Development Level

Tbio 57 | 11,445
Tclin 11 | 613
Tchem 9 | 1,598
Tdark 9 | 6,588

Collection

Ion Channel: IDG Consortium (T... 4 | 99

IMPC Phenotype

preweaning lethality, complete... 8 | 979
increased lean body mass 4 | 172
preweaning lethality, incomple... 4 | 499
abnormal behavior 3 | 298
decreased body weight 3 | 161
embryonic lethality prior to t... 3 | 278
increased or absent threshold ... 3 | 101
abnormal behavioral response t... 2 | 66
abnormal bone structure 2 | 187
abnormal coat-hair pigmentatio... 2 | 64
abnormal placenta size 2 | 20
abnormal sleep behavior 2 | 70
convulsive seizures 2 | 13
decreased circulating insulin ... 2 | 76
decreased leukocyte cell numbe... 2 | 73
decreased total body fat amoun... 2 | 207
embryonic growth retardation 2 | 106
hyperactivity 2 | 148
increased bone mineral content 2 | 108
increased bone mineral density 2 | 72
increased circulating sodium l... 2 | 71
increased total body fat amoun... 2 | 134
pallor 2 | 34
persistence of hyaloid vascula... 2 | 33
prenatal lethality prior to he... 2 | 87
abnormal bone mineralization 1 | 38
abnormal cornea morphology 1 | 31
abnormal digit morphology 1 | 10
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal hair growth 1 | 10
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal limb bud morphology 1 | 17
abnormal locomotor activation 1 | 16
abnormal motor learning 1 | 3
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
abnormal skin coloration 1 | 25
abnormal vocalization 1 | 21
abnormal whole-body plethysmog... 1 | 4
absent pinna reflex 1 | 23
absent startle reflex 1 | 24
brachydactyly 1 | 19
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
corneal opacity 1 | 32
decreased anxiety-related resp... 1 | 12
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating amylase ... 1 | 28
decreased circulating chloride... 1 | 30
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased circulating iron lev... 1 | 32
decreased circulating triglyce... 1 | 79
decreased exploration in new e... 1 | 11
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased urine creatinine lev... 1 | 3
edema 1 | 59
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
fused cornea and lens 1 | 5
fused phalanges 1 | 1
hemorrhage 1 | 23
impaired pupillary reflex 1 | 26
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased circulating triglyce... 1 | 42
increased erythrocyte cell num... 1 | 39
increased exploration in new e... 1 | 8
increased grip strength 1 | 41
increased heart rate variabili... 1 | 7
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 36
increased startle reflex 1 | 112
increased thermal nociceptive ... 1 | 9
increased urine magnesium leve... 1 | 2
increased vertical activity 1 | 24
pale liver 1 | 6
pale yolk sac 1 | 25
prolonged PR interval 1 | 15
stereotypic behavior 1 | 3
syndactyly 1 | 23
thrombocytosis 1 | 27
tremors 1 | 39
trunk curl 1 | 16

Disease

Carcinoma 68 | 11,493
psoriasis 41 | 6,694
osteosarcoma 33 | 7,950
ovarian cancer 32 | 8,520
Kidney cancer 31 | 2,613
glioblastoma 24 | 5,792
medulloblastoma, large-cell 24 | 6,241
ependymoma 23 | 4,679
malignant mesothelioma 21 | 3,232
Autosomal recessive predisposition 20 | 1,442
adult high grade glioma 20 | 3,801
Astrocytoma, Pilocytic 19 | 3,081
Schizophrenia 19 | 1,160
lung cancer 19 | 4,740
lung carcinoma 19 | 2,843
atypical teratoid / rhabdoid tumor 18 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,955
Breast cancer 15 | 3,578
Nicotine dependence 15 | 54
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,989
lung adenocarcinoma 15 | 2,716
Blepharoptosis 14 | 231
Seizures 14 | 596
acute quadriplegic myopathy 13 | 1,158
group 3 medulloblastoma 13 | 4,104
non-small cell lung cancer 13 | 2,890
interstitial cystitis 12 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
oligodendroglioma 12 | 2,850
primitive neuroectodermal tumor 12 | 3,035
Epilepsy 11 | 792
Liver cancer 11 | 604
cystic fibrosis 11 | 1,696
group 4 medulloblastoma 11 | 1,855
pituitary cancer 11 | 1,972
Bipolar Disorder 10 | 666
Intellectual disability 10 | 1,016
Pick disease 10 | 1,894
astrocytic glioma 10 | 2,597
invasive ductal carcinoma 10 | 2,951
subependymal giant cell astrocytoma 10 | 2,287
ulcerative colitis 10 | 1,819
Alzheimer's disease 9 | 658
Byzanthine arch palate 9 | 194
Deglutition Disorders 9 | 132
Melanoma 9 | 711
Neuropathy 9 | 261
Nonsyndromic deafness 9 | 142
Sensorineural hearing loss 9 | 106
ductal carcinoma in situ 9 | 1,745
Congenital myasthenic syndrome 8 | 25
Muscle hypotonia 8 | 571
Ophthalmoplegia 8 | 106
Prenatal onset 8 | 139
colon cancer 8 | 1,478
juvenile dermatomyositis 8 | 1,187
pancreatic cancer 8 | 2,398
Arthrogryposis 7 | 54
Autistic Disorder 7 | 364
Cognitive delay 7 | 608
Feeding difficulties 7 | 127
Frontal lobe epilepsy 7 | 10
Global developmental delay 7 | 608
Infantile onset 7 | 238
Liver Cirrhosis, Experimental 7 | 769
Long face 7 | 71
Mental Depression 7 | 333
Mental and motor retardation 7 | 608
Neonatal Hypotonia 7 | 64
Skin cancer 7 | 469
diabetes mellitus 7 | 1,728
pediatric high grade glioma 7 | 1,064
Acquired scoliosis 6 | 281
Amyotrophic lateral sclerosis 6 | 451
Attention deficit hyperactivity disorder 6 | 278
Bell Palsy 6 | 58
Curvature of spine 6 | 282
Depressive disorder 6 | 409
Distal arthrogryposis 6 | 42
Down syndrome 6 | 499
Duchenne muscular dystrophy 6 | 601
Dull intelligence 6 | 645
Endometrial cancer 6 | 311
Facial Paresis 6 | 59
Facial muscle weakness of muscles innervated by CN VII 6 | 58
Highly variable severity 6 | 157
Low intelligence 6 | 645
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Multiple pterygium syndrome 6 | 18
Orbital separation excessive 6 | 244
Parkinson's disease 6 | 392
Polyhydramnios 6 | 108
Poor school performance 6 | 645
Respiratory Insufficiency 6 | 132
Short stature 6 | 531
Variable expressivity 6 | 157
breast carcinoma 6 | 1,638
cutaneous lupus erythematosus 6 | 1,057
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962

Tissue

Endocrine System 84 | 18,159
Skin and soft tissues 82 | 17,230
Digestive Tract 80 | 17,369
Male tissues 78 | 17,142
Female tissues 77 | 17,400
Blood and immune system 75 | 16,909
Liver and Pancreas 74 | 16,750
Nervous System 74 | 16,725
Urinary Tract 71 | 16,678
Respiratory system 69 | 16,393
Cardiovascular System 67 | 15,192

Target Family

Non-IDG 61 | 12,091
Ion Channel 16 | 344
Transporter 4 | 473
Enzyme 3 | 4,145
Kinase 2 | 634

PathwayCommons: panther Pathway

http://identifiers.org/panther... 86 | 86
http://identifiers.org/panther... 264 | 264
http://identifiers.org/panther... 197 | 197
http://identifiers.org/panther... 164 | 164
http://identifiers.org/panther... 151 | 151
http://identifiers.org/panther... 150 | 150
http://identifiers.org/panther... 149 | 149
http://identifiers.org/panther... 146 | 146
http://identifiers.org/panther... 124 | 124
http://identifiers.org/panther... 118 | 118
http://identifiers.org/panther... 116 | 116
http://identifiers.org/panther... 115 | 115
http://identifiers.org/panther... 110 | 110
http://identifiers.org/panther... 107 | 107
http://identifiers.org/panther... 104 | 104
http://identifiers.org/panther... 91 | 91
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 67 | 67
http://identifiers.org/panther... 65 | 65
http://identifiers.org/panther... 63 | 63
http://identifiers.org/panther... 61 | 61
http://identifiers.org/panther... 60 | 60
http://identifiers.org/panther... 56 | 56
http://identifiers.org/panther... 54 | 54
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 51 | 51
http://identifiers.org/panther... 47 | 47
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 44 | 44
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 41 | 41
http://identifiers.org/panther... 38 | 38
http://identifiers.org/panther... 37 | 37
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 33 | 33
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 31 | 31
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 27 | 27
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 17 | 17
http://identifiers.org/panther... 16 | 16
http://identifiers.org/panther... 15 | 15
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 13 | 13
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 8 | 8
http://identifiers.org/panther... 8 | 8

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Unconventional myosin-XV MYO15A Tbio Non-IDG -1.64094 42.8 15
Myosin-13 MYH13 Tbio Non-IDG -1.26079 16.6 12
Myosin-2 MYH2 Tbio Non-IDG -2.14128 114.9 63
Myosin-4 MYH4 Tbio Non-IDG -1.81214 51.8 52
cTAGE family member 15 CTAGE15 Tdark Non-IDG 0.00000 12
Myosin-IIIb MYO3B Tbio Kinase -0.73450 5.14 127
CHRNA7-FAM7A fusion protein CHRFAM7A Tbio Non-IDG -1.79939 87.7 87
Unconventional myosin-VIIa MYO7A Tbio Non-IDG -2.14713 133.5 129
Unconventional myosin-IXa MYO9A Tdark Non-IDG -0.82985 8.76 21
Myosin-15 MYH15 Tbio Non-IDG -0.95780 9.01 40