Development Level

Tbio 166 | 11,445
Tdark 57 | 6,588
Tchem 35 | 1,598
Tclin 6 | 613

Collection

RFA-RM-18-021 5 | 328
Kinase: IDG Consortium (Target... 4 | 125
Kinase: IDG Consortium (Comple... 2 | 37
GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, complete... 17 | 979
preweaning lethality, incomple... 10 | 499
decreased total body fat amoun... 6 | 207
decreased vertical activity 6 | 208
embryonic lethality prior to t... 6 | 278
increased lean body mass 6 | 172
abnormal behavior 5 | 298
decreased body weight 5 | 161
small superior vagus ganglion 5 | 74
abnormal bone structure 4 | 187
abnormal heart morphology 4 | 162
decreased prepulse inhibition 4 | 82
enlarged heart 4 | 210
increased startle reflex 4 | 112
short tibia 4 | 97
abnormal embryo size 3 | 220
abnormal lens morphology 3 | 81
decreased bone mineral content 3 | 151
decreased bone mineral density 3 | 126
decreased startle reflex 3 | 75
edema 3 | 59
embryonic lethality prior to o... 3 | 239
hydrometra 3 | 53
hypoactivity 3 | 132
increased bone mineral content 3 | 108
increased circulating HDL chol... 3 | 80
increased circulating alkaline... 3 | 122
increased circulating choleste... 3 | 66
increased mean corpuscular vol... 3 | 92
increased or absent threshold ... 3 | 101
increased total body fat amoun... 3 | 134
male infertility 3 | 123
mammalian phenotype 3 | 17
abnormal bone mineralization 2 | 38
abnormal eye morphology 2 | 68
abnormal gait 2 | 69
abnormal head morphology 2 | 10
abnormal kidney morphology 2 | 65
abnormal locomotor behavior 2 | 24
abnormal neural tube closure 2 | 46
abnormal seminal vesicle morph... 2 | 114
abnormal startle reflex 2 | 15
abnormal vocalization 2 | 21
cardiovascular system phenotyp... 2 | 36
corneal opacity 2 | 32
decreased circulating calcium ... 2 | 36
decreased circulating insulin ... 2 | 76
decreased circulating total pr... 2 | 49
decreased circulating triglyce... 2 | 79
decreased grip strength 2 | 116
decreased heart left ventricle... 2 | 28
decreased lean body mass 2 | 135
decreased lymphocyte cell numb... 2 | 83
impaired glucose tolerance 2 | 75
increased hematocrit 2 | 46
increased hemoglobin content 2 | 45
increased mean corpuscular hem... 2 | 96
increased vertical activity 2 | 24
microphthalmia 2 | 26
small testis 2 | 58
thrombocytopenia 2 | 56
abnormal behavioral response t... 1 | 66
abnormal coat- hair morphology 1 | 19
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal retinal vasculature m... 1 | 27
abnormal tail movements 1 | 12
abnormal testis morphology 1 | 43
decreased IgG1 level 1 | 8
decreased body length 1 | 101
decreased circulating amylase ... 1 | 28
decreased circulating creatini... 1 | 39
decreased circulating iron lev... 1 | 32
decreased circulating magnesiu... 1 | 13
decreased circulating serum al... 1 | 82
decreased erythrocyte cell num... 1 | 62
decreased fluid intake 1 | 3
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 31
decreased total retina thickne... 1 | 17
enlarged spleen 1 | 41
impaired pupillary reflex 1 | 26
increased body length 1 | 32
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating calcium ... 1 | 34
increased circulating creatini... 1 | 38
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
increased fasted circulating g... 1 | 76
increased monocyte cell number 1 | 63
increased prepulse inhibition 1 | 32
prenatal lethality 1 | 28
shortened RR interval 1 | 17
small kidney 1 | 16
thrombocytosis 1 | 27
vertebral fusion 1 | 23

Disease

Carcinoma 218 | 11,493
psoriasis 128 | 6,694
ovarian cancer 126 | 8,520
osteosarcoma 116 | 7,950
Kidney cancer 107 | 2,613
glioblastoma 103 | 5,792
medulloblastoma, large-cell 103 | 6,241
atypical teratoid / rhabdoid tumor 100 | 5,112
ependymoma 94 | 4,679
lung cancer 87 | 4,740
Breast cancer 81 | 3,578
group 3 medulloblastoma 72 | 4,104
Cancer 71 | 2,499
lung carcinoma 65 | 2,843
primitive neuroectodermal tumor 64 | 3,035
oligodendroglioma 61 | 2,850
adult high grade glioma 60 | 3,801
Astrocytoma, Pilocytic 58 | 3,081
malignant mesothelioma 57 | 3,232
astrocytic glioma 53 | 2,597
invasive ductal carcinoma 48 | 2,951
lung adenocarcinoma 46 | 2,716
non-small cell lung cancer 46 | 2,890
subependymal giant cell astrocytoma 46 | 2,287
group 4 medulloblastoma 44 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 44 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 43 | 3,291
pancreatic cancer 42 | 2,398
interstitial cystitis 41 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 37 | 2,955
Pick disease 36 | 1,894
Liver cancer 33 | 604
Schizophrenia 31 | 1,160
pituitary cancer 31 | 1,972
ductal carcinoma in situ 29 | 1,745
Rheumatoid arthritis 28 | 1,191
breast carcinoma 28 | 1,638
Intellectual disability 27 | 1,016
cystic fibrosis 27 | 1,696
astrocytoma 26 | 1,146
Melanoma 25 | 711
ulcerative colitis 25 | 1,819
Skin cancer 24 | 469
colon cancer 24 | 1,478
pediatric high grade glioma 24 | 1,064
Bipolar Disorder 23 | 666
tuberculosis 23 | 2,010
Endometrial cancer 21 | 311
Colorectal Neoplasms 19 | 243
Multiple myeloma 19 | 1,332
Autosomal recessive predisposition 18 | 1,442
Dull intelligence 18 | 645
Low intelligence 18 | 645
Mental Retardation 18 | 645
Mental deficiency 18 | 645
Obesity 18 | 678
Poor school performance 18 | 645
active Crohn's disease 18 | 922
primary pancreatic ductal adenocarcinoma 18 | 1,109
Short stature 17 | 531
adrenocortical carcinoma 17 | 1,428
Prostatic Neoplasms 16 | 495
juvenile dermatomyositis 16 | 1,187
medulloblastoma 16 | 720
Alcoholic Intoxication, Chronic 15 | 289
acute myeloid leukemia 15 | 783
non primary Sjogren syndrome sicca 15 | 891
Autistic Disorder 14 | 364
Cognitive delay 14 | 608
Epilepsy 14 | 792
Global developmental delay 14 | 608
Mental and motor retardation 14 | 608
Osteoporosis 14 | 363
Waldenstrons macroglobulinemia 14 | 765
acute quadriplegic myopathy 14 | 1,158
autosomal dominant Emery-Dreifuss muscular dystrophy 14 | 510
cutaneous lupus erythematosus 14 | 1,057
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,962
spina bifida 14 | 1,074
Broad flat nasal bridge 13 | 236
Duchenne muscular dystrophy 13 | 601
Hypoplastic mandible condyle 13 | 275
Mandibular hypoplasia 13 | 275
Micrognathism 13 | 275
Nasal bridge wide 13 | 236
Seizures 13 | 596
esophageal adenocarcinoma 13 | 737
Acquired scoliosis 12 | 281
Breast Neoplasms 12 | 445
Cryptorchidism 12 | 296
Curvature of spine 12 | 282
active ulcerative colitis 12 | 764
diabetes mellitus 12 | 1,728
gastric carcinoma 12 | 807
Depressive disorder 11 | 409
Liver Cirrhosis, Experimental 11 | 769
Mental Depression 11 | 333
Small head 11 | 374
Strabismus 11 | 270
aldosterone-producing adenoma 11 | 665

Tissue

Endocrine System 261 | 18,159
Female tissues 258 | 17,400
Nervous System 258 | 16,725
Male tissues 257 | 17,142
Digestive Tract 255 | 17,369
Skin and soft tissues 251 | 17,230
Liver and Pancreas 247 | 16,750
Urinary Tract 245 | 16,678
Blood and immune system 244 | 16,909
Respiratory system 242 | 16,393
Cardiovascular System 218 | 15,192

Target Family

Non-IDG 177 | 12,091
Kinase 26 | 634
Enzyme 21 | 4,145
GPCR 13 | 408
Transcription Factor 12 | 1,400
Epigenetic 10 | 242
Ion Channel 3 | 344
TF/Epigenetic 2 | 38

PathwayCommons: panther Pathway

http://identifiers.org/panther... 264 | 264
http://identifiers.org/panther... 197 | 197
http://identifiers.org/panther... 164 | 164
http://identifiers.org/panther... 151 | 151
http://identifiers.org/panther... 150 | 150
http://identifiers.org/panther... 149 | 149
http://identifiers.org/panther... 146 | 146
http://identifiers.org/panther... 124 | 124
http://identifiers.org/panther... 118 | 118
http://identifiers.org/panther... 116 | 116
http://identifiers.org/panther... 115 | 115
http://identifiers.org/panther... 110 | 110
http://identifiers.org/panther... 107 | 107
http://identifiers.org/panther... 104 | 104
http://identifiers.org/panther... 91 | 91
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 86 | 86
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 67 | 67
http://identifiers.org/panther... 65 | 65
http://identifiers.org/panther... 63 | 63
http://identifiers.org/panther... 61 | 61
http://identifiers.org/panther... 60 | 60
http://identifiers.org/panther... 56 | 56
http://identifiers.org/panther... 54 | 54
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 51 | 51
http://identifiers.org/panther... 47 | 47
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 44 | 44
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 41 | 41
http://identifiers.org/panther... 38 | 38
http://identifiers.org/panther... 37 | 37
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 33 | 33
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 31 | 31
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 27 | 27
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 17 | 17
http://identifiers.org/panther... 16 | 16
http://identifiers.org/panther... 15 | 15
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 13 | 13
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 8 | 8
http://identifiers.org/panther... 8 | 8

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Probable global transcription activator SNF2L1 SMARCA1 Tbio Non-IDG -2.20560 145.6 116
Cadherin-18 CDH18 Tdark Non-IDG -0.64897 4.11 125
Protocadherin beta-14 PCDHB14 Tdark Non-IDG 0.78 0.14 90
Protocadherin beta-12 PCDHB12 Tdark Non-IDG 0.00000 88
Protocadherin beta-13 PCDHB13 Tdark Non-IDG 0.00000 101
Protocadherin gamma-C4 PCDHGC4 Tdark Non-IDG 0.60 0.18 87
Protocadherin gamma-B6 PCDHGB6 Tdark Non-IDG -0.35576 1.87 8
Protocadherin gamma-B7 PCDHGB7 Tdark Non-IDG -1.62113 42.6 4
Protocadherin beta-6 PCDHB6 Tdark Non-IDG 1.04 0.08 32
Protocadherin alpha-13 PCDHA13 Tdark Non-IDG 0.37 0.38 6