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Development Level

Tbio 16 | 11,445
Tchem 15 | 1,598
Tclin 6 | 613

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal retina morphology 1 | 71
abnormal retinal inner nuclear... 1 | 8
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating alkaline... 1 | 46
decreased circulating calcium ... 1 | 36
decreased leukocyte cell numbe... 1 | 73
decreased total retina thickne... 1 | 17
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
increased circulating creatini... 1 | 38
increased erythrocyte cell num... 1 | 39
increased hematocrit 1 | 46
increased mean corpuscular hem... 1 | 96
preweaning lethality, incomple... 1 | 499
small superior vagus ganglion 1 | 74

Disease

Carcinoma 29 | 11,493
Cancer 27 | 2,499
ovarian cancer 25 | 8,520
glioblastoma 23 | 5,792
lung cancer 23 | 4,740
psoriasis 21 | 6,694
atypical teratoid / rhabdoid tumor 19 | 5,112
medulloblastoma, large-cell 16 | 6,241
osteosarcoma 16 | 7,950
Breast cancer 15 | 3,578
ependymoma 15 | 4,679
group 3 medulloblastoma 15 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,291
lung carcinoma 14 | 2,843
Astrocytoma, Pilocytic 13 | 3,081
malignant mesothelioma 13 | 3,232
adult high grade glioma 12 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
subependymal giant cell astrocytoma 12 | 2,287
Kidney cancer 11 | 2,613
pancreatic cancer 11 | 2,398
interstitial cystitis 10 | 2,312
invasive ductal carcinoma 10 | 2,951
Rheumatoid arthritis 9 | 1,191
diabetes mellitus 9 | 1,728
non-small cell lung cancer 9 | 2,890
Lung Neoplasms 8 | 232
Mammary Neoplasms 8 | 425
Autosomal recessive predisposition 7 | 1,442
Breast Neoplasms 7 | 445
Melanoma 7 | 711
Pick disease 7 | 1,894
Schizophrenia 7 | 1,160
Stomach Neoplasms 7 | 300
Vascular disease 7 | 319
adrenocortical carcinoma 7 | 1,428
breast carcinoma 7 | 1,638
cutaneous lupus erythematosus 7 | 1,057
ductal carcinoma in situ 7 | 1,745
lung adenocarcinoma 7 | 2,716
pediatric high grade glioma 7 | 1,064
primitive neuroectodermal tumor 7 | 3,035
tuberculosis 7 | 2,010
Alzheimer's disease 6 | 658
Amyotrophic lateral sclerosis 6 | 451
Neurodegenerative disease 6 | 414
Prostatic Neoplasms 6 | 495
Toxic encephalopathy 6 | 141
colon cancer 6 | 1,478
pituitary cancer 6 | 1,972
ulcerative colitis 6 | 1,819
Arthritis 5 | 290
Autoimmune lymphoproliferative syndrome 5 | 11
Brain Ischemia 5 | 110
Cardiomyopathies 5 | 110
Diabetes Mellitus, Non-Insulin-Dependent 5 | 145
Disease Models, Animal 5 | 155
Endometriosis 5 | 540
Heart disease 5 | 306
Lung disease 5 | 142
Myocardial Reperfusion Injury 5 | 37
Neoplasm Metastasis 5 | 168
Obesity 5 | 678
Parkinson's disease 5 | 392
Peripheral Neuropathy 5 | 134
Reperfusion Injury 5 | 86
astrocytoma 5 | 1,146
fibroadenoma 5 | 559
group 4 medulloblastoma 5 | 1,855
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
spina bifida 5 | 1,074
Adenocarcinoma of lung 4 | 142
Asthma 4 | 385
Atherosclerosis 4 | 291
Bipolar Disorder 4 | 666
Brain disease 4 | 96
Carcinoma, Hepatocellular 4 | 228
Cardiomyopathy, Dilated 4 | 83
Colonic Neoplasms 4 | 142
Craniofacial Abnormalities 4 | 151
Diabetes Mellitus, Type 2 4 | 142
Epilepsy 4 | 792
Eye disease 4 | 62
Hepatomegaly 4 | 285
Inflammatory bowel disease 4 | 151
Liver Cirrhosis, Experimental 4 | 769
Liver Failure, Acute 4 | 29
Liver carcinoma 4 | 240
Liver disease 4 | 237
Malignant tumor of ovary 4 | 25
Neuropathy 4 | 261
Osteoporosis 4 | 363
Retinal Detachment 4 | 51
active ulcerative colitis 4 | 764
acute quadriplegic myopathy 4 | 1,158
hepatocellular carcinoma 4 | 547
nasopharyngeal carcinoma 4 | 1,058
oligodendroglioma 4 | 2,850
primary pancreatic ductal adenocarcinoma 4 | 1,109

Tissue

Blood and immune system 37 | 16,909
Cardiovascular System 37 | 15,192
Digestive Tract 37 | 17,369
Endocrine System 37 | 18,159
Female tissues 37 | 17,400
Liver and Pancreas 37 | 16,750
Male tissues 37 | 17,142
Nervous System 37 | 16,725
Respiratory system 37 | 16,393
Skin and soft tissues 37 | 17,230
Urinary Tract 37 | 16,678

Target Family

Non-IDG 14 | 12,091
Enzyme 11 | 4,145
Kinase 9 | 634
Transcription Factor 3 | 1,400

PathwayCommons: panther Pathway

http://identifiers.org/panther... 37 | 37
http://identifiers.org/panther... 264 | 264
http://identifiers.org/panther... 197 | 197
http://identifiers.org/panther... 164 | 164
http://identifiers.org/panther... 151 | 151
http://identifiers.org/panther... 150 | 150
http://identifiers.org/panther... 149 | 149
http://identifiers.org/panther... 146 | 146
http://identifiers.org/panther... 124 | 124
http://identifiers.org/panther... 118 | 118
http://identifiers.org/panther... 116 | 116
http://identifiers.org/panther... 115 | 115
http://identifiers.org/panther... 110 | 110
http://identifiers.org/panther... 107 | 107
http://identifiers.org/panther... 104 | 104
http://identifiers.org/panther... 91 | 91
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 86 | 86
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 67 | 67
http://identifiers.org/panther... 65 | 65
http://identifiers.org/panther... 63 | 63
http://identifiers.org/panther... 61 | 61
http://identifiers.org/panther... 60 | 60
http://identifiers.org/panther... 56 | 56
http://identifiers.org/panther... 54 | 54
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 51 | 51
http://identifiers.org/panther... 47 | 47
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 44 | 44
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 41 | 41
http://identifiers.org/panther... 38 | 38
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 33 | 33
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 31 | 31
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 27 | 27
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 17 | 17
http://identifiers.org/panther... 16 | 16
http://identifiers.org/panther... 15 | 15
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 13 | 13
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 8 | 8
http://identifiers.org/panther... 8 | 8

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Poly [ADP-ribose] polymerase 4 PARP4 Tchem Enzyme -1.45503 26.0 123
FAS-associated factor 1 FAF1 Tbio Non-IDG -1.71858 56.5 209
Adseverin SCIN Tbio Non-IDG -1.90989 89.8 72
Caspase-6 CASP6 Tchem Enzyme -2.49135 293.6 874
Caspase-9 CASP9 Tchem Enzyme -3.44725 2332.0 1313
Lamin-B1 LMNB1 Tbio Non-IDG -2.58749 373.5 496
Caspase-7 CASP7 Tchem Enzyme -2.69052 418.1 800
Gelsolin GSN Tbio Non-IDG -3.11676 1340.4 481
Receptor tyrosine-protein kinase erbB-4 ERBB4 Tclin Kinase -2.78704 558.2 1072
Dual specificity mitogen-activated protein kinase kinase 4 MAP2K4 Tchem Kinase -2.43646 236.7 998