Development Level

Tbio 17 | 11,445
Tchem 9 | 1,598
Tdark 3 | 6,588

IMPC Phenotype

preweaning lethality, complete... 5 | 979
decreased vertical activity 2 | 208
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal coat appearance 1 | 31
abnormal kidney morphology 1 | 65
abnormal limb morphology 1 | 13
abnormal tail morphology 1 | 25
abnormal vertebrae morphology 1 | 18
abnormal vibrissa morphology 1 | 25
cyanosis 1 | 7
decreased basophil cell number 1 | 16
decreased bone mineral density 1 | 126
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
edema 1 | 59
enlarged heart 1 | 210
enlarged kidney 1 | 14
hemorrhage 1 | 23
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased body weight 1 | 25
increased circulating amylase ... 1 | 25
increased circulating glycerol... 1 | 9
increased grip strength 1 | 41
increased lean body mass 1 | 172
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
respiratory system phenotype 1 | 2

Disease

Carcinoma 24 | 11,493
Cancer 18 | 2,499
glioblastoma 16 | 5,792
osteosarcoma 16 | 7,950
medulloblastoma, large-cell 15 | 6,241
ovarian cancer 13 | 8,520
lung cancer 12 | 4,740
psoriasis 12 | 6,694
Astrocytoma, Pilocytic 11 | 3,081
primitive neuroectodermal tumor 10 | 3,035
Breast Neoplasms 9 | 445
Mammary Neoplasms 9 | 425
atypical teratoid / rhabdoid tumor 9 | 5,112
ependymoma 9 | 4,679
lung carcinoma 9 | 2,843
adult high grade glioma 8 | 3,801
astrocytic glioma 8 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
oligodendroglioma 8 | 2,850
pediatric high grade glioma 8 | 1,064
Alzheimer's disease 7 | 658
Kidney cancer 7 | 2,613
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
invasive ductal carcinoma 7 | 2,951
Breast cancer 6 | 3,578
Rheumatoid arthritis 6 | 1,191
Schizophrenia 6 | 1,160
astrocytoma 6 | 1,146
interstitial cystitis 6 | 2,312
juvenile dermatomyositis 6 | 1,187
malignant mesothelioma 6 | 3,232
pancreatic cancer 6 | 2,398
subependymal giant cell astrocytoma 6 | 2,287
tuberculosis 6 | 2,010
Alagille syndrome 5 | 15
Brachydactyly 5 | 156
Carcinoma, Pancreatic Ductal 5 | 20
Failure to gain weight 5 | 365
Pediatric failure to thrive 5 | 365
Short distal phalanges 5 | 50
Spondylocostal dysostosis 5 | 12
group 3 medulloblastoma 5 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
non-small cell lung cancer 5 | 2,890
Acquired scoliosis 4 | 281
Cadasil 4 | 10
Carcinoma, Squamous Cell 4 | 110
Cataract 4 | 297
Cerebrovascular disease 4 | 238
Curvature of spine 4 | 282
Dementia 4 | 175
Down syndrome 4 | 499
Duchenne muscular dystrophy 4 | 601
Esophageal Squamous Cell Carcinoma 4 | 77
Fetal Growth Retardation 4 | 189
Hydrocephalus 4 | 152
Lens Opacities 4 | 231
Liver cancer 4 | 604
Multiple Sclerosis 4 | 540
Short neck 4 | 140
Short stature 4 | 531
Skin Neoplasms 4 | 69
Squamous cell carcinoma of esophagus 4 | 77
Strabismus 4 | 270
Tetralogy of Fallot 4 | 63
dermatomyositis 4 | 966
gastric carcinoma 4 | 807
lung adenocarcinoma 4 | 2,716
sonic hedgehog group medulloblastoma 4 | 467
ulcerative colitis 4 | 1,819
Abnormality of pulmonary valve 3 | 23
Adenoid Cystic Carcinoma 3 | 99
Amyotrophic lateral sclerosis 3 | 451
Aplasia Cutis Congenita 3 | 14
Carcinoma, Adenoid Cystic 3 | 99
Congenital scar 3 | 13
Craniofacial Abnormalities 3 | 151
Hypertension 3 | 396
Immune system cancer 3 | 140
Liver Cirrhosis 3 | 181
Long narrow head 3 | 75
Lung Neoplasms 3 | 232
Lymphoid leukemia 3 | 160
Narrow cranium shape 3 | 75
Narrow head shape 3 | 75
Narrow skull shape 3 | 75
Neurodegenerative disease 3 | 414
Pick disease 3 | 1,894
Sparse hair 3 | 59
Syndactyly of fingers 3 | 48
Thin, sparse hair 3 | 59
Turridolichocephaly 3 | 75
acute quadriplegic myopathy 3 | 1,158
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
cystic fibrosis 3 | 1,696
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pituitary cancer 3 | 1,972
primary pancreatic ductal adenocarcinoma 3 | 1,109
progressive supranuclear palsy 3 | 676
spina bifida 3 | 1,074

Tissue

Digestive Tract 29 | 17,369
Endocrine System 29 | 18,159
Blood and immune system 28 | 16,909
Liver and Pancreas 28 | 16,750
Skin and soft tissues 28 | 17,230
Cardiovascular System 27 | 15,192
Female tissues 27 | 17,400
Male tissues 27 | 17,142
Nervous System 27 | 16,725
Respiratory system 27 | 16,393
Urinary Tract 27 | 16,678

Target Family

Non-IDG 17 | 12,091
Enzyme 9 | 4,145
Transcription Factor 3 | 1,400

PathwayCommons: panther Pathway

http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 264 | 264
http://identifiers.org/panther... 197 | 197
http://identifiers.org/panther... 164 | 164
http://identifiers.org/panther... 151 | 151
http://identifiers.org/panther... 150 | 150
http://identifiers.org/panther... 149 | 149
http://identifiers.org/panther... 146 | 146
http://identifiers.org/panther... 124 | 124
http://identifiers.org/panther... 118 | 118
http://identifiers.org/panther... 116 | 116
http://identifiers.org/panther... 115 | 115
http://identifiers.org/panther... 110 | 110
http://identifiers.org/panther... 107 | 107
http://identifiers.org/panther... 104 | 104
http://identifiers.org/panther... 91 | 91
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 86 | 86
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 67 | 67
http://identifiers.org/panther... 65 | 65
http://identifiers.org/panther... 63 | 63
http://identifiers.org/panther... 61 | 61
http://identifiers.org/panther... 60 | 60
http://identifiers.org/panther... 56 | 56
http://identifiers.org/panther... 54 | 54
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 51 | 51
http://identifiers.org/panther... 47 | 47
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 44 | 44
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 41 | 41
http://identifiers.org/panther... 38 | 38
http://identifiers.org/panther... 37 | 37
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 33 | 33
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 31 | 31
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 27 | 27
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 17 | 17
http://identifiers.org/panther... 16 | 16
http://identifiers.org/panther... 15 | 15
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 13 | 13
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 8 | 8
http://identifiers.org/panther... 8 | 8

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neuralized-like protein 2 NEURL2 Tdark Non-IDG -0.41285 3.16 58
E3 ubiquitin-protein ligase NEURL1 NEURL1 Tbio Enzyme -1.09204 13.1 165
Delta-like protein 3 DLL3 Tbio Non-IDG -1.68978 48.6 214
Ligand of Numb protein X 2 LNX2 Tbio Non-IDG -1.32399 21.7 135
Recombining binding protein suppressor of hairless-like protein RBPJL Tbio Transcription Factor -1.54648 33.1 104
Beta-1,3-N-acetylglucosaminyltransferase manic fringe MFNG Tbio Enzyme -0.83827 6.67 114
Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe LFNG Tbio Enzyme -1.50535 29.8 220
Presenilin-1 PSEN1 Tchem Enzyme -3.53128 3394.7 677
GDP-fucose protein O-fucosyltransferase 1 POFUT1 Tbio Enzyme -1.53099 37.5 157
Disintegrin and metalloproteinase domain-containing protein 10 ADAM10 Tchem Enzyme -2.64652 422.4 384