Development Level

Tbio 28 | 11,445
Tchem 17 | 1,598
Tclin 16 | 613
Tdark 4 | 6,588

Collection

Ion Channel: IDG Consortium (T... 2 | 99
Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

preweaning lethality, incomple... 4 | 499
preweaning lethality, complete... 3 | 979
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
abnormal epididymis morphology 2 | 42
decreased fasted circulating g... 2 | 65
hyperactivity 2 | 148
increased circulating triglyce... 2 | 42
limb grasping 2 | 41
abnormal bone mineralization 1 | 38
abnormal eye morphology 1 | 68
abnormal gait 1 | 69
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
cataract 1 | 92
decreased body weight 1 | 161
decreased circulating insulin ... 1 | 76
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased neutrophil cell numb... 1 | 42
decreased total body fat amoun... 1 | 207
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
enlarged heart 1 | 210
enlarged spleen 1 | 41
impaired pupillary reflex 1 | 26
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alanine ... 1 | 13
increased circulating chloride... 1 | 41
increased circulating iron lev... 1 | 30
increased circulating sodium l... 1 | 71
increased heart rate 1 | 23
increased heart weight 1 | 62
increased kidney weight 1 | 6
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 36
increased mean platelet volume 1 | 45
increased startle reflex 1 | 112
mydriasis 1 | 6

Disease

Carcinoma 46 | 11,493
medulloblastoma, large-cell 43 | 6,241
glioblastoma 42 | 5,792
atypical teratoid / rhabdoid tumor 39 | 5,112
ependymoma 36 | 4,679
group 3 medulloblastoma 33 | 4,104
oligodendroglioma 33 | 2,850
Schizophrenia 32 | 1,160
adult high grade glioma 32 | 3,801
Astrocytoma, Pilocytic 30 | 3,081
osteosarcoma 29 | 7,950
primitive neuroectodermal tumor 29 | 3,035
astrocytic glioma 28 | 2,597
Bipolar Disorder 27 | 666
psoriasis 27 | 6,694
ovarian cancer 25 | 8,520
Kidney cancer 22 | 2,613
lung carcinoma 22 | 2,843
Epilepsy 21 | 792
Pick disease 21 | 1,894
subependymal giant cell astrocytoma 21 | 2,287
lung cancer 18 | 4,740
Intellectual disability 15 | 1,016
Parkinson's disease 15 | 392
Depressive disorder 14 | 409
Breast cancer 13 | 3,578
Mental Depression 13 | 333
Toxic encephalopathy 13 | 141
malignant mesothelioma 12 | 3,232
Alcoholic Intoxication, Chronic 11 | 289
Autistic Disorder 11 | 364
Lennox-Gastaut syndrome 11 | 34
Liver cancer 11 | 604
Major Depressive Disorder 11 | 301
Simple partial seizure 11 | 26
Alzheimer's disease 10 | 658
General anesthesia 10 | 53
Local anesthesia 10 | 40
pituitary cancer 10 | 1,972
Epilepsy characterized by intractable complex partial seizures 9 | 28
Melanoma 9 | 711
Migraine Prevention 9 | 23
Tonic-clonic epilepsy 9 | 47
Unipolar Depression 9 | 250
group 4 medulloblastoma 9 | 1,855
non primary Sjogren syndrome sicca 9 | 891
Amyotrophic lateral sclerosis 8 | 451
Attention deficit hyperactivity disorder 8 | 278
Skin cancer 8 | 469
lung adenocarcinoma 8 | 2,716
pancreatic cancer 8 | 2,398
Alcohol dependence 7 | 107
Dull intelligence 7 | 645
Low intelligence 7 | 645
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Poor school performance 7 | 645
Seizures 7 | 596
astrocytoma 7 | 1,146
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
invasive ductal carcinoma 7 | 2,951
pediatric high grade glioma 7 | 1,064
Alcoholism 6 | 45
Arteriosclerotic Parkinsonism 6 | 8
Autosomal recessive predisposition 6 | 1,442
Carney complex 6 | 25
Cognitive delay 6 | 608
Duchenne muscular dystrophy 6 | 601
Extrapyramidal disease 6 | 8
Global developmental delay 6 | 608
Influenza A Prevention 6 | 7
Influenza due to Influenza A virus 6 | 7
Mental and motor retardation 6 | 608
Multiple myeloma 6 | 1,332
Neurodegenerative disease 6 | 414
Parkinsonism 6 | 18
Postencephalitic parkinsonism 6 | 12
Psychotic Disorders 6 | 151
Rheumatoid arthritis 6 | 1,191
Tetanus 6 | 68
acute quadriplegic myopathy 6 | 1,158
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
primary pancreatic ductal adenocarcinoma 6 | 1,109
Cocaine-Related Disorders 5 | 92
Huntington's disease 5 | 76
Waldenstrons macroglobulinemia 5 | 765
cystic fibrosis 5 | 1,696
juvenile dermatomyositis 5 | 1,187
non-small cell lung cancer 5 | 2,890
ulcerative colitis 5 | 1,819
Down syndrome 4 | 499
Vascular disease 4 | 319
breast carcinoma 4 | 1,638
colon cancer 4 | 1,478
diabetes mellitus 4 | 1,728
ductal carcinoma in situ 4 | 1,745
gastric carcinoma 4 | 807
interstitial cystitis 4 | 2,312
tuberculosis 4 | 2,010

Tissue

Endocrine System 65 | 18,159
Nervous System 64 | 16,725
Female tissues 63 | 17,400
Skin and soft tissues 63 | 17,230
Digestive Tract 62 | 17,369
Male tissues 62 | 17,142
Blood and immune system 61 | 16,909
Liver and Pancreas 61 | 16,750
Urinary Tract 59 | 16,678
Respiratory system 58 | 16,393
Cardiovascular System 53 | 15,192

Target Family

Non-IDG 25 | 12,091
Ion Channel 19 | 344
GPCR 6 | 408
Transporter 6 | 473
Enzyme 5 | 4,145
Kinase 4 | 634

PathwayCommons: panther Pathway

http://identifiers.org/panther... 65 | 65
http://identifiers.org/panther... 264 | 264
http://identifiers.org/panther... 197 | 197
http://identifiers.org/panther... 164 | 164
http://identifiers.org/panther... 151 | 151
http://identifiers.org/panther... 150 | 150
http://identifiers.org/panther... 149 | 149
http://identifiers.org/panther... 146 | 146
http://identifiers.org/panther... 124 | 124
http://identifiers.org/panther... 118 | 118
http://identifiers.org/panther... 116 | 116
http://identifiers.org/panther... 115 | 115
http://identifiers.org/panther... 110 | 110
http://identifiers.org/panther... 107 | 107
http://identifiers.org/panther... 104 | 104
http://identifiers.org/panther... 91 | 91
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 86 | 86
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 67 | 67
http://identifiers.org/panther... 63 | 63
http://identifiers.org/panther... 61 | 61
http://identifiers.org/panther... 60 | 60
http://identifiers.org/panther... 56 | 56
http://identifiers.org/panther... 54 | 54
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 51 | 51
http://identifiers.org/panther... 47 | 47
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 44 | 44
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 41 | 41
http://identifiers.org/panther... 38 | 38
http://identifiers.org/panther... 37 | 37
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 33 | 33
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 31 | 31
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http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 27 | 27
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 17 | 17
http://identifiers.org/panther... 16 | 16
http://identifiers.org/panther... 15 | 15
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 13 | 13
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 8 | 8
http://identifiers.org/panther... 8 | 8

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adenylate cyclase type 10 ADCY10 Tchem Enzyme -3.13751 1324.4 108
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 GNG8 Tdark Non-IDG -2.17483 154.8 34
Metabotropic glutamate receptor 7 GRM7 Tchem GPCR -2.25415 190.8 304
Metabotropic glutamate receptor 4 GRM4 Tchem GPCR -2.34335 217.2 150
cAMP-dependent protein kinase catalytic subunit PRKX PRKX Tchem Kinase -1.17196 28.7 183
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 GNG10 Tdark Non-IDG 0.16 0.62 18
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 GNG5 Tbio Non-IDG -0.57807 4.05 87
Metabotropic glutamate receptor 5 GRM5 Tchem GPCR -3.12353 1370.3 396
Excitatory amino acid transporter 4 SLC1A6 Tchem Transporter -1.89314 75.8 107
Voltage-dependent N-type calcium channel subunit alpha-1B CACNA1B Tclin Ion Channel -2.24422 170.7 75