Development Level

Tbio 34 | 11,445
Tchem 10 | 1,598
Tdark 5 | 6,588
Tclin 4 | 613

Collection

Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

abnormal behavior 4 | 298
preweaning lethality, complete... 4 | 979
hyperactivity 3 | 148
increased bone mineral content 3 | 108
preweaning lethality, incomple... 3 | 499
decreased bone mineral content 2 | 151
decreased circulating insulin ... 2 | 76
decreased total body fat amoun... 2 | 207
increased bone mineral density 2 | 72
increased lean body mass 2 | 172
abnormal bone structure 1 | 187
abnormal epididymis morphology 1 | 42
abnormal hair growth 1 | 10
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
decreased circulating chloride... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating iron lev... 1 | 32
decreased fasted circulating g... 1 | 65
decreased respiratory quotient 1 | 16
decreased startle reflex 1 | 75
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
enlarged heart 1 | 210
enlarged spleen 1 | 41
impaired righting response 1 | 26
increased circulating creatini... 1 | 38
increased circulating triglyce... 1 | 42
increased exploration in new e... 1 | 8
increased grip strength 1 | 41
increased mean corpuscular hem... 1 | 36
limb grasping 1 | 41
thrombocytosis 1 | 27

Disease

Carcinoma 31 | 11,493
medulloblastoma, large-cell 30 | 6,241
glioblastoma 27 | 5,792
ependymoma 25 | 4,679
osteosarcoma 25 | 7,950
ovarian cancer 25 | 8,520
psoriasis 25 | 6,694
atypical teratoid / rhabdoid tumor 22 | 5,112
Astrocytoma, Pilocytic 21 | 3,081
group 3 medulloblastoma 21 | 4,104
oligodendroglioma 21 | 2,850
adult high grade glioma 18 | 3,801
astrocytic glioma 18 | 2,597
lung carcinoma 16 | 2,843
primitive neuroectodermal tumor 16 | 3,035
subependymal giant cell astrocytoma 15 | 2,287
Pick disease 13 | 1,894
Schizophrenia 12 | 1,160
lung cancer 12 | 4,740
malignant mesothelioma 12 | 3,232
pancreatic cancer 11 | 2,398
Breast cancer 9 | 3,578
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
non-small cell lung cancer 9 | 2,890
Depressive disorder 8 | 409
interstitial cystitis 8 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
invasive ductal carcinoma 8 | 2,951
lung adenocarcinoma 8 | 2,716
Autosomal recessive predisposition 7 | 1,442
Intellectual disability 7 | 1,016
Parkinson's disease 7 | 392
acute quadriplegic myopathy 7 | 1,158
colon cancer 7 | 1,478
group 4 medulloblastoma 7 | 1,855
juvenile dermatomyositis 7 | 1,187
pituitary cancer 7 | 1,972
Alzheimer's disease 6 | 658
Bipolar Disorder 6 | 666
Carney complex 6 | 25
Duchenne muscular dystrophy 6 | 601
Mental Depression 6 | 333
Multiple myeloma 6 | 1,332
Neuropathy 6 | 261
Tetanus 6 | 68
cystic fibrosis 6 | 1,696
primary pancreatic ductal adenocarcinoma 6 | 1,109
ulcerative colitis 6 | 1,819
Cognitive delay 5 | 608
Down syndrome 5 | 499
Epilepsy 5 | 792
Global developmental delay 5 | 608
Liver Cirrhosis, Experimental 5 | 769
Mental and motor retardation 5 | 608
Obesity 5 | 678
Rheumatoid arthritis 5 | 1,191
Seizures 5 | 596
Waldenstrons macroglobulinemia 5 | 765
active Crohn's disease 5 | 922
astrocytoma 5 | 1,146
breast carcinoma 5 | 1,638
dermatomyositis 5 | 966
diabetes mellitus 5 | 1,728
ductal carcinoma in situ 5 | 1,745
pancreatic carcinoma 5 | 562
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Blepharoptosis 4 | 231
Brain disease 4 | 96
Congenital Myasthenic Syndromes, Presynaptic 4 | 8
Congenital myasthenic syndrome 4 | 25
Dementia 4 | 175
Hypertensive disease 4 | 292
Major Depressive Disorder 4 | 301
Osteoporosis 4 | 363
Primary pigmented nodular adrenocortical disease 4 | 13
Short stature 4 | 531
active ulcerative colitis 4 | 764
adrenocortical carcinoma 4 | 1,428
gastric cancer 4 | 459
non primary Sjogren syndrome sicca 4 | 891
tuberculosis 4 | 2,010
Amyotrophic lateral sclerosis 3 | 451
Attention deficit hyperactivity disorder 3 | 278
Concave bridge of nose 3 | 195
Depressed nasal bridge 3 | 195
Depressed nasal root/bridge 3 | 195
Failure to gain weight 3 | 365
Kidney cancer 3 | 2,613
Mood Disorders 3 | 184
Neurodegenerative disease 3 | 414
Pediatric failure to thrive 3 | 365
Prostatic Neoplasms 3 | 495
Toxic encephalopathy 3 | 141
Unipolar Depression 3 | 250
aldosterone-producing adenoma 3 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
cutaneous lupus erythematosus 3 | 1,057
fibroadenoma 3 | 559
pediatric high grade glioma 3 | 1,064

Tissue

Endocrine System 52 | 18,159
Digestive Tract 51 | 17,369
Nervous System 51 | 16,725
Skin and soft tissues 51 | 17,230
Female tissues 49 | 17,400
Liver and Pancreas 49 | 16,750
Male tissues 49 | 17,142
Respiratory system 48 | 16,393
Blood and immune system 47 | 16,909
Urinary Tract 45 | 16,678
Cardiovascular System 43 | 15,192

Target Family

Non-IDG 32 | 12,091
Enzyme 8 | 4,145
Ion Channel 4 | 344
Kinase 4 | 634
Transporter 3 | 473
GPCR 2 | 408

PathwayCommons: panther Pathway

http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 264 | 264
http://identifiers.org/panther... 197 | 197
http://identifiers.org/panther... 164 | 164
http://identifiers.org/panther... 151 | 151
http://identifiers.org/panther... 150 | 150
http://identifiers.org/panther... 149 | 149
http://identifiers.org/panther... 146 | 146
http://identifiers.org/panther... 124 | 124
http://identifiers.org/panther... 118 | 118
http://identifiers.org/panther... 116 | 116
http://identifiers.org/panther... 115 | 115
http://identifiers.org/panther... 110 | 110
http://identifiers.org/panther... 107 | 107
http://identifiers.org/panther... 104 | 104
http://identifiers.org/panther... 91 | 91
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 86 | 86
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 67 | 67
http://identifiers.org/panther... 65 | 65
http://identifiers.org/panther... 63 | 63
http://identifiers.org/panther... 61 | 61
http://identifiers.org/panther... 60 | 60
http://identifiers.org/panther... 56 | 56
http://identifiers.org/panther... 54 | 54
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 51 | 51
http://identifiers.org/panther... 47 | 47
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 44 | 44
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 41 | 41
http://identifiers.org/panther... 38 | 38
http://identifiers.org/panther... 37 | 37
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 33 | 33
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 31 | 31
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 27 | 27
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 17 | 17
http://identifiers.org/panther... 16 | 16
http://identifiers.org/panther... 15 | 15
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 13 | 13
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 8 | 8
http://identifiers.org/panther... 8 | 8

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adenylate cyclase type 10 ADCY10 Tchem Enzyme -3.13751 1324.4 108
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 GNG8 Tdark Non-IDG -2.17483 154.8 34
cAMP-dependent protein kinase catalytic subunit PRKX PRKX Tchem Kinase -1.17196 28.7 183
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 GNG10 Tdark Non-IDG 0.16 0.62 18
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 GNG5 Tbio Non-IDG -0.57807 4.05 87
Choline O-acetyltransferase CHAT Tchem Enzyme -3.40175 2597.2 436
G protein-activated inward rectifier potassium channel 1 KCNJ3 Tchem Ion Channel -2.34432 217.2 267
Sodium- and chloride-dependent creatine transporter 1 SLC6A8 Tbio Transporter -2.09955 121.8 133
Acetylcholinesterase ACHE Tclin Enzyme -3.49768 2470.5 505
Guanine nucleotide-binding protein G(o) subunit alpha GNAO1 Tbio Non-IDG -2.24331 158.7 195