Development Level

Tbio 22 | 11,445
Tchem 21 | 1,598
Tclin 2 | 613

IMPC Phenotype

preweaning lethality, complete... 4 | 979
preweaning lethality, incomple... 4 | 499
abnormal heart morphology 2 | 162
abnormal lens morphology 2 | 81
abnormal seminal vesicle morph... 2 | 114
cataract 2 | 92
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
increased circulating choleste... 2 | 66
abnormal bone mineralization 1 | 38
abnormal epididymis morphology 1 | 42
abnormal glucose homeostasis 1 | 4
abnormal heart left ventricle ... 1 | 16
abnormal lung morphology 1 | 26
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal spinal cord morpholog... 1 | 9
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
cardiovascular system phenotyp... 1 | 36
decreased body weight 1 | 161
decreased circulating LDL chol... 1 | 38
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating triglyce... 1 | 79
enlarged epididymis 1 | 31
enlarged heart atrium 1 | 4
enlarged spleen 1 | 41
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating sodium l... 1 | 71
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased total body fat amoun... 1 | 134
small seminal vesicle 1 | 10
small testis 1 | 58
thrombocytosis 1 | 27
urinary bladder obstruction 1 | 4

Disease

Cancer 39 | 2,499
ovarian cancer 34 | 8,520
Carcinoma 30 | 11,493
osteosarcoma 28 | 7,950
Breast cancer 25 | 3,578
lung cancer 25 | 4,740
medulloblastoma, large-cell 24 | 6,241
psoriasis 24 | 6,694
glioblastoma 23 | 5,792
atypical teratoid / rhabdoid tumor 20 | 5,112
adult high grade glioma 15 | 3,801
group 3 medulloblastoma 15 | 4,104
Breast Neoplasms 14 | 445
Kidney cancer 13 | 2,613
Mammary Neoplasms 13 | 425
Prostatic Neoplasms 13 | 495
ependymoma 13 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
lung adenocarcinoma 13 | 2,716
malignant mesothelioma 13 | 3,232
primitive neuroectodermal tumor 13 | 3,035
diabetes mellitus 12 | 1,728
non-small cell lung cancer 12 | 2,890
Epilepsy 11 | 792
Seizures 11 | 596
Melanoma 10 | 711
Schizophrenia 10 | 1,160
Squamous cell carcinoma 10 | 129
adrenocortical carcinoma 10 | 1,428
pancreatic cancer 10 | 2,398
subependymal giant cell astrocytoma 10 | 2,287
Carcinoma, Squamous Cell 9 | 110
Dull intelligence 9 | 645
Endometriosis 9 | 540
Hypoplastic mandible condyle 9 | 275
Intellectual disability 9 | 1,016
Low intelligence 9 | 645
Mandibular hypoplasia 9 | 275
Mental Retardation 9 | 645
Mental deficiency 9 | 645
Micrognathism 9 | 275
Poor school performance 9 | 645
Short stature 9 | 531
Stomach Neoplasms 9 | 300
breast carcinoma 9 | 1,638
Acquired scoliosis 8 | 281
Astrocytoma, Pilocytic 8 | 3,081
Autosomal recessive predisposition 8 | 1,442
Byzanthine arch palate 8 | 194
Congenital deafness 8 | 185
Curvature of spine 8 | 282
Deafness 8 | 198
Downward slant of palpebral fissure 8 | 158
Endometrial cancer 8 | 311
Hearing Loss, Partial 8 | 185
Lung Neoplasms 8 | 232
Microstomia 8 | 78
Skin cancer 8 | 469
acute quadriplegic myopathy 8 | 1,158
colon cancer 8 | 1,478
ductal carcinoma in situ 8 | 1,745
hearing impairment 8 | 199
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
juvenile dermatomyositis 8 | 1,187
oligodendroglioma 8 | 2,850
Cataract 7 | 297
Decreased projection of maxilla 7 | 66
Deficiency of upper jaw bones 7 | 66
Hypoplasia of the maxilla 7 | 66
Hypotrophic maxilla 7 | 66
Lymphoid leukemia 7 | 160
Maxillary retrognathia 7 | 66
Pancreatic Neoplasm 7 | 85
Retrusion of upper jaw bones 7 | 66
Strabismus 7 | 270
astrocytic glioma 7 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
invasive ductal carcinoma 7 | 2,951
nasopharyngeal carcinoma 7 | 1,058
ulcerative colitis 7 | 1,819
Adenoid Cystic Carcinoma 6 | 99
Adenoma 6 | 167
Bladder Neoplasm 6 | 112
Carcinoma, Adenoid Cystic 6 | 99
Carcinoma, Hepatocellular 6 | 228
Cognitive delay 6 | 608
Glaucoma 6 | 239
Global developmental delay 6 | 608
Immune system cancer 6 | 140
Lens Opacities 6 | 231
Liver cancer 6 | 604
Liver carcinoma 6 | 240
Mental and motor retardation 6 | 608
Multiple myeloma 6 | 1,332
Pectus excavatum 6 | 100
Urinary Bladder Neoplasms 6 | 114
Vascular disease 6 | 319
Ventricular Septal Defects 6 | 119
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
tuberculosis 6 | 2,010

Tissue

Endocrine System 44 | 18,159
Female tissues 44 | 17,400
Blood and immune system 43 | 16,909
Digestive Tract 43 | 17,369
Liver and Pancreas 43 | 16,750
Male tissues 43 | 17,142
Nervous System 43 | 16,725
Respiratory system 43 | 16,393
Skin and soft tissues 43 | 17,230
Urinary Tract 43 | 16,678
Cardiovascular System 42 | 15,192

Target Family

Non-IDG 13 | 12,091
Enzyme 11 | 4,145
Kinase 10 | 634
Epigenetic 6 | 242
Transcription Factor 5 | 1,400

PathwayCommons: panther Pathway

http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 264 | 264
http://identifiers.org/panther... 197 | 197
http://identifiers.org/panther... 164 | 164
http://identifiers.org/panther... 151 | 151
http://identifiers.org/panther... 150 | 150
http://identifiers.org/panther... 149 | 149
http://identifiers.org/panther... 146 | 146
http://identifiers.org/panther... 124 | 124
http://identifiers.org/panther... 118 | 118
http://identifiers.org/panther... 116 | 116
http://identifiers.org/panther... 115 | 115
http://identifiers.org/panther... 110 | 110
http://identifiers.org/panther... 107 | 107
http://identifiers.org/panther... 104 | 104
http://identifiers.org/panther... 91 | 91
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 86 | 86
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 67 | 67
http://identifiers.org/panther... 65 | 65
http://identifiers.org/panther... 63 | 63
http://identifiers.org/panther... 61 | 61
http://identifiers.org/panther... 60 | 60
http://identifiers.org/panther... 56 | 56
http://identifiers.org/panther... 54 | 54
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 51 | 51
http://identifiers.org/panther... 47 | 47
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 44 | 44
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 41 | 41
http://identifiers.org/panther... 38 | 38
http://identifiers.org/panther... 37 | 37
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 33 | 33
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 31 | 31
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 27 | 27
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 17 | 17
http://identifiers.org/panther... 16 | 16
http://identifiers.org/panther... 15 | 15
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 13 | 13
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 8 | 8
http://identifiers.org/panther... 8 | 8

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine/threonine-protein kinase ATR ATR Tchem Kinase -2.80362 549.6 376
Metastasis-associated protein MTA2 MTA2 Tbio Transcription Factor -1.59201 32.3 283
Tumor protein p73 TP73 Tbio Transcription Factor -1.92832 82.6 708
Serine/threonine-protein kinase Chk2 CHEK2 Tchem Kinase -3.00304 978.7 1374
Putative tyrosine-protein phosphatase TPTE TPTE Tbio Enzyme -2.11875 127.6 234
Cyclin-dependent kinase inhibitor 2A CDKN2A Tbio Enzyme -3.72848 9058.6 1063