Development Level

Tbio 4 | 11,445

IMPC Phenotype

embryonic lethality prior to t... 1 | 278
prenatal lethality prior to he... 1 | 87
preweaning lethality, complete... 1 | 979

Disease

ovarian cancer 4 | 8,520
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Autosomal recessive predisposition 3 | 1,442
Carcinoma 3 | 11,493
Cardiomyopathies 3 | 110
Cognitive delay 3 | 608
Comatose 3 | 56
Decreased platelet count 3 | 111
Dehydration 3 | 40
Dull intelligence 3 | 645
Dystonia 3 | 164
Dystonic disease 3 | 106
Failure to gain weight 3 | 365
Global developmental delay 3 | 608
Hepatomegaly 3 | 285
Hyperammonemia 3 | 30
Hyperglycinemia 3 | 6
Intellectual disability 3 | 1,016
Lethargy 3 | 77
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental and motor retardation 3 | 608
Mental deficiency 3 | 645
Metabolic acidosis 3 | 90
Methylmalonic acidemia 3 | 37
Pancreatitis 3 | 123
Pediatric failure to thrive 3 | 365
Poor school performance 3 | 645
Propionic acidemia 3 | 16
Thrombocytopenia 3 | 197
Vomiting 3 | 116
lung cancer 3 | 4,740
Abnormality of immune system physiology 2 | 16
Acidosis, Lactic 2 | 97
Acute encephalopathy 2 | 4
Anemia 2 | 365
Apnea 2 | 45
Axial hypotonia 2 | 46
Cardiac Arrhythmia 2 | 103
Cardiac conduction abnormalities 2 | 78
Cerebral atrophy 2 | 178
Conduction disorder of the heart 2 | 79
Constipation 2 | 181
Decrease in appetite 2 | 8
Degenerative brain disorder 2 | 100
Dyschezia 2 | 135
EKG abnormalities 2 | 78
Eczema 2 | 45
Electrocardiogram abnormal 2 | 81
Electrocardiogram change 2 | 78
Epilepsy 2 | 792
Feeding difficulties in infancy 2 | 175
Glycinuria 2 | 10
HYPERGLYCINURIA (disorder) 2 | 12
Hemoglobin low 2 | 124
Hypoglycemia 2 | 152
Lactic acidemia 2 | 95
Limb hypertonia 2 | 5
Neutrophil count decreased 2 | 47
Organic aciduria 2 | 6
Osteoporosis 2 | 363
Pancytopenia 2 | 45
Propionic acidemia, type II 2 | 2
Seizures 2 | 596
Short stature 2 | 531
Supratentorial atrophy 2 | 94
Tachypnea 2 | 20
adrenocortical carcinoma 2 | 1,428
glioblastoma 2 | 5,792
osteosarcoma 2 | 7,950
3-Methylcrotonyl-CoA carboxylase deficiency 1 | 11
Atherosclerosis 1 | 291
Breast cancer 1 | 3,578
Cholangiocarcinoma 1 | 35
Disease of metabolism 1 | 18
Dysarthria 1 | 192
Growth delay 1 | 114
Growth failure 1 | 114
Growth retardation 1 | 115
Homocystinuria 1 | 21
Immunologic Deficiency Syndromes 1 | 113
Kidney cancer 1 | 2,613
Leukopenia 1 | 72
Liver cancer 1 | 604
Multiple myeloma 1 | 1,332
Nausea and vomiting 1 | 97
Pick disease 1 | 1,894
Poor growth 1 | 114
Refractive error 1 | 50
Respiratory distress 1 | 43
Very poor growth 1 | 114
Vitamin B12 deficiency 1 | 20
interstitial cystitis 1 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
lung adenocarcinoma 1 | 2,716
lung carcinoma 1 | 2,843
non-small cell lung cancer 1 | 2,890
psoriasis 1 | 6,694
tuberculosis 1 | 2,010
ulcerative colitis 1 | 1,819

Tissue

Blood and immune system 4 | 16,909
Cardiovascular System 4 | 15,192
Digestive Tract 4 | 17,369
Endocrine System 4 | 18,159
Female tissues 4 | 17,400
Liver and Pancreas 4 | 16,750
Male tissues 4 | 17,142
Nervous System 4 | 16,725
Respiratory system 4 | 16,393
Skin and soft tissues 4 | 17,230
Urinary Tract 4 | 16,678

Target Family

Enzyme 4 | 4,145

PathwayCommons: panther Pathway

http://identifiers.org/panther... 4 | 4
http://identifiers.org/panther... 264 | 264
http://identifiers.org/panther... 197 | 197
http://identifiers.org/panther... 164 | 164
http://identifiers.org/panther... 151 | 151
http://identifiers.org/panther... 150 | 150
http://identifiers.org/panther... 149 | 149
http://identifiers.org/panther... 146 | 146
http://identifiers.org/panther... 124 | 124
http://identifiers.org/panther... 118 | 118
http://identifiers.org/panther... 116 | 116
http://identifiers.org/panther... 115 | 115
http://identifiers.org/panther... 110 | 110
http://identifiers.org/panther... 107 | 107
http://identifiers.org/panther... 104 | 104
http://identifiers.org/panther... 91 | 91
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 86 | 86
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 67 | 67
http://identifiers.org/panther... 65 | 65
http://identifiers.org/panther... 63 | 63
http://identifiers.org/panther... 61 | 61
http://identifiers.org/panther... 60 | 60
http://identifiers.org/panther... 56 | 56
http://identifiers.org/panther... 54 | 54
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 51 | 51
http://identifiers.org/panther... 47 | 47
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 44 | 44
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 41 | 41
http://identifiers.org/panther... 38 | 38
http://identifiers.org/panther... 37 | 37
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 33 | 33
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 31 | 31
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 27 | 27
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 17 | 17
http://identifiers.org/panther... 16 | 16
http://identifiers.org/panther... 15 | 15
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 13 | 13
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 8 | 8
http://identifiers.org/panther... 8 | 8

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Methylmalonyl-CoA epimerase, mitochondrial MCEE Tbio Enzyme -1.05059 11.7 115
Methylmalonyl-CoA mutase, mitochondrial MUT Tbio Enzyme -2.51690 305.3 99
Propionyl-CoA carboxylase alpha chain, mitochondrial PCCA Tbio Enzyme -2.12940 126.6 118
Propionyl-CoA carboxylase beta chain, mitochondrial PCCB Tbio Enzyme -1.77648 58.9 136