Development Level

Tbio 39 | 11,445
Tchem 33 | 1,598
Tclin 11 | 613
Tdark 5 | 6,588

Collection

Kinase: IDG Consortium (Target... 4 | 125
Kinase: IDG Consortium (Comple... 2 | 37
GPCR: IDG Consortium (Complete... 1 | 25
GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, complete... 4 | 979
preweaning lethality, incomple... 4 | 499
decreased bone mineral content 2 | 151
decreased large unstained cell... 2 | 11
increased blood urea nitrogen ... 2 | 48
short tibia 2 | 97
thrombocytopenia 2 | 56
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal coat appearance 1 | 31
abnormal cranium morphology 1 | 36
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal maxilla morphology 1 | 17
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal spine curvature 1 | 9
abnormal testis morphology 1 | 43
abnormal thymus morphology 1 | 7
cardiovascular system phenotyp... 1 | 36
decreased body length 1 | 101
decreased circulating HDL chol... 1 | 68
decreased circulating insulin ... 1 | 76
decreased circulating lactate ... 1 | 3
decreased circulating serum al... 1 | 82
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased total body fat amoun... 1 | 207
decreased total retina thickne... 1 | 17
decreased vertical activity 1 | 208
edema 1 | 59
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
hyperactivity 1 | 148
impaired pupillary reflex 1 | 26
improved glucose tolerance 1 | 79
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 39
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
increased total body fat amoun... 1 | 134
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
small spleen 1 | 19
small testis 1 | 58
small thymus 1 | 16
thrombocytosis 1 | 27

Disease

Carcinoma 58 | 11,493
ovarian cancer 53 | 8,520
osteosarcoma 45 | 7,950
glioblastoma 40 | 5,792
medulloblastoma, large-cell 37 | 6,241
psoriasis 37 | 6,694
Cancer 34 | 2,499
atypical teratoid / rhabdoid tumor 33 | 5,112
lung cancer 30 | 4,740
ependymoma 26 | 4,679
oligodendroglioma 26 | 2,850
group 3 medulloblastoma 25 | 4,104
Astrocytoma, Pilocytic 22 | 3,081
Breast cancer 22 | 3,578
adult high grade glioma 22 | 3,801
diabetes mellitus 19 | 1,728
interstitial cystitis 19 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,989
Multiple myeloma 18 | 1,332
astrocytic glioma 18 | 2,597
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,291
primitive neuroectodermal tumor 18 | 3,035
Parkinson's disease 17 | 392
Schizophrenia 17 | 1,160
lung adenocarcinoma 17 | 2,716
invasive ductal carcinoma 16 | 2,951
Alzheimer's disease 15 | 658
Waldenstrons macroglobulinemia 15 | 765
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
malignant mesothelioma 15 | 3,232
Bipolar Disorder 14 | 666
Pick disease 14 | 1,894
non-small cell lung cancer 14 | 2,890
subependymal giant cell astrocytoma 14 | 2,287
dermatomyositis 13 | 966
group 4 medulloblastoma 13 | 1,855
pancreatic cancer 13 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,962
tuberculosis 13 | 2,010
Blastic phase chronic myeloid leukemia 11 | 58
Chronic Myelocytic Leukemia Accelerated Phase 11 | 59
astrocytoma 10 | 1,146
juvenile dermatomyositis 10 | 1,187
Chronic phase chronic myeloid leukemia 9 | 45
Philadelphia Chromosome Positive Chronic Myelocytic Leukemia 9 | 45
Philadelphia chromosome-positive acute lymphoblastic leukemia 9 | 47
Rheumatoid arthritis 9 | 1,191
Vascular disease 9 | 319
ductal carcinoma in situ 9 | 1,745
Depressive disorder 8 | 409
colon cancer 8 | 1,478
cutaneous lupus erythematosus 8 | 1,057
cystic fibrosis 8 | 1,696
pituitary cancer 8 | 1,972
Dementia 7 | 175
Down syndrome 7 | 499
Kidney cancer 7 | 2,613
Major Depressive Disorder 7 | 301
Multiple system atrophy 7 | 29
Nerve Degeneration 7 | 121
Neurodegenerative disease 7 | 414
Toxic encephalopathy 7 | 141
breast carcinoma 7 | 1,638
lung carcinoma 7 | 2,843
progressive supranuclear palsy 7 | 676
Amyotrophic lateral sclerosis 6 | 451
Autosomal recessive predisposition 6 | 1,442
Breast Neoplasms 6 | 445
Carcinoma, Hepatocellular 6 | 228
Carcinoma, Squamous Cell 6 | 110
Cardiomyopathies 6 | 110
Dystonia 6 | 164
HIV Infections 6 | 102
Hyperalgesia 6 | 83
Intellectual disability 6 | 1,016
Liver Cirrhosis, Experimental 6 | 769
Liver carcinoma 6 | 240
Mammary Neoplasms 6 | 425
Mental Depression 6 | 333
Obesity 6 | 678
Parkinsonian Disorders 6 | 56
Renal Cell Carcinoma 6 | 214
Squamous cell carcinoma 6 | 129
Stomach Neoplasms 6 | 300
Unipolar Depression 6 | 250
active Crohn's disease 6 | 922
acute quadriplegic myopathy 6 | 1,158
adrenocortical carcinoma 6 | 1,428
esophageal adenocarcinoma 6 | 737
non primary Sjogren syndrome sicca 6 | 891
pediatric high grade glioma 6 | 1,064
primary Sjogren syndrome 6 | 735
ulcerative colitis 6 | 1,819
Arthritis 5 | 290
Chronic Lymphocytic Leukemia 5 | 262
Cognitive delay 5 | 608
Global developmental delay 5 | 608
Kidney disease 5 | 430
Mental and motor retardation 5 | 608
primary pancreatic ductal adenocarcinoma 5 | 1,109

Tissue

Endocrine System 88 | 18,159
Digestive Tract 87 | 17,369
Female tissues 87 | 17,400
Blood and immune system 86 | 16,909
Nervous System 86 | 16,725
Male tissues 85 | 17,142
Skin and soft tissues 85 | 17,230
Urinary Tract 85 | 16,678
Liver and Pancreas 83 | 16,750
Respiratory system 83 | 16,393
Cardiovascular System 81 | 15,192

Target Family

Non-IDG 35 | 12,091
Kinase 31 | 634
Enzyme 17 | 4,145
GPCR 2 | 408
Transcription Factor 2 | 1,400
Transporter 1 | 473

PathwayCommons: panther Pathway

http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 264 | 264
http://identifiers.org/panther... 197 | 197
http://identifiers.org/panther... 164 | 164
http://identifiers.org/panther... 151 | 151
http://identifiers.org/panther... 150 | 150
http://identifiers.org/panther... 149 | 149
http://identifiers.org/panther... 146 | 146
http://identifiers.org/panther... 124 | 124
http://identifiers.org/panther... 118 | 118
http://identifiers.org/panther... 116 | 116
http://identifiers.org/panther... 115 | 115
http://identifiers.org/panther... 110 | 110
http://identifiers.org/panther... 107 | 107
http://identifiers.org/panther... 104 | 104
http://identifiers.org/panther... 91 | 91
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 86 | 86
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 67 | 67
http://identifiers.org/panther... 65 | 65
http://identifiers.org/panther... 63 | 63
http://identifiers.org/panther... 61 | 61
http://identifiers.org/panther... 60 | 60
http://identifiers.org/panther... 56 | 56
http://identifiers.org/panther... 54 | 54
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 51 | 51
http://identifiers.org/panther... 47 | 47
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 44 | 44
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 41 | 41
http://identifiers.org/panther... 38 | 38
http://identifiers.org/panther... 37 | 37
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 33 | 33
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 31 | 31
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 27 | 27
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 17 | 17
http://identifiers.org/panther... 16 | 16
http://identifiers.org/panther... 15 | 15
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 13 | 13
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 8 | 8
http://identifiers.org/panther... 8 | 8

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proteasome subunit beta type-10 PSMB10 Tchem Enzyme -1.88722 74.3 178
14-3-3 protein theta YWHAQ Tchem Non-IDG -2.43493 235.4 358
Heat shock-related 70 kDa protein 2 HSPA2 Tbio Non-IDG -1.98655 104.3 162
Tyrosine-protein kinase FRK FRK Tchem Kinase -1.68365 49.2 394
Septin-5 SEPT5 Tbio Non-IDG -1.71017 49.4 178
Gamma-synuclein SNCG Tbio Non-IDG -2.24895 187.3 294
Heat shock 70 kDa protein 1A HSPA1B Tchem Non-IDG -3.10995 0.00000 1174
Heat shock 70 kDa protein 1B HSPA1B Tbio Non-IDG -1.61862 0.00000 60
Tyrosine-protein kinase Blk BLK Tchem Kinase -1.88753 81.6 418
Sodium-dependent dopamine transporter SLC6A3 Tclin Transporter -3.59848 3752.4 324