Development Level

Tbio 22 | 11,445
Tchem 19 | 1,598
Tdark 3 | 6,588
Tclin 1 | 613

Collection

Kinase: IDG Consortium (Target... 2 | 125
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

decreased lean body mass 2 | 135
abnormal coat appearance 1 | 31
abnormal coat-hair pigmentatio... 1 | 64
abnormal gait 1 | 69
abnormal humerus morphology 1 | 11
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased circulating magnesiu... 1 | 13
decreased circulating potassiu... 1 | 20
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
enlarged lymph nodes 1 | 37
female infertility 1 | 60
impaired righting response 1 | 26
increased circulating sodium l... 1 | 71
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
increased neutrophil cell numb... 1 | 46
male infertility 1 | 123

Disease

Carcinoma 30 | 11,493
ovarian cancer 26 | 8,520
glioblastoma 24 | 5,792
psoriasis 23 | 6,694
osteosarcoma 22 | 7,950
Cancer 19 | 2,499
atypical teratoid / rhabdoid tumor 19 | 5,112
lung cancer 19 | 4,740
medulloblastoma, large-cell 17 | 6,241
ependymoma 16 | 4,679
group 4 medulloblastoma 15 | 1,855
malignant mesothelioma 15 | 3,232
Breast cancer 13 | 3,578
adult high grade glioma 13 | 3,801
Astrocytoma, Pilocytic 11 | 3,081
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
pancreatic cancer 11 | 2,398
pituitary cancer 11 | 1,972
primitive neuroectodermal tumor 11 | 3,035
Vascular disease 10 | 319
group 3 medulloblastoma 10 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
invasive ductal carcinoma 10 | 2,951
tuberculosis 10 | 2,010
colon cancer 9 | 1,478
diabetes mellitus 9 | 1,728
non-small cell lung cancer 9 | 2,890
subependymal giant cell astrocytoma 9 | 2,287
ulcerative colitis 9 | 1,819
Multiple myeloma 8 | 1,332
astrocytic glioma 8 | 2,597
astrocytoma 8 | 1,146
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
oligodendroglioma 8 | 2,850
Alzheimer's disease 7 | 658
acute quadriplegic myopathy 7 | 1,158
interstitial cystitis 7 | 2,312
lung carcinoma 7 | 2,843
Parkinson's disease 6 | 392
Schizophrenia 6 | 1,160
Waldenstrons macroglobulinemia 6 | 765
acute myeloid leukemia 6 | 783
breast carcinoma 6 | 1,638
dermatomyositis 6 | 966
ductal carcinoma in situ 6 | 1,745
esophageal adenocarcinoma 6 | 737
gastric cancer 6 | 459
pancreatic carcinoma 6 | 562
pediatric high grade glioma 6 | 1,064
Arthritis 5 | 290
Arthritis, Juvenile 5 | 126
Asthma 5 | 385
Chronic Lymphocytic Leukemia 5 | 262
Depressive disorder 5 | 409
Juvenile arthritis 5 | 126
Kidney cancer 5 | 2,613
active Crohn's disease 5 | 922
adrenocortical carcinoma 5 | 1,428
cystic fibrosis 5 | 1,696
hepatocellular carcinoma 5 | 547
juvenile dermatomyositis 5 | 1,187
lung adenocarcinoma 5 | 2,716
nasopharyngeal carcinoma 5 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
spina bifida 5 | 1,074
urothelial carcinoma 5 | 318
Amyotrophic lateral sclerosis 4 | 451
Autistic Disorder 4 | 364
Breast Neoplasms 4 | 445
Cell Transformation, Neoplastic 4 | 97
Colonic Neoplasms 4 | 142
Contact Dermatitis 4 | 81
Dermatitis, Contact 4 | 71
Liver Cirrhosis, Experimental 4 | 769
Lung disease 4 | 142
Mammary Neoplasms 4 | 425
Mental Depression 4 | 333
Neoplastic Cell Transformation 4 | 89
Osteoporosis 4 | 363
Reperfusion Injury 4 | 86
Rheumatoid arthritis 4 | 1,191
Toxic encephalopathy 4 | 141
active ulcerative colitis 4 | 764
inflammatory breast cancer 4 | 286
non primary Sjogren syndrome sicca 4 | 891
primary pancreatic ductal adenocarcinoma 4 | 1,109
Bipolar Disorder 3 | 666
Duchenne muscular dystrophy 3 | 601
Hypertension 3 | 396
Myocardial Ischemia 3 | 169
Pick disease 3 | 1,894
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
chronic rhinosinusitis 3 | 512
cutaneous lupus erythematosus 3 | 1,057
gastric carcinoma 3 | 807
mucosa-associated lymphoid tissue lymphoma 3 | 484
nephrosclerosis 3 | 333
non diabetic and post-ischemic heart failure 3 | 200
primary Sjogren syndrome 3 | 735
sonic hedgehog group medulloblastoma 3 | 467

Tissue

Digestive Tract 44 | 17,369
Endocrine System 44 | 18,159
Blood and immune system 43 | 16,909
Female tissues 43 | 17,400
Male tissues 43 | 17,142
Skin and soft tissues 43 | 17,230
Cardiovascular System 42 | 15,192
Liver and Pancreas 42 | 16,750
Nervous System 42 | 16,725
Respiratory system 41 | 16,393
Urinary Tract 41 | 16,678

Target Family

Enzyme 24 | 4,145
Kinase 12 | 634
Transcription Factor 7 | 1,400
Non-IDG 2 | 12,091

PathwayCommons: panther Pathway

http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 264 | 264
http://identifiers.org/panther... 197 | 197
http://identifiers.org/panther... 164 | 164
http://identifiers.org/panther... 151 | 151
http://identifiers.org/panther... 150 | 150
http://identifiers.org/panther... 149 | 149
http://identifiers.org/panther... 146 | 146
http://identifiers.org/panther... 124 | 124
http://identifiers.org/panther... 118 | 118
http://identifiers.org/panther... 116 | 116
http://identifiers.org/panther... 115 | 115
http://identifiers.org/panther... 110 | 110
http://identifiers.org/panther... 107 | 107
http://identifiers.org/panther... 104 | 104
http://identifiers.org/panther... 91 | 91
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 86 | 86
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 67 | 67
http://identifiers.org/panther... 65 | 65
http://identifiers.org/panther... 63 | 63
http://identifiers.org/panther... 61 | 61
http://identifiers.org/panther... 60 | 60
http://identifiers.org/panther... 56 | 56
http://identifiers.org/panther... 54 | 54
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 51 | 51
http://identifiers.org/panther... 47 | 47
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 44 | 44
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 41 | 41
http://identifiers.org/panther... 38 | 38
http://identifiers.org/panther... 37 | 37
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 33 | 33
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 31 | 31
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 27 | 27
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 17 | 17
http://identifiers.org/panther... 16 | 16
http://identifiers.org/panther... 15 | 15
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 13 | 13
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 8 | 8
http://identifiers.org/panther... 8 | 8

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
MAP kinase-interacting serine/threonine-protein kinase 1 MKNK1 Tchem Kinase -1.71576 46.7 408
Dual specificity protein phosphatase 26 DUSP26 Tbio Enzyme -2.81752 661.7 128
Dual specificity protein phosphatase 9 DUSP9 Tbio Enzyme -1.15238 17.2 202
Dual specificity protein phosphatase 13 isoform B DUSP13 Tbio Enzyme -1.26330 34.4 180
Dual specificity protein phosphatase 1 DUSP1 Tchem Enzyme -2.88260 810.9 388
MAP kinase-interacting serine/threonine-protein kinase 2 MKNK2 Tchem Kinase -1.32729 19.5 234
Dual specificity protein phosphatase 18 DUSP18 Tbio Enzyme -0.69461 5.47 26
Dual specificity phosphatase DUPD1 DUPD1 Tbio Enzyme -0.43334 2.53 42
Dual specificity protein phosphatase 12 DUSP12 Tbio Enzyme -1.78052 60.2 167
Dual specificity protein phosphatase 16 DUSP16 Tbio Enzyme -1.32944 22.4 159