Development Level

Tbio 69 | 11,445
Tchem 20 | 1,598
Tclin 20 | 613
Tdark 7 | 6,588

Collection

Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 8 | 979
preweaning lethality, incomple... 5 | 499
decreased body weight 4 | 161
abnormal lens morphology 3 | 81
decreased bone mineral content 3 | 151
decreased circulating LDL chol... 3 | 38
decreased circulating choleste... 3 | 93
embryonic lethality prior to t... 3 | 278
abnormal bone mineralization 2 | 38
abnormal bone structure 2 | 187
abnormal retina morphology 2 | 71
cataract 2 | 92
decreased body length 2 | 101
decreased circulating HDL chol... 2 | 68
decreased circulating potassiu... 2 | 20
decreased circulating serum al... 2 | 82
decreased circulating sodium l... 2 | 22
decreased circulating triglyce... 2 | 79
decreased grip strength 2 | 116
decreased total body fat amoun... 2 | 207
embryonic growth retardation 2 | 106
increased circulating alkaline... 2 | 122
increased circulating chloride... 2 | 41
increased circulating choleste... 2 | 66
increased lean body mass 2 | 172
increased startle reflex 2 | 112
short tibia 2 | 97
tremors 2 | 39
abnormal behavior 1 | 298
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal glucose homeostasis 1 | 4
abnormal lung morphology 1 | 26
abnormal rib morphology 1 | 10
abnormal seminal vesicle morph... 1 | 114
absent pinna reflex 1 | 23
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating creatini... 1 | 39
decreased circulating fructosa... 1 | 30
decreased exploration in new e... 1 | 11
decreased heart left ventricle... 1 | 28
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased mean corpuscular vol... 1 | 79
decreased monocyte cell number 1 | 8
decreased neutrophil cell numb... 1 | 42
decreased spleen weight 1 | 10
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
enlarged kidney 1 | 14
enlarged lymph nodes 1 | 37
fusion of vertebral arches 1 | 7
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating creatini... 1 | 38
increased circulating free fat... 1 | 20
increased circulating glucose ... 1 | 24
increased circulating potassiu... 1 | 29
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular vol... 1 | 92
increased neutrophil cell numb... 1 | 46
increased red blood cell distr... 1 | 34
increased spleen weight 1 | 10
increased total body fat amoun... 1 | 134
long tibia 1 | 25
microphthalmia 1 | 26
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
prolonged PR interval 1 | 15
thin ventricular wall 1 | 24
thrombocytosis 1 | 27
vertebral fusion 1 | 23

Disease

Carcinoma 85 | 11,493
ovarian cancer 70 | 8,520
osteosarcoma 56 | 7,950
glioblastoma 53 | 5,792
psoriasis 49 | 6,694
medulloblastoma, large-cell 46 | 6,241
atypical teratoid / rhabdoid tumor 44 | 5,112
ependymoma 43 | 4,679
adult high grade glioma 37 | 3,801
Breast cancer 35 | 3,578
lung cancer 35 | 4,740
Astrocytoma, Pilocytic 31 | 3,081
Cancer 30 | 2,499
Kidney cancer 30 | 2,613
astrocytic glioma 30 | 2,597
group 3 medulloblastoma 29 | 4,104
oligodendroglioma 29 | 2,850
Schizophrenia 28 | 1,160
malignant mesothelioma 28 | 3,232
primitive neuroectodermal tumor 27 | 3,035
subependymal giant cell astrocytoma 27 | 2,287
pancreatic cancer 25 | 2,398
intraductal papillary-mucinous neoplasm (IPMN) 24 | 3,291
Epilepsy 23 | 792
Intellectual disability 22 | 1,016
intraductal papillary-mucinous adenoma (IPMA) 22 | 2,955
Bipolar Disorder 21 | 666
Pick disease 21 | 1,894
non-small cell lung cancer 21 | 2,890
diabetes mellitus 20 | 1,728
Multiple myeloma 19 | 1,332
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,989
lung carcinoma 19 | 2,843
Seizures 18 | 596
Melanoma 17 | 711
breast carcinoma 17 | 1,638
juvenile dermatomyositis 17 | 1,187
lung adenocarcinoma 17 | 2,716
Parkinson's disease 16 | 392
Toxic encephalopathy 16 | 141
acute quadriplegic myopathy 15 | 1,158
group 4 medulloblastoma 15 | 1,855
pituitary cancer 15 | 1,972
Huntington's disease 14 | 76
Skin cancer 14 | 469
astrocytoma 14 | 1,146
primary pancreatic ductal adenocarcinoma 14 | 1,109
Breast Neoplasms 13 | 445
Dull intelligence 13 | 645
Low intelligence 13 | 645
Mental Retardation 13 | 645
Mental deficiency 13 | 645
Neurodegenerative disease 13 | 414
Poor school performance 13 | 645
Waldenstrons macroglobulinemia 13 | 765
colon cancer 13 | 1,478
invasive ductal carcinoma 13 | 2,951
Alzheimer's disease 12 | 658
Amyotrophic lateral sclerosis 12 | 451
Depressive disorder 12 | 409
Endometrial cancer 12 | 311
Liver cancer 12 | 604
Autosomal recessive predisposition 11 | 1,442
Duchenne muscular dystrophy 11 | 601
Mammary Neoplasms 11 | 425
Rheumatoid arthritis 11 | 1,191
cystic fibrosis 11 | 1,696
nasopharyngeal carcinoma 11 | 1,058
Liposarcoma 10 | 20
Lung Neoplasms 10 | 232
Malignant tumor of prostate 10 | 26
Nephroblastoma 10 | 51
Ocular hypertension 10 | 42
Vascular disease 10 | 319
hepatocellular carcinoma 10 | 547
non primary Sjogren syndrome sicca 10 | 891
spina bifida 10 | 1,074
tuberculosis 10 | 2,010
Alcoholic Intoxication, Chronic 9 | 289
Autistic Disorder 9 | 364
Gestational trophoblastic neoplasia 9 | 14
HER2-positive carcinoma of breast 9 | 21
Hodgkin's disease 9 | 18
Kaposi's sarcoma 9 | 22
Liver Cirrhosis, Experimental 9 | 769
Malignant tumor of head and/or neck 9 | 15
Malignant tumor of ovary 9 | 25
Mental Depression 9 | 333
Metastatic Prostate Carcinoma 9 | 18
Neuroblastoma 9 | 80
Open-angle glaucoma 9 | 27
Rhabdomyosarcoma 9 | 39
Secondary malignant neoplasm of pancreas 9 | 10
adrenocortical carcinoma 9 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 9 | 510
ductal carcinoma in situ 9 | 1,745
interstitial cystitis 9 | 2,312
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
transitional cell carcinoma 9 | 22
ulcerative colitis 9 | 1,819

Tissue

Endocrine System 116 | 18,159
Digestive Tract 115 | 17,369
Female tissues 115 | 17,400
Skin and soft tissues 115 | 17,230
Blood and immune system 113 | 16,909
Respiratory system 113 | 16,393
Urinary Tract 112 | 16,678
Male tissues 111 | 17,142
Nervous System 111 | 16,725
Liver and Pancreas 110 | 16,750
Cardiovascular System 103 | 15,192

Target Family

Non-IDG 67 | 12,091
Enzyme 22 | 4,145
Ion Channel 11 | 344
Kinase 8 | 634
Transcription Factor 6 | 1,400
Epigenetic 2 | 242

PathwayCommons: panther Pathway

http://identifiers.org/panther... 116 | 116
http://identifiers.org/panther... 264 | 264
http://identifiers.org/panther... 197 | 197
http://identifiers.org/panther... 164 | 164
http://identifiers.org/panther... 151 | 151
http://identifiers.org/panther... 150 | 150
http://identifiers.org/panther... 149 | 149
http://identifiers.org/panther... 146 | 146
http://identifiers.org/panther... 124 | 124
http://identifiers.org/panther... 118 | 118
http://identifiers.org/panther... 115 | 115
http://identifiers.org/panther... 110 | 110
http://identifiers.org/panther... 107 | 107
http://identifiers.org/panther... 104 | 104
http://identifiers.org/panther... 91 | 91
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 86 | 86
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 67 | 67
http://identifiers.org/panther... 65 | 65
http://identifiers.org/panther... 63 | 63
http://identifiers.org/panther... 61 | 61
http://identifiers.org/panther... 60 | 60
http://identifiers.org/panther... 56 | 56
http://identifiers.org/panther... 54 | 54
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 51 | 51
http://identifiers.org/panther... 47 | 47
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 44 | 44
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 41 | 41
http://identifiers.org/panther... 38 | 38
http://identifiers.org/panther... 37 | 37
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 33 | 33
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 31 | 31
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 27 | 27
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 17 | 17
http://identifiers.org/panther... 16 | 16
http://identifiers.org/panther... 15 | 15
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 13 | 13
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 8 | 8
http://identifiers.org/panther... 8 | 8

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Huntingtin HTT Tchem Non-IDG -3.36282 2294.8 599
Tubulin beta-6 chain TUBB6 Tclin Non-IDG -0.94163 8.01 85
Tubulin beta-4A chain TUBB4A Tclin Non-IDG -2.98371 896.1 90
Mitogen-activated protein kinase kinase kinase 10 MAP3K10 Tchem Kinase -1.20048 15.1 221
Calpain-10 CAPN10 Tbio Non-IDG -2.27096 197.8 112
Calpain-12 CAPN12 Tdark Non-IDG -0.45780 3.51 74
ADP-ribosylation factor 3 ARF3 Tbio Enzyme -2.38391 168.3 82
Cytoplasmic dynein 2 heavy chain 1 DYNC2H1 Tbio Non-IDG -1.60757 39.5 23
Actin, gamma-enteric smooth muscle ACTG2 Tbio Non-IDG -1.98240 92.4 212
Actin, cytoplasmic 2 ACTG1 Tbio Non-IDG -2.50312 297.3 225