Development Level

Tbio 9 | 11,445
Tclin 8 | 613
Tchem 7 | 1,598

Collection

Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

abnormal bone structure 2 | 187
decreased body weight 2 | 161
decreased circulating triglyce... 2 | 79
increased startle reflex 2 | 112
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal gallbladder morpholog... 1 | 1
abnormal locomotor behavior 1 | 24
decreased circulating amylase ... 1 | 28
decreased circulating phosphat... 1 | 27
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased heart weight 1 | 27
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged gallbladder 1 | 2
hydrometra 1 | 53
hypoactivity 1 | 132
increased bone mineral content 1 | 108
increased circulating calcium ... 1 | 34
increased fasted circulating g... 1 | 76
increased lean body mass 1 | 172
increased or absent threshold ... 1 | 101
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97
small epididymis 1 | 3
small superior vagus ganglion 1 | 74
vertebral fusion 1 | 23

Disease

Carcinoma 20 | 11,493
atypical teratoid / rhabdoid tumor 18 | 5,112
glioblastoma 17 | 5,792
medulloblastoma, large-cell 17 | 6,241
psoriasis 16 | 6,694
adult high grade glioma 15 | 3,801
primitive neuroectodermal tumor 15 | 3,035
ependymoma 13 | 4,679
astrocytic glioma 12 | 2,597
oligodendroglioma 12 | 2,850
Astrocytoma, Pilocytic 11 | 3,081
Schizophrenia 11 | 1,160
osteosarcoma 11 | 7,950
ovarian cancer 11 | 8,520
group 3 medulloblastoma 10 | 4,104
Epilepsy 9 | 792
Kidney cancer 9 | 2,613
Parkinson's disease 9 | 392
Bipolar Disorder 8 | 666
Breast cancer 8 | 3,578
Intellectual disability 8 | 1,016
Melanoma 8 | 711
Pick disease 8 | 1,894
lung carcinoma 8 | 2,843
subependymal giant cell astrocytoma 8 | 2,287
Autistic Disorder 7 | 364
Depressive disorder 7 | 409
Toxic encephalopathy 7 | 141
lung cancer 7 | 4,740
Alcoholic Intoxication, Chronic 6 | 289
Alcoholism 6 | 45
Arteriosclerotic Parkinsonism 6 | 8
Attention deficit hyperactivity disorder 6 | 278
Dull intelligence 6 | 645
Extrapyramidal disease 6 | 8
General anesthesia 6 | 53
Influenza A Prevention 6 | 7
Influenza due to Influenza A virus 6 | 7
Local anesthesia 6 | 40
Low intelligence 6 | 645
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Parkinsonism 6 | 18
Poor school performance 6 | 645
Postencephalitic parkinsonism 6 | 12
colon cancer 6 | 1,478
lung adenocarcinoma 6 | 2,716
Autosomal recessive predisposition 5 | 1,442
Skin cancer 5 | 469
group 4 medulloblastoma 5 | 1,855
tuberculosis 5 | 2,010
Carney complex 4 | 25
Cognitive delay 4 | 608
Global developmental delay 4 | 608
Lennox-Gastaut syndrome 4 | 34
Major Depressive Disorder 4 | 301
Mental Depression 4 | 333
Mental and motor retardation 4 | 608
Moderate to Severe Alzheimer's Type Dementia 4 | 5
Seizures 4 | 596
Simple partial seizure 4 | 26
Unipolar Depression 4 | 250
Waldenstrons macroglobulinemia 4 | 765
active ulcerative colitis 4 | 764
malignant mesothelioma 4 | 3,232
medulloblastoma 4 | 720
pancreatic cancer 4 | 2,398
ulcerative colitis 4 | 1,819
Alcohol dependence 3 | 107
Alzheimer's disease 3 | 658
Amyotrophic lateral sclerosis 3 | 451
Cancer 3 | 2,499
Cocaine-Related Disorders 3 | 92
Crohn's disease 3 | 321
Down syndrome 3 | 499
Huntington's disease 3 | 76
Liver cancer 3 | 604
McCune Albright syndrome 3 | 19
Mood swings 3 | 77
Muscle hypotonia 3 | 571
Neurodegenerative disease 3 | 414
Primary pigmented nodular adrenocortical disease 3 | 13
Pseudohypoparathyroidism 3 | 18
Rheumatoid arthritis 3 | 1,191
Short stature 3 | 531
Uveal melanoma 3 | 20
active Crohn's disease 3 | 922
diabetes mellitus 3 | 1,728
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
non-small cell lung cancer 3 | 2,890
progressive supranuclear palsy 3 | 676
Highly variable severity 2 | 157
Hyperreflexia 2 | 209
Increased susceptibility to fractures 2 | 21
Neurogenic Muscular Atrophy 2 | 139
Retinal Detachment 2 | 51
Variable expressivity 2 | 157
muscle degeneration 2 | 139

Tissue

Endocrine System 24 | 18,159
Nervous System 23 | 16,725
Female tissues 22 | 17,400
Liver and Pancreas 22 | 16,750
Male tissues 22 | 17,142
Skin and soft tissues 22 | 17,230
Urinary Tract 22 | 16,678
Blood and immune system 21 | 16,909
Digestive Tract 21 | 17,369
Respiratory system 21 | 16,393
Cardiovascular System 19 | 15,192

Target Family

Ion Channel 9 | 344
Kinase 5 | 634
Non-IDG 5 | 12,091
Enzyme 3 | 4,145
GPCR 2 | 408

PathwayCommons: panther Pathway

http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 264 | 264
http://identifiers.org/panther... 197 | 197
http://identifiers.org/panther... 164 | 164
http://identifiers.org/panther... 151 | 151
http://identifiers.org/panther... 150 | 150
http://identifiers.org/panther... 149 | 149
http://identifiers.org/panther... 146 | 146
http://identifiers.org/panther... 124 | 124
http://identifiers.org/panther... 118 | 118
http://identifiers.org/panther... 116 | 116
http://identifiers.org/panther... 115 | 115
http://identifiers.org/panther... 110 | 110
http://identifiers.org/panther... 107 | 107
http://identifiers.org/panther... 104 | 104
http://identifiers.org/panther... 91 | 91
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 86 | 86
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 67 | 67
http://identifiers.org/panther... 65 | 65
http://identifiers.org/panther... 63 | 63
http://identifiers.org/panther... 61 | 61
http://identifiers.org/panther... 60 | 60
http://identifiers.org/panther... 56 | 56
http://identifiers.org/panther... 54 | 54
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 51 | 51
http://identifiers.org/panther... 47 | 47
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 44 | 44
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 41 | 41
http://identifiers.org/panther... 38 | 38
http://identifiers.org/panther... 37 | 37
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 33 | 33
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 31 | 31
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 27 | 27
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 17 | 17
http://identifiers.org/panther... 16 | 16
http://identifiers.org/panther... 15 | 15
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 13 | 13
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 8 | 8
http://identifiers.org/panther... 8 | 8

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Guanine nucleotide-binding protein subunit alpha-11 GNA11 Tbio Non-IDG -2.80484 555.1 184
Protein kinase C beta type PRKCB Tchem Kinase -2.00437 93.5 598
cAMP-dependent protein kinase catalytic subunit PRKX PRKX Tchem Kinase -1.17196 28.7 183
Guanine nucleotide-binding protein G(q) subunit alpha GNAQ Tbio Non-IDG -2.73429 514.5 206
Metabotropic glutamate receptor 5 GRM5 Tchem GPCR -3.12353 1370.3 396
Protein lifeguard 1 GRINA Tbio Non-IDG -0.91904 8.30 147
Glutamate receptor ionotropic, kainate 5 GRIK5 Tclin Ion Channel -2.11616 127.3 179
Metabotropic glutamate receptor 1 GRM1 Tchem GPCR -3.05662 1115.6 490
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 PLCB4 Tbio Enzyme -1.77110 57.7 19
Glutamate receptor ionotropic, NMDA 3A GRIN3A Tclin Ion Channel -1.89138 80.5 24