Development Level

Tbio 19 | 11,445
Tclin 5 | 613
Tchem 2 | 1,598

IMPC Phenotype

embryonic lethality prior to o... 4 | 239
preweaning lethality, complete... 4 | 979
abnormal embryo size 2 | 220
embryonic lethality prior to t... 2 | 278
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal ear morphology 1 | 9
abnormal embryonic autopod pla... 1 | 2
abnormal facial morphology 1 | 17
abnormal placenta morphology 1 | 5
abnormal retinal vasculature m... 1 | 27
decreased caudal vertebrae num... 1 | 53
decreased lean body mass 1 | 135
decreased prepulse inhibition 1 | 82
embryonic growth retardation 1 | 106
impaired glucose tolerance 1 | 75
increased bone mineral content 1 | 108
microphthalmia 1 | 26
prenatal lethality 1 | 28
preweaning lethality, incomple... 1 | 499
unresponsive to tactile stimul... 1 | 8

Disease

ovarian cancer 16 | 8,520
Carcinoma 15 | 11,493
medulloblastoma, large-cell 15 | 6,241
ependymoma 12 | 4,679
group 3 medulloblastoma 12 | 4,104
lung cancer 12 | 4,740
atypical teratoid / rhabdoid tumor 11 | 5,112
glioblastoma 11 | 5,792
oligodendroglioma 10 | 2,850
osteosarcoma 9 | 7,950
psoriasis 9 | 6,694
Breast cancer 8 | 3,578
lung adenocarcinoma 8 | 2,716
Cancer 7 | 2,499
non-small cell lung cancer 7 | 2,890
pancreatic cancer 7 | 2,398
primitive neuroectodermal tumor 7 | 3,035
tuberculosis 7 | 2,010
Astrocytoma, Pilocytic 6 | 3,081
Pick disease 6 | 1,894
astrocytic glioma 6 | 2,597
astrocytoma 6 | 1,146
interstitial cystitis 6 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
primary pancreatic ductal adenocarcinoma 6 | 1,109
subependymal giant cell astrocytoma 6 | 2,287
Autosomal recessive predisposition 5 | 1,442
adult high grade glioma 5 | 3,801
colon cancer 5 | 1,478
invasive ductal carcinoma 5 | 2,951
malignant mesothelioma 5 | 3,232
nasopharyngeal carcinoma 5 | 1,058
pediatric high grade glioma 5 | 1,064
Adenocarcinoma of lung 4 | 142
Disease Models, Animal 4 | 155
acute quadriplegic myopathy 4 | 1,158
diabetes mellitus 4 | 1,728
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Acute lymphoid leukemia 3 | 25
Atopic dermatitis 3 | 952
Carcinoma, Hepatocellular 3 | 228
Epilepsy 3 | 792
Failure to gain weight 3 | 365
Kidney cancer 3 | 2,613
Liver carcinoma 3 | 240
Multiple myeloma 3 | 1,332
Muscle hypotonia 3 | 571
Pediatric failure to thrive 3 | 365
Reticular dysgenesis 3 | 7
Rheumatoid arthritis 3 | 1,191
Seizures 3 | 596
adrenocortical carcinoma 3 | 1,428
ductal carcinoma in situ 3 | 1,745
hepatocellular carcinoma 3 | 547
ulcerative colitis 3 | 1,819
Anemia 2 | 365
Anteverted nostril 2 | 191
Arthritis, Rheumatoid 2 | 174
Atrial Fibrillation 2 | 124
Brachycephaly 2 | 88
Broad cranium shape 2 | 88
Colorectal Neoplasms 2 | 243
Congenital deafness 2 | 185
Deafness 2 | 198
Diarrhea 2 | 253
Dull intelligence 2 | 645
Endometriosis 2 | 540
Fever 2 | 138
Gait Ataxia 2 | 51
Gaucher disease type 1 2 | 180
Hearing Loss, Partial 2 | 185
Hemoglobin low 2 | 124
Herpes simplex 2 | 18
Malignant tumor of head and/or neck 2 | 15
Malignant tumor of ovary 2 | 25
Metastatic Breast Carcinoma 2 | 21
Myocardial Ischemia 2 | 169
Myoclonus 2 | 74
Neurogenic Muscular Atrophy 2 | 139
Neurogenic muscle atrophy, especially in the lower limbs 2 | 139
Purine nucleoside phosphorylase deficiency 2 | 11
Skeletal muscle atrophy 2 | 139
Thin upper lip vermilion 2 | 67
Waldenstrons macroglobulinemia 2 | 765
Weight decreased 2 | 103
Wide skull shape 2 | 88
active Crohn's disease 2 | 922
breast carcinoma 2 | 1,638
chronic rhinosinusitis 2 | 512
cutaneous lupus erythematosus 2 | 1,057
cystic fibrosis 2 | 1,696
gastric cancer 2 | 459
hearing impairment 2 | 199
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
lung carcinoma 2 | 2,843
muscle degeneration 2 | 139
non-small cell lung carcinoma 2 | 317
pituitary cancer 2 | 1,972
relapsing-remitting multiple sclerosis 2 | 18

Tissue

Blood and immune system 26 | 16,909
Cardiovascular System 26 | 15,192
Digestive Tract 26 | 17,369
Endocrine System 26 | 18,159
Female tissues 26 | 17,400
Liver and Pancreas 26 | 16,750
Male tissues 26 | 17,142
Nervous System 26 | 16,725
Respiratory system 26 | 16,393
Skin and soft tissues 26 | 17,230
Urinary Tract 26 | 16,678

Target Family

Kinase 13 | 634
Enzyme 10 | 4,145
Non-IDG 3 | 12,091

PathwayCommons: panther Pathway

http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 264 | 264
http://identifiers.org/panther... 197 | 197
http://identifiers.org/panther... 164 | 164
http://identifiers.org/panther... 151 | 151
http://identifiers.org/panther... 150 | 150
http://identifiers.org/panther... 149 | 149
http://identifiers.org/panther... 146 | 146
http://identifiers.org/panther... 124 | 124
http://identifiers.org/panther... 118 | 118
http://identifiers.org/panther... 116 | 116
http://identifiers.org/panther... 115 | 115
http://identifiers.org/panther... 110 | 110
http://identifiers.org/panther... 107 | 107
http://identifiers.org/panther... 104 | 104
http://identifiers.org/panther... 91 | 91
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 86 | 86
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 67 | 67
http://identifiers.org/panther... 65 | 65
http://identifiers.org/panther... 63 | 63
http://identifiers.org/panther... 61 | 61
http://identifiers.org/panther... 60 | 60
http://identifiers.org/panther... 56 | 56
http://identifiers.org/panther... 54 | 54
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 51 | 51
http://identifiers.org/panther... 47 | 47
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 44 | 44
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 41 | 41
http://identifiers.org/panther... 38 | 38
http://identifiers.org/panther... 37 | 37
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 33 | 33
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 31 | 31
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 27 | 27
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 17 | 17
http://identifiers.org/panther... 16 | 16
http://identifiers.org/panther... 15 | 15
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 13 | 13
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 8 | 8
http://identifiers.org/panther... 8 | 8

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nucleoside diphosphate kinase 7 NME7 Tbio Enzyme -0.83479 6.29 113
Adenylate kinase isoenzyme 5 AK5 Tbio Kinase -1.83209 76.0 225
Adenylate kinase 2, mitochondrial AK2 Tbio Kinase -2.00007 98.7 330
Adenylate kinase 4, mitochondrial AK4 Tbio Kinase -1.83029 66.5 272
GTP:AMP phosphotransferase AK3, mitochondrial AK3 Tbio Kinase -1.37969 23.5 249
Bifunctional purine biosynthesis protein PURH ATIC Tchem Non-IDG -2.93014 835.0 246
Nucleoside diphosphate kinase A NME1 Tbio Kinase -2.99077 863.1 945
Nucleoside diphosphate kinase, mitochondrial NME4 Tbio Kinase -1.75871 56.4 240
Nucleoside diphosphate kinase homolog 5 NME5 Tbio Kinase -0.86091 6.37 122
Adenylate kinase isoenzyme 1 AK1 Tbio Kinase -2.37718 230.1 422