Development Level

Tbio 9 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal digit morphology 1 | 10
decreased IgM level 1 | 1
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased total body fat amoun... 1 | 207
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased bone mineral content 1 | 108
increased circulating amylase ... 1 | 25
increased circulating choleste... 1 | 66
increased lean body mass 1 | 172

Disease

Carcinoma 8 | 11,493
glioblastoma 6 | 5,792
osteosarcoma 6 | 7,950
ovarian cancer 6 | 8,520
Cognitive delay 5 | 608
Global developmental delay 5 | 608
Mental and motor retardation 5 | 608
Muscle hypotonia 5 | 571
medulloblastoma, large-cell 5 | 6,241
psoriasis 5 | 6,694
Autosomal recessive predisposition 4 | 1,442
Cerebellar Ataxia 4 | 304
Cerebral atrophy 4 | 178
Multiple myeloma 4 | 1,332
astrocytic glioma 4 | 2,597
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Acidosis, Lactic 3 | 97
Degenerative brain disorder 3 | 100
Epilepsy 3 | 792
Failure to gain weight 3 | 365
Infantile onset 3 | 238
Pediatric failure to thrive 3 | 365
Pick disease 3 | 1,894
Seizures 3 | 596
Stomach Neoplasms 3 | 300
Supratentorial atrophy 3 | 94
adult high grade glioma 3 | 3,801
atypical teratoid / rhabdoid tumor 3 | 5,112
ependymoma 3 | 4,679
ulcerative colitis 3 | 1,819
Agenesis of corpus callosum 2 | 83
Anteverted nostril 2 | 191
Astrocytoma, Pilocytic 2 | 3,081
Cancer 2 | 2,499
Cardiomyopathies 2 | 110
Disease Progression 2 | 136
Dull intelligence 2 | 645
Frontal bossing 2 | 157
Highly variable clinical phenotype 2 | 150
Highly variable phenotype and severity 2 | 150
Highly variable phenotype, even within families 2 | 150
Hyperhidrosis disorder 2 | 81
Increased serum lactate 2 | 60
Increased sweating 2 | 81
Intellectual disability 2 | 1,016
Kidney cancer 2 | 2,613
Lactic acidemia 2 | 95
Lactic acidosis 2 | 51
Leigh disease 2 | 100
Low Vision 2 | 174
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Metabolic acidosis 2 | 90
Neurogenic Muscular Atrophy 2 | 139
Neurogenic muscle atrophy, especially in the lower limbs 2 | 139
Optic Atrophy 2 | 242
Phenotypic variability 2 | 150
Poor school performance 2 | 645
Respiratory Distress Syndrome, Adult 2 | 40
Respiratory Failure 2 | 104
Severe mental retardation (I.Q. 20-34) 2 | 99
Sideroblastic anemia with spinocerebellar ataxia 2 | 6
Skeletal muscle atrophy 2 | 139
Small head 2 | 374
Sweating 2 | 81
Visual Impairment 2 | 174
Von Hippel-Lindau disease 2 | 19
acute quadriplegic myopathy 2 | 1,158
aldosterone-producing adenoma 2 | 665
ductal carcinoma in situ 2 | 1,745
group 3 medulloblastoma 2 | 4,104
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
muscle degeneration 2 | 139
oligodendroglioma 2 | 2,850
primitive neuroectodermal tumor 2 | 3,035
Choroid plexus cyst 1 | 2
Coffin-Lowry syndrome 1 | 9
Death in childhood 1 | 14
Elevated heart rate 1 | 25
Episodic ataxia 1 | 22
Gait, Unsteady 1 | 29
Gastrointestinal stromal tumor 1 | 62
Goiter 1 | 38
Increased gastric cancer 1 | 21
Leiomyoma 1 | 32
Methylmalonic aciduria 1 | 9
Neurofibromatosis 1 | 40
Palpitations 1 | 18
Paraganglioma 1 | 15
Persistent generalized lymphadenopathy 1 | 15
Phaeochromocytoma 1 | 20
Pheochromocytoma 1 | 24
Reduced visual acuity 1 | 63
Relative macrocephaly 1 | 12
Retinitis pigmentosa 28 1 | 19
Skin Abnormalities 1 | 37
Uterine fibroid 1 | 28

Tissue

Endocrine System 10 | 18,159
Blood and immune system 9 | 16,909
Cardiovascular System 9 | 15,192
Digestive Tract 9 | 17,369
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678

Target Family

Enzyme 9 | 4,145
Kinase 1 | 634

PathwayCommons: panther Pathway

http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 264 | 264
http://identifiers.org/panther... 197 | 197
http://identifiers.org/panther... 164 | 164
http://identifiers.org/panther... 151 | 151
http://identifiers.org/panther... 150 | 150
http://identifiers.org/panther... 149 | 149
http://identifiers.org/panther... 146 | 146
http://identifiers.org/panther... 124 | 124
http://identifiers.org/panther... 118 | 118
http://identifiers.org/panther... 116 | 116
http://identifiers.org/panther... 115 | 115
http://identifiers.org/panther... 110 | 110
http://identifiers.org/panther... 107 | 107
http://identifiers.org/panther... 104 | 104
http://identifiers.org/panther... 91 | 91
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 86 | 86
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 67 | 67
http://identifiers.org/panther... 65 | 65
http://identifiers.org/panther... 63 | 63
http://identifiers.org/panther... 61 | 61
http://identifiers.org/panther... 60 | 60
http://identifiers.org/panther... 56 | 56
http://identifiers.org/panther... 54 | 54
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 51 | 51
http://identifiers.org/panther... 47 | 47
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 44 | 44
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http://identifiers.org/panther... 38 | 38
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http://identifiers.org/panther... 32 | 32
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http://identifiers.org/panther... 18 | 18
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http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 8 | 8
http://identifiers.org/panther... 8 | 8

This is where graphics are reside..