROFACIAL CLEFT 1 1 | 2
Ophthalmia neonatorum 1 | 3
Pediatric failure to thrive 1 | 365
Peripheral demyelination 1 | 16
Pick disease 1 | 1,894
Poor coordination 1 | 11
Poor school performance 1 | 645
Schizophrenia 1 | 1,160
Seizures 1 | 596
Severe depression 1 | 5
Supratentorial atrophy 1 | 94
Vitamin B12 deficiency 1 | 20
Waldenstrons macroglobulinemia 1 | 765
acute quadriplegic myopathy 1 | 1,158
astrocytic glioma 1 | 2,597
chronic rhinosinusitis 1 | 512
dermatomyositis 1 | 966
glioblastoma 1 | 5,792
lung adenocarcinoma 1 | 2,716
non-small cell lung cancer 1 | 2,890
oligodendroglioma 1 | 2,850
ovarian cancer 1 | 8,520
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
pediatric high grade glioma 1 | 1,064
primary pancreatic ductal adenocarcinoma 1 | 1,109
primitive neuroectodermal tumor 1 | 3,035
spina bifida 1 | 1,074

Tissue

Blood and immune system 3 | 16,909
Cardiovascular System 3 | 15,192
Digestive Tract 3 | 17,369
Endocrine System 3 | 18,159
Female tissues 3 | 17,400
Liver and Pancreas 3 | 16,750
Male tissues 3 | 17,142
Nervous System 3 | 16,725
Respiratory system 3 | 16,393
Skin and soft tissues 3 | 17,230
Urinary Tract 3 | 16,678

Target Family

Enzyme 3 | 4,145

PathwayCommons: panther Pathway

http://identifiers.org/panther... 3 | 3
http://identifiers.org/panther... 264 | 264
http://identifiers.org/panther... 197 | 197
http://identifiers.org/panther... 164 | 164
http://identifiers.org/panther... 151 | 151
http://identifiers.org/panther... 150 | 150
http://identifiers.org/panther... 149 | 149
http://identifiers.org/panther... 146 | 146
http://identifiers.org/panther... 124 | 124
http://identifiers.org/panther... 118 | 118
http://identifiers.org/panther... 116 | 116
http://identifiers.org/panther... 115 | 115
http://identifiers.org/panther... 110 | 110
http://identifiers.org/panther... 107 | 107
http://identifiers.org/panther... 104 | 104
http://identifiers.org/panther... 91 | 91
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 86 | 86
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 67 | 67
http://identifiers.org/panther... 65 | 65
http://identifiers.org/panther... 63 | 63
http://identifiers.org/panther... 61 | 61
http://identifiers.org/panther... 60 | 60
http://identifiers.org/panther... 56 | 56
http://identifiers.org/panther... 54 | 54
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 51 | 51
http://identifiers.org/panther... 47 | 47
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 44 | 44
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 41 | 41
http://identifiers.org/panther... 38 | 38
http://identifiers.org/panther... 37 | 37
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 33 | 33
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 31 | 31
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 27 | 27
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 17 | 17
http://identifiers.org/panther... 16 | 16
http://identifiers.org/panther... 15 | 15
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 13 | 13
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 8 | 8
http://identifiers.org/panther... 8 | 8

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Methionine synthase MTR Tbio Enzyme -2.56900 300.2 87
S-adenosylmethionine synthase isoform type-2 MAT2A Tbio Enzyme -1.91969 84.1 242
S-adenosylmethionine synthase isoform type-1 MAT1A Tbio Enzyme -2.11527 125.3 167