Development Level

Tbio 60 | 11,445
Tchem 43 | 1,598
Tclin 42 | 613
Tdark 4 | 6,588

Collection

GPCR: IDG Consortium (Targets) 4 | 126
Kinase: IDG Consortium (Target... 4 | 125
GPCR: IDG Consortium (Complete... 2 | 25

IMPC Phenotype

decreased total body fat amoun... 5 | 207
preweaning lethality, incomple... 5 | 499
hyperactivity 4 | 148
abnormal behavior 3 | 298
decreased vertical activity 3 | 208
increased circulating sodium l... 3 | 71
increased total body fat amoun... 3 | 134
abnormal behavioral response t... 2 | 66
cataract 2 | 92
decreased body weight 2 | 161
decreased circulating glucose ... 2 | 126
decreased circulating glycerol... 2 | 16
decreased lean body mass 2 | 135
impaired pupillary reflex 2 | 26
increased circulating chloride... 2 | 41
increased circulating triglyce... 2 | 42
increased fasted circulating g... 2 | 76
increased lean body mass 2 | 172
increased mean platelet volume 2 | 45
limb grasping 2 | 41
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal retina morphology 1 | 71
abnormal spleen morphology 1 | 55
abnormal tail length 1 | 3
abnormal vibrissa morphology 1 | 25
cardiovascular system phenotyp... 1 | 36
convulsive seizures 1 | 13
decreased anxiety-related resp... 1 | 12
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased circulating chloride... 1 | 30
decreased circulating phosphat... 1 | 27
enlarged epididymis 1 | 31
enlarged heart 1 | 210
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating total pr... 1 | 28
increased erythrocyte cell num... 1 | 39
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased kidney weight 1 | 6
increased mean corpuscular vol... 1 | 92
microphthalmia 1 | 26
mydriasis 1 | 6
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 111 | 11,493
psoriasis 71 | 6,694
osteosarcoma 69 | 7,950
medulloblastoma, large-cell 67 | 6,241
glioblastoma 66 | 5,792
ovarian cancer 58 | 8,520
Schizophrenia 57 | 1,160
atypical teratoid / rhabdoid tumor 54 | 5,112
ependymoma 53 | 4,679
adult high grade glioma 50 | 3,801
group 3 medulloblastoma 44 | 4,104
oligodendroglioma 44 | 2,850
Astrocytoma, Pilocytic 43 | 3,081
astrocytic glioma 39 | 2,597
primitive neuroectodermal tumor 37 | 3,035
Bipolar Disorder 36 | 666
Depressive disorder 34 | 409
Parkinson's disease 32 | 392
Breast cancer 31 | 3,578
lung cancer 31 | 4,740
Kidney cancer 30 | 2,613
Major Depressive Disorder 29 | 301
invasive ductal carcinoma 29 | 2,951
lung carcinoma 29 | 2,843
Mood Disorders 28 | 184
malignant mesothelioma 28 | 3,232
intraductal papillary-mucinous carcinoma (IPMC) 27 | 2,989
non-small cell lung cancer 27 | 2,890
subependymal giant cell astrocytoma 26 | 2,287
Alcoholic Intoxication, Chronic 25 | 289
Mental Depression 24 | 333
diabetes mellitus 24 | 1,728
pituitary cancer 23 | 1,972
group 4 medulloblastoma 22 | 1,855
Alcohol dependence 21 | 107
Epilepsy 21 | 792
lung adenocarcinoma 21 | 2,716
pancreatic cancer 20 | 2,398
Attention deficit hyperactivity disorder 19 | 278
Pick disease 19 | 1,894
intraductal papillary-mucinous adenoma (IPMA) 19 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 19 | 3,291
Migraine 18 | 83
Unipolar Depression 18 | 250
Obesity 17 | 678
interstitial cystitis 17 | 2,312
tuberculosis 17 | 2,010
Asthma 16 | 385
Autosomal recessive predisposition 16 | 1,442
Cancer 16 | 2,499
Nasal discharge 16 | 24
astrocytoma 16 | 1,146
breast carcinoma 16 | 1,638
ulcerative colitis 16 | 1,819
Allergic rhinitis 15 | 94
Autistic Disorder 15 | 364
Hypertension 15 | 396
Nasal congestion 15 | 21
ductal carcinoma in situ 15 | 1,745
Substance Withdrawal Syndrome 14 | 55
non primary Sjogren syndrome sicca 14 | 891
Alzheimer's disease 13 | 658
Pain 13 | 103
Seizures 13 | 596
colon cancer 13 | 1,478
Bronchitis 12 | 43
Common cold 12 | 67
Hypertensive disease 12 | 292
Pulmonary emphysema 12 | 48
Rheumatoid arthritis 12 | 1,191
Substance abuse 12 | 59
Acromegaly 11 | 51
Acute exacerbation of asthma 11 | 14
Asthma management 11 | 19
Cocaine-Related Disorders 11 | 92
General anesthesia 11 | 53
Headache disorder 11 | 19
Melanoma 11 | 711
Pain agnosia 11 | 104
cystic fibrosis 11 | 1,696
Duchenne muscular dystrophy 10 | 601
Hyperactive behavior 10 | 91
Influenza-like symptoms 10 | 16
adrenocortical carcinoma 10 | 1,428
pediatric high grade glioma 10 | 1,064
Amphetamine-Related Disorders 9 | 74
Cocaine Dependence 9 | 51
Fever 9 | 138
Glycogen storage disease 9 | 39
Heart failure 9 | 162
Hypertensive disorder 9 | 56
Intellectual disability 9 | 1,016
Liver Cirrhosis, Experimental 9 | 769
Multiple myeloma 9 | 1,332
Short stature 9 | 531
Sinus headache 9 | 16
Skin cancer 9 | 469
Sneezing 9 | 12
active Crohn's disease 9 | 922
cutaneous lupus erythematosus 8 | 1,057

Tissue

Endocrine System 146 | 18,159
Nervous System 141 | 16,725
Female tissues 139 | 17,400
Skin and soft tissues 138 | 17,230
Digestive Tract 137 | 17,369
Blood and immune system 135 | 16,909
Male tissues 133 | 17,142
Liver and Pancreas 132 | 16,750
Respiratory system 128 | 16,393
Urinary Tract 128 | 16,678
Cardiovascular System 112 | 15,192

Target Family

GPCR 58 | 408
Non-IDG 40 | 12,091
Enzyme 21 | 4,145
Kinase 16 | 634
Transcription Factor 8 | 1,400
Ion Channel 4 | 344
Epigenetic 2 | 242

PathwayCommons: panther Pathway

http://identifiers.org/panther... 149 | 149
http://identifiers.org/panther... 264 | 264
http://identifiers.org/panther... 197 | 197
http://identifiers.org/panther... 164 | 164
http://identifiers.org/panther... 151 | 151
http://identifiers.org/panther... 150 | 150
http://identifiers.org/panther... 146 | 146
http://identifiers.org/panther... 124 | 124
http://identifiers.org/panther... 118 | 118
http://identifiers.org/panther... 116 | 116
http://identifiers.org/panther... 115 | 115
http://identifiers.org/panther... 110 | 110
http://identifiers.org/panther... 107 | 107
http://identifiers.org/panther... 104 | 104
http://identifiers.org/panther... 91 | 91
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 86 | 86
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 67 | 67
http://identifiers.org/panther... 65 | 65
http://identifiers.org/panther... 63 | 63
http://identifiers.org/panther... 61 | 61
http://identifiers.org/panther... 60 | 60
http://identifiers.org/panther... 56 | 56
http://identifiers.org/panther... 54 | 54
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 51 | 51
http://identifiers.org/panther... 47 | 47
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 44 | 44
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 41 | 41
http://identifiers.org/panther... 38 | 38
http://identifiers.org/panther... 37 | 37
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 33 | 33
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 31 | 31
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 27 | 27
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 17 | 17
http://identifiers.org/panther... 16 | 16
http://identifiers.org/panther... 15 | 15
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 13 | 13
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 8 | 8
http://identifiers.org/panther... 8 | 8

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adenylate cyclase type 8 ADCY8 Tbio Enzyme -2.04645 112.4 147
Somatostatin receptor type 1 SSTR1 Tclin GPCR -2.14265 126.2 303
Somatostatin receptor type 2 SSTR2 Tclin GPCR -2.53936 363.5 246
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 GNG8 Tdark Non-IDG -2.17483 154.8 34
Clathrin heavy chain 2 CLTCL1 Tbio Non-IDG -1.29555 21.3 39
5-hydroxytryptamine receptor 4 HTR4 Tclin GPCR -2.87235 796.4 248
5-hydroxytryptamine receptor 2B HTR2B Tclin GPCR -2.66641 486.3 265
Metabotropic glutamate receptor 3 GRM3 Tchem GPCR -2.30964 186.9 274
Metabotropic glutamate receptor 7 GRM7 Tchem GPCR -2.25415 190.8 304
Metabotropic glutamate receptor 4 GRM4 Tchem GPCR -2.34335 217.2 150