Development Level

Tbio 103 | 11,445
Tchem 74 | 1,598
Tclin 14 | 613
Tdark 6 | 6,588

Collection

Kinase: IDG Consortium (Target... 5 | 125

IMPC Phenotype

preweaning lethality, complete... 9 | 979
preweaning lethality, incomple... 9 | 499
decreased body weight 4 | 161
embryonic lethality prior to t... 4 | 278
abnormal behavior 3 | 298
abnormal behavioral response t... 3 | 66
abnormal bone structure 3 | 187
decreased bone mineral content 3 | 151
decreased circulating insulin ... 3 | 76
decreased circulating triglyce... 3 | 79
decreased hematocrit 3 | 46
embryonic growth retardation 3 | 106
improved glucose tolerance 3 | 79
increased circulating alkaline... 3 | 122
increased erythrocyte cell num... 3 | 39
increased lean body mass 3 | 172
increased neutrophil cell numb... 3 | 46
increased or absent threshold ... 3 | 101
increased total body fat amoun... 3 | 134
short tibia 3 | 97
abnormal bone mineralization 2 | 38
abnormal gait 2 | 69
abnormal retina morphology 2 | 71
abnormal seminal vesicle morph... 2 | 114
abnormal vocalization 2 | 21
convulsive seizures 2 | 13
decreased bone mineral density 2 | 126
decreased circulating choleste... 2 | 93
decreased circulating creatini... 2 | 39
decreased circulating fructosa... 2 | 30
decreased circulating iron lev... 2 | 32
decreased circulating serum al... 2 | 82
decreased circulating total pr... 2 | 49
decreased erythrocyte cell num... 2 | 62
decreased grip strength 2 | 116
decreased hemoglobin content 2 | 68
decreased leukocyte cell numbe... 2 | 73
decreased lymphocyte cell numb... 2 | 83
decreased prepulse inhibition 2 | 82
decreased startle reflex 2 | 75
decreased total body fat amoun... 2 | 207
edema 2 | 59
embryonic lethality prior to o... 2 | 239
hydrometra 2 | 53
increased circulating calcium ... 2 | 34
increased circulating creatini... 2 | 38
increased circulating triglyce... 2 | 42
increased hemoglobin content 2 | 45
increased monocyte cell number 2 | 63
prenatal lethality prior to he... 2 | 87
small superior vagus ganglion 2 | 74
vertebral fusion 2 | 23
abnormal coat-hair pigmentatio... 1 | 64
abnormal colon morphology 1 | 3
abnormal cranium morphology 1 | 36
abnormal lens morphology 1 | 81
abnormal locomotor behavior 1 | 24
abnormal lung morphology 1 | 26
abnormal pericardium morpholog... 1 | 26
abnormal skin coloration 1 | 25
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased anxiety-related resp... 1 | 12
decreased body length 1 | 101
decreased circulating amylase ... 1 | 28
decreased circulating phosphat... 1 | 27
decreased exploration in new e... 1 | 11
decreased fasted circulating g... 1 | 65
decreased heart left ventricle... 1 | 28
decreased heart rate 1 | 18
decreased lean body mass 1 | 135
decreased mean platelet volume 1 | 25
decreased neutrophil cell numb... 1 | 42
hemorrhage 1 | 23
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased bone mineral content 1 | 108
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating choleste... 1 | 66
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating magnesiu... 1 | 10
increased circulating total pr... 1 | 28
increased fasted circulating g... 1 | 76
increased heart rate variabili... 1 | 7
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular vol... 1 | 92
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
prenatal lethality 1 | 28
prolonged RR interval 1 | 8
thrombocytosis 1 | 27

Disease

Carcinoma 135 | 11,493
ovarian cancer 112 | 8,520
psoriasis 104 | 6,694
osteosarcoma 103 | 7,950
glioblastoma 95 | 5,792
Cancer 85 | 2,499
lung cancer 79 | 4,740
medulloblastoma, large-cell 79 | 6,241
atypical teratoid / rhabdoid tumor 73 | 5,112
ependymoma 67 | 4,679
lung carcinoma 66 | 2,843
Astrocytoma, Pilocytic 62 | 3,081
adult high grade glioma 62 | 3,801
Breast cancer 59 | 3,578
malignant mesothelioma 54 | 3,232
ulcerative colitis 54 | 1,819
Kidney cancer 53 | 2,613
interstitial cystitis 53 | 2,312
pancreatic cancer 50 | 2,398
invasive ductal carcinoma 47 | 2,951
tuberculosis 47 | 2,010
group 3 medulloblastoma 44 | 4,104
primitive neuroectodermal tumor 44 | 3,035
lung adenocarcinoma 43 | 2,716
intraductal papillary-mucinous carcinoma (IPMC) 42 | 2,989
non-small cell lung cancer 41 | 2,890
subependymal giant cell astrocytoma 41 | 2,287
Asthma 39 | 385
intraductal papillary-mucinous adenoma (IPMA) 39 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 38 | 3,291
cutaneous lupus erythematosus 34 | 1,057
diabetes mellitus 34 | 1,728
Rheumatoid arthritis 33 | 1,191
oligodendroglioma 32 | 2,850
breast carcinoma 29 | 1,638
colon cancer 29 | 1,478
group 4 medulloblastoma 29 | 1,855
Melanoma 28 | 711
Schizophrenia 28 | 1,160
astrocytic glioma 28 | 2,597
juvenile dermatomyositis 28 | 1,187
Arthritis 27 | 290
Multiple Sclerosis 27 | 540
cystic fibrosis 27 | 1,696
pituitary cancer 26 | 1,972
Autosomal recessive predisposition 25 | 1,442
Liver Cirrhosis, Experimental 25 | 769
primary pancreatic ductal adenocarcinoma 25 | 1,109
Pick disease 23 | 1,894
astrocytoma 23 | 1,146
Breast Neoplasms 22 | 445
Liver cancer 22 | 604
nasopharyngeal carcinoma 22 | 1,058
primary Sjogren syndrome 22 | 735
Mammary Neoplasms 21 | 425
Skin cancer 21 | 469
Hypersensitivity reaction type II disease 20 | 253
pediatric high grade glioma 20 | 1,064
Bipolar Disorder 19 | 666
Kidney disease 19 | 430
Lung disease 19 | 142
Vascular disease 19 | 319
Byzanthine arch palate 18 | 194
Multiple myeloma 18 | 1,332
Pneumonia 18 | 174
Prostatic Neoplasms 18 | 495
acute quadriplegic myopathy 18 | 1,158
Atherosclerosis 17 | 291
Hypersensitivity 17 | 63
Hypertension 17 | 396
Obesity 17 | 678
Waldenstrons macroglobulinemia 17 | 765
ductal carcinoma in situ 17 | 1,745
pancreatic carcinoma 17 | 562
pancreatic ductal adenocarcinoma liver metastasis 17 | 1,962
Duchenne muscular dystrophy 16 | 601
Epilepsy 16 | 792
Human immunodeficiency virus infectious disease 16 | 138
Hypertensive disease 16 | 292
Inflammatory bowel disease 16 | 151
adrenocortical carcinoma 16 | 1,428
Acquired scoliosis 15 | 281
Atopic dermatitis 15 | 952
Coronary artery disease 15 | 268
Curvature of spine 15 | 282
Dermatitis 15 | 157
Heart disease 15 | 306
Intellectual disability 15 | 1,016
Lung Neoplasms 15 | 232
Seizures 15 | 596
hepatocellular carcinoma 15 | 547
Crohn's disease 14 | 321
Down syndrome 14 | 499
Stomach Neoplasms 14 | 300
sarcoidosis 14 | 370
Dull intelligence 13 | 645
Mental deficiency 13 | 645
Poor school performance 13 | 645
gastric cancer 13 | 459
periodontitis 13 | 293

Tissue

Endocrine System 196 | 18,159
Skin and soft tissues 195 | 17,230
Digestive Tract 193 | 17,369
Female tissues 192 | 17,400
Male tissues 192 | 17,142
Blood and immune system 190 | 16,909
Liver and Pancreas 190 | 16,750
Urinary Tract 187 | 16,678
Nervous System 184 | 16,725
Respiratory system 184 | 16,393
Cardiovascular System 180 | 15,192

Target Family

Non-IDG 89 | 12,091
Kinase 39 | 634
Enzyme 31 | 4,145
GPCR 23 | 408
Transcription Factor 12 | 1,400
Ion Channel 3 | 344

PathwayCommons: panther Pathway

http://identifiers.org/panther... 197 | 197
http://identifiers.org/panther... 264 | 264
http://identifiers.org/panther... 164 | 164
http://identifiers.org/panther... 151 | 151
http://identifiers.org/panther... 150 | 150
http://identifiers.org/panther... 149 | 149
http://identifiers.org/panther... 146 | 146
http://identifiers.org/panther... 124 | 124
http://identifiers.org/panther... 118 | 118
http://identifiers.org/panther... 116 | 116
http://identifiers.org/panther... 115 | 115
http://identifiers.org/panther... 110 | 110
http://identifiers.org/panther... 107 | 107
http://identifiers.org/panther... 104 | 104
http://identifiers.org/panther... 91 | 91
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 86 | 86
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 67 | 67
http://identifiers.org/panther... 65 | 65
http://identifiers.org/panther... 63 | 63
http://identifiers.org/panther... 61 | 61
http://identifiers.org/panther... 60 | 60
http://identifiers.org/panther... 56 | 56
http://identifiers.org/panther... 54 | 54
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 51 | 51
http://identifiers.org/panther... 47 | 47
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 44 | 44
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 41 | 41
http://identifiers.org/panther... 38 | 38
http://identifiers.org/panther... 37 | 37
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 33 | 33
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 31 | 31
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 27 | 27
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 17 | 17
http://identifiers.org/panther... 16 | 16
http://identifiers.org/panther... 15 | 15
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 13 | 13
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 8 | 8
http://identifiers.org/panther... 8 | 8

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Suppressor of cytokine signaling 4 SOCS4 Tbio Non-IDG -1.22763 14.8 224
Myosin-13 MYH13 Tbio Non-IDG -1.26079 16.6 12
Myosin-2 MYH2 Tbio Non-IDG -2.14128 114.9 63
Myosin-4 MYH4 Tbio Non-IDG -1.81214 51.8 52
C-C motif chemokine 3-like 1 CCL3L1 Tbio Non-IDG -1.80717 51.3 142
Guanine nucleotide-binding protein subunit alpha-11 GNA11 Tbio Non-IDG -2.80484 555.1 184
Nuclear factor of activated T-cells, cytoplasmic 4 NFATC4 Tbio Transcription Factor -1.93766 88.3 358
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 GNG8 Tdark Non-IDG -2.17483 154.8 34
Myosin-IIIb MYO3B Tbio Kinase -0.73450 5.14 127
Collagen alpha-1(XII) chain COL12A1 Tbio Non-IDG -1.36571 21.4 38