Development Level

Tbio 14 | 11,445
Tchem 12 | 1,598
Tclin 2 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

increased erythrocyte cell num... 2 | 39
increased neutrophil cell numb... 2 | 46
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal digit morphology 1 | 10
abnormal eye size 1 | 7
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal lung morphology 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal social-conspecific in... 1 | 3
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
impaired righting response 1 | 26
increased hematocrit 1 | 46
increased lymphocyte cell numb... 1 | 32
increased monocyte cell number 1 | 63
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 19 | 11,493
ovarian cancer 19 | 8,520
osteosarcoma 18 | 7,950
Cancer 16 | 2,499
glioblastoma 16 | 5,792
atypical teratoid / rhabdoid tumor 15 | 5,112
lung cancer 15 | 4,740
medulloblastoma, large-cell 15 | 6,241
adult high grade glioma 13 | 3,801
ependymoma 11 | 4,679
Astrocytoma, Pilocytic 10 | 3,081
psoriasis 10 | 6,694
Breast cancer 9 | 3,578
tuberculosis 9 | 2,010
Arthritis 8 | 290
malignant mesothelioma 8 | 3,232
Schizophrenia 7 | 1,160
Vascular disease 7 | 319
subependymal giant cell astrocytoma 7 | 2,287
Rheumatoid arthritis 6 | 1,191
group 3 medulloblastoma 6 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
invasive ductal carcinoma 6 | 2,951
juvenile dermatomyositis 6 | 1,187
non-small cell lung cancer 6 | 2,890
Asthma 5 | 385
Disease Models, Animal 5 | 155
Lung disease 5 | 142
Multiple Sclerosis 5 | 540
group 4 medulloblastoma 5 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
pituitary cancer 5 | 1,972
primitive neuroectodermal tumor 5 | 3,035
Alzheimer's disease 4 | 658
Brain Ischemia 4 | 110
Cardiomyopathies 4 | 110
Cholestasis, Extrahepatic 4 | 25
Hyperalgesia 4 | 83
Inflammatory bowel disease 4 | 151
Liver Cirrhosis, Experimental 4 | 769
Lung Neoplasms 4 | 232
Myocardial Ischemia 4 | 169
Neoplasm Metastasis 4 | 168
Obesity 4 | 678
Precancerous Conditions 4 | 80
Trigeminal Neuralgia 4 | 24
astrocytic glioma 4 | 2,597
breast carcinoma 4 | 1,638
cystic fibrosis 4 | 1,696
diabetes mellitus 4 | 1,728
interstitial cystitis 4 | 2,312
lung adenocarcinoma 4 | 2,716
lung carcinoma 4 | 2,843
pancreatic cancer 4 | 2,398
pancreatic carcinoma 4 | 562
primary Sjogren syndrome 4 | 735
Anemia 3 | 365
Autosomal recessive predisposition 3 | 1,442
Bipolar Disorder 3 | 666
Crohn's disease 3 | 321
Dermatitis, Allergic Contact 3 | 67
Heart disease 3 | 306
Hepatitis C 3 | 94
Hyperglycemia 3 | 137
Kidney cancer 3 | 2,613
Kidney disease 3 | 430
Liver Neoplasms, Experimental 3 | 59
Liver disease 3 | 237
MYCOBACTERIUM TUBERCULOSIS, SUSCEPTIBILITY TO 3 | 11
MYCOBACTERIUM TUBERCULOSIS, SUSCEPTIBILITY TO (finding) 3 | 11
Mental Depression 3 | 333
Multiple myeloma 3 | 1,332
Mycobacterium Infections, Nontuberculous 3 | 5
Nerve Degeneration 3 | 121
Radiation Injuries, Experimental 3 | 11
Recurrent mycobacterial infections 3 | 7
Sepsis 3 | 24
Stomach Neoplasms 3 | 300
adrenocortical carcinoma 3 | 1,428
esophageal adenocarcinoma 3 | 737
spina bifida 3 | 1,074
ulcerative colitis 3 | 1,819
Atherosclerosis 2 | 291
Atopic dermatitis 2 | 952
Carcinoma, Hepatocellular 2 | 228
Cholestasis 2 | 155
Dermatitis 2 | 157
Dermatitis, Atopic 2 | 37
Eye disease 2 | 62
Hypereosinophilic syndrome 2 | 71
Hypersensitivity reaction type II disease 2 | 253
Liver carcinoma 2 | 240
Malaria 2 | 160
Parkinson's disease 2 | 392
Reperfusion Injury 2 | 86
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
head and neck cancer 2 | 271

Tissue

Blood and immune system 28 | 16,909
Cardiovascular System 28 | 15,192
Digestive Tract 28 | 17,369
Endocrine System 28 | 18,159
Female tissues 28 | 17,400
Liver and Pancreas 28 | 16,750
Male tissues 28 | 17,142
Nervous System 28 | 16,725
Respiratory system 28 | 16,393
Skin and soft tissues 28 | 17,230
Urinary Tract 28 | 16,678

Target Family

Kinase 12 | 634
Non-IDG 10 | 12,091
Transcription Factor 5 | 1,400
Enzyme 1 | 4,145

PathwayCommons: panther Pathway

http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 264 | 264
http://identifiers.org/panther... 197 | 197
http://identifiers.org/panther... 164 | 164
http://identifiers.org/panther... 151 | 151
http://identifiers.org/panther... 150 | 150
http://identifiers.org/panther... 149 | 149
http://identifiers.org/panther... 146 | 146
http://identifiers.org/panther... 124 | 124
http://identifiers.org/panther... 118 | 118
http://identifiers.org/panther... 116 | 116
http://identifiers.org/panther... 115 | 115
http://identifiers.org/panther... 110 | 110
http://identifiers.org/panther... 107 | 107
http://identifiers.org/panther... 104 | 104
http://identifiers.org/panther... 91 | 91
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 86 | 86
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 67 | 67
http://identifiers.org/panther... 65 | 65
http://identifiers.org/panther... 63 | 63
http://identifiers.org/panther... 61 | 61
http://identifiers.org/panther... 60 | 60
http://identifiers.org/panther... 56 | 56
http://identifiers.org/panther... 54 | 54
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 51 | 51
http://identifiers.org/panther... 47 | 47
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 44 | 44
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 41 | 41
http://identifiers.org/panther... 38 | 38
http://identifiers.org/panther... 37 | 37
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 33 | 33
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 31 | 31
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 27 | 27
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 17 | 17
http://identifiers.org/panther... 16 | 16
http://identifiers.org/panther... 15 | 15
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 13 | 13
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 8 | 8
http://identifiers.org/panther... 8 | 8

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Suppressor of cytokine signaling 4 SOCS4 Tbio Non-IDG -1.22763 14.8 224
E3 SUMO-protein ligase PIAS3 PIAS3 Tbio Transcription Factor -1.74449 53.4 174
Suppressor of cytokine signaling 5 SOCS5 Tbio Non-IDG -2.04740 106.6 135
Suppressor of cytokine signaling 7 SOCS7 Tbio Non-IDG -1.64336 42.5 122
E3 SUMO-protein ligase PIAS1 PIAS1 Tbio Transcription Factor -1.86330 76.2 272
E3 SUMO-protein ligase PIAS2 PIAS2 Tbio Transcription Factor -1.84354 65.2 389
Mitogen-activated protein kinase 10 MAPK10 Tchem Kinase -2.29568 193.3 384
Mitogen-activated protein kinase 12 MAPK12 Tchem Kinase -1.95173 88.4 378
Interferon gamma receptor 2 IFNGR2 Tbio Non-IDG -1.70048 44.2 264
Mitogen-activated protein kinase 1 MAPK1 Tchem Kinase -3.18822 1239.4 1248