Development Level

Tbio 15 | 11,445
Tclin 15 | 613
Tchem 10 | 1,598
Tdark 2 | 6,588

Collection

Ion Channel: IDG Consortium (T... 2 | 99

IMPC Phenotype

preweaning lethality, complete... 5 | 979
preweaning lethality, incomple... 3 | 499
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal epididymis morphology 1 | 42
decreased body weight 1 | 161
decreased circulating chloride... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased heart weight 1 | 27
decreased total body fat amoun... 1 | 207
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating choleste... 1 | 66
increased circulating iron lev... 1 | 30
increased circulating triglyce... 1 | 42
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 36
increased startle reflex 1 | 112
microphthalmia 1 | 26

Disease

Carcinoma 36 | 11,493
Schizophrenia 33 | 1,160
glioblastoma 31 | 5,792
atypical teratoid / rhabdoid tumor 29 | 5,112
ependymoma 29 | 4,679
medulloblastoma, large-cell 29 | 6,241
Astrocytoma, Pilocytic 26 | 3,081
Bipolar Disorder 26 | 666
adult high grade glioma 24 | 3,801
primitive neuroectodermal tumor 22 | 3,035
group 3 medulloblastoma 21 | 4,104
oligodendroglioma 21 | 2,850
astrocytic glioma 19 | 2,597
lung carcinoma 18 | 2,843
osteosarcoma 18 | 7,950
psoriasis 18 | 6,694
Kidney cancer 17 | 2,613
Epilepsy 16 | 792
ovarian cancer 16 | 8,520
subependymal giant cell astrocytoma 14 | 2,287
Parkinson's disease 13 | 392
Intellectual disability 11 | 1,016
Lennox-Gastaut syndrome 11 | 34
Major Depressive Disorder 11 | 301
Pick disease 11 | 1,894
Simple partial seizure 11 | 26
Toxic encephalopathy 11 | 141
General anesthesia 10 | 53
Local anesthesia 10 | 40
lung cancer 10 | 4,740
Alcoholic Intoxication, Chronic 9 | 289
Depressive disorder 9 | 409
Epilepsy characterized by intractable complex partial seizures 9 | 28
Mental Depression 9 | 333
Migraine Prevention 9 | 23
Tonic-clonic epilepsy 9 | 47
Autistic Disorder 8 | 364
malignant mesothelioma 8 | 3,232
Alzheimer's disease 7 | 658
Amyotrophic lateral sclerosis 7 | 451
Melanoma 7 | 711
Tetanus 7 | 68
Unipolar Depression 7 | 250
Alcoholism 6 | 45
Arteriosclerotic Parkinsonism 6 | 8
Cocaine-Related Disorders 6 | 92
Extrapyramidal disease 6 | 8
Influenza A Prevention 6 | 7
Influenza due to Influenza A virus 6 | 7
Liver cancer 6 | 604
Parkinsonism 6 | 18
Postencephalitic parkinsonism 6 | 12
Psychotic Disorders 6 | 151
Skin cancer 6 | 469
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
non primary Sjogren syndrome sicca 6 | 891
pediatric high grade glioma 6 | 1,064
pituitary cancer 6 | 1,972
Dull intelligence 5 | 645
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Mood Disorders 5 | 184
Poor school performance 5 | 645
Seizures 5 | 596
astrocytoma 5 | 1,146
group 4 medulloblastoma 5 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
invasive ductal carcinoma 5 | 2,951
lung adenocarcinoma 5 | 2,716
Alcohol dependence 4 | 107
Attention deficit hyperactivity disorder 4 | 278
Botulism 4 | 24
Breast cancer 4 | 3,578
Cognitive delay 4 | 608
Global developmental delay 4 | 608
Huntington's disease 4 | 76
Mental and motor retardation 4 | 608
Moderate to Severe Alzheimer's Type Dementia 4 | 5
Partial seizure 4 | 15
Rheumatoid arthritis 4 | 1,191
Vascular disease 4 | 319
cystic fibrosis 4 | 1,696
ductal carcinoma in situ 4 | 1,745
pancreatic cancer 4 | 2,398
Autosomal recessive predisposition 3 | 1,442
Brain Ischemia 3 | 110
Cerebrovascular disease 3 | 238
Down syndrome 3 | 499
Morphine dependence 3 | 16
Multiple myeloma 3 | 1,332
acute quadriplegic myopathy 3 | 1,158
adrenocortical carcinoma 3 | 1,428
fibroadenoma 3 | 559
gastric carcinoma 3 | 807
interstitial cystitis 3 | 2,312
juvenile dermatomyositis 3 | 1,187
non-small cell lung cancer 3 | 2,890
primary pancreatic ductal adenocarcinoma 3 | 1,109

Tissue

Endocrine System 41 | 18,159
Nervous System 41 | 16,725
Blood and immune system 39 | 16,909
Digestive Tract 39 | 17,369
Female tissues 38 | 17,400
Skin and soft tissues 38 | 17,230
Urinary Tract 37 | 16,678
Liver and Pancreas 36 | 16,750
Male tissues 36 | 17,142
Respiratory system 33 | 16,393
Cardiovascular System 28 | 15,192

Target Family

Ion Channel 17 | 344
Non-IDG 12 | 12,091
Transporter 7 | 473
Kinase 3 | 634
GPCR 2 | 408
Enzyme 1 | 4,145

PathwayCommons: panther Pathway

http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 264 | 264
http://identifiers.org/panther... 197 | 197
http://identifiers.org/panther... 164 | 164
http://identifiers.org/panther... 151 | 151
http://identifiers.org/panther... 150 | 150
http://identifiers.org/panther... 149 | 149
http://identifiers.org/panther... 146 | 146
http://identifiers.org/panther... 124 | 124
http://identifiers.org/panther... 118 | 118
http://identifiers.org/panther... 116 | 116
http://identifiers.org/panther... 115 | 115
http://identifiers.org/panther... 110 | 110
http://identifiers.org/panther... 107 | 107
http://identifiers.org/panther... 104 | 104
http://identifiers.org/panther... 91 | 91
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 86 | 86
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 67 | 67
http://identifiers.org/panther... 65 | 65
http://identifiers.org/panther... 63 | 63
http://identifiers.org/panther... 61 | 61
http://identifiers.org/panther... 60 | 60
http://identifiers.org/panther... 56 | 56
http://identifiers.org/panther... 54 | 54
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 51 | 51
http://identifiers.org/panther... 47 | 47
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 44 | 44
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 41 | 41
http://identifiers.org/panther... 38 | 38
http://identifiers.org/panther... 37 | 37
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 33 | 33
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 31 | 31
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 27 | 27
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 17 | 17
http://identifiers.org/panther... 16 | 16
http://identifiers.org/panther... 15 | 15
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 13 | 13
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 8 | 8
http://identifiers.org/panther... 8 | 8

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Metabotropic glutamate receptor 3 GRM3 Tchem GPCR -2.30964 186.9 274
Calcium/calmodulin-dependent protein kinase type II subunit beta CAMK2B Tchem Kinase -1.14550 13.6 344
Excitatory amino acid transporter 4 SLC1A6 Tchem Transporter -1.89314 75.8 107
Calcium/calmodulin-dependent protein kinase type II subunit alpha CAMK2A Tchem Kinase -1.82317 50.9 620
Vesicular glutamate transporter 2 SLC17A6 Tbio Transporter -2.57663 372.2 154
Glutamate receptor ionotropic, kainate 4 GRIK4 Tclin Ion Channel -2.19499 147.3 105
Vesicle-fusing ATPase NSF Tbio Enzyme -2.93271 688.8 206
Vesicle-associated membrane protein 1 VAMP1 Tbio Non-IDG -1.75853 52.6 249
Excitatory amino acid transporter 5 SLC1A7 Tchem Transporter -1.73005 48.2 83
Excitatory amino acid transporter 1 SLC1A3 Tchem Transporter -2.76402 569.7 221