Development Level

Tchem 30 | 1,598
Tbio 26 | 11,445
Tclin 10 | 613
Tdark 1 | 6,588

Collection

Kinase: IDG Consortium (Target... 3 | 125

IMPC Phenotype

preweaning lethality, complete... 5 | 979
preweaning lethality, incomple... 4 | 499
abnormal behavior 3 | 298
decreased body weight 3 | 161
decreased total body fat amoun... 3 | 207
hypoactivity 3 | 132
abnormal gait 2 | 69
decreased circulating triglyce... 2 | 79
decreased vertical activity 2 | 208
embryonic lethality prior to t... 2 | 278
increased circulating alkaline... 2 | 122
increased lean body mass 2 | 172
increased startle reflex 2 | 112
increased total body fat amoun... 2 | 134
male infertility 2 | 123
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal duodenum morphology 1 | 4
abnormal embryo size 1 | 220
abnormal gallbladder morpholog... 1 | 1
abnormal glucose homeostasis 1 | 4
abnormal lens morphology 1 | 81
abnormal locomotor behavior 1 | 24
abnormal testis morphology 1 | 43
abnormal vibrissa morphology 1 | 25
abnormal vocalization 1 | 21
brachydactyly 1 | 19
cataract 1 | 92
decreased circulating LDL chol... 1 | 38
decreased circulating amylase ... 1 | 28
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating insulin ... 1 | 76
decreased circulating phosphat... 1 | 27
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased prepulse inhibition 1 | 82
decreased respiratory quotient 1 | 16
embryonic growth retardation 1 | 106
enlarged gallbladder 1 | 2
enlarged heart 1 | 210
enlarged spleen 1 | 41
hydrometra 1 | 53
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased circulating LDL chol... 1 | 13
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating iron lev... 1 | 30
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased or absent threshold ... 1 | 101
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
short tibia 1 | 97
small epididymis 1 | 3
small superior vagus ganglion 1 | 74
small testis 1 | 58
thrombocytosis 1 | 27
vertebral fusion 1 | 23

Disease

Carcinoma 59 | 11,493
ovarian cancer 43 | 8,520
medulloblastoma, large-cell 38 | 6,241
psoriasis 34 | 6,694
atypical teratoid / rhabdoid tumor 33 | 5,112
ependymoma 33 | 4,679
glioblastoma 32 | 5,792
lung cancer 31 | 4,740
group 3 medulloblastoma 30 | 4,104
osteosarcoma 30 | 7,950
Kidney cancer 26 | 2,613
adult high grade glioma 26 | 3,801
Breast cancer 25 | 3,578
lung adenocarcinoma 24 | 2,716
lung carcinoma 24 | 2,843
primitive neuroectodermal tumor 23 | 3,035
Cancer 22 | 2,499
oligodendroglioma 22 | 2,850
Astrocytoma, Pilocytic 21 | 3,081
astrocytic glioma 21 | 2,597
malignant mesothelioma 21 | 3,232
ulcerative colitis 20 | 1,819
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,989
non-small cell lung cancer 19 | 2,890
colon cancer 18 | 1,478
Pick disease 16 | 1,894
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
pancreatic cancer 16 | 2,398
Autosomal recessive predisposition 15 | 1,442
interstitial cystitis 15 | 2,312
invasive ductal carcinoma 15 | 2,951
subependymal giant cell astrocytoma 15 | 2,287
Bipolar Disorder 14 | 666
Obesity 14 | 678
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,291
pituitary cancer 13 | 1,972
tuberculosis 13 | 2,010
Depressive disorder 12 | 409
Hypertension 12 | 396
Hypertensive disease 12 | 292
Melanoma 11 | 711
Schizophrenia 11 | 1,160
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,962
Alzheimer's disease 10 | 658
breast carcinoma 10 | 1,638
diabetes mellitus 10 | 1,728
Breast Neoplasms 9 | 445
Heart disease 9 | 306
Intellectual disability 9 | 1,016
Mammary Neoplasms 9 | 425
cystic fibrosis 9 | 1,696
group 4 medulloblastoma 9 | 1,855
Cardiomegaly 8 | 116
Cognitive delay 8 | 608
Diabetes Mellitus, Non-Insulin-Dependent 8 | 145
Diabetes Mellitus, Type 2 8 | 142
Dull intelligence 8 | 645
Epilepsy 8 | 792
Global developmental delay 8 | 608
Hyperalgesia 8 | 83
Kidney disease 8 | 430
Liver cancer 8 | 604
Low intelligence 8 | 645
Mental Depression 8 | 333
Mental Retardation 8 | 645
Mental and motor retardation 8 | 608
Mental deficiency 8 | 645
Poor school performance 8 | 645
Pulmonary hypertension 8 | 85
Skin cancer 8 | 469
spina bifida 8 | 1,074
Acquired metabolic disease 7 | 336
Asthma 7 | 385
Cardiomyopathies 7 | 110
Carney complex 7 | 25
Heart failure 7 | 162
Liver Cirrhosis, Experimental 7 | 769
Major Depressive Disorder 7 | 301
Parkinson's disease 7 | 392
Prostatic Neoplasms 7 | 495
Seizures 7 | 596
Short stature 7 | 531
Unipolar Depression 7 | 250
acute myeloid leukemia 7 | 783
astrocytoma 7 | 1,146
gastric carcinoma 7 | 807
nasopharyngeal carcinoma 7 | 1,058
Concave bridge of nose 6 | 195
Depressed nasal bridge 6 | 195
Depressed nasal root/bridge 6 | 195
Hypoplastic mandible condyle 6 | 275
Mandibular hypoplasia 6 | 275
Micrognathism 6 | 275
Muscle hypotonia 6 | 571
Orbital separation excessive 6 | 244
Rheumatoid arthritis 6 | 1,191
active Crohn's disease 6 | 922
adrenocortical carcinoma 6 | 1,428
cutaneous lupus erythematosus 6 | 1,057
ductal carcinoma in situ 6 | 1,745

Tissue

Endocrine System 66 | 18,159
Male tissues 66 | 17,142
Blood and immune system 65 | 16,909
Digestive Tract 65 | 17,369
Female tissues 65 | 17,400
Liver and Pancreas 65 | 16,750
Skin and soft tissues 65 | 17,230
Nervous System 64 | 16,725
Urinary Tract 64 | 16,678
Cardiovascular System 63 | 15,192
Respiratory system 63 | 16,393

Target Family

Enzyme 31 | 4,145
Kinase 23 | 634
Non-IDG 8 | 12,091
Ion Channel 3 | 344
GPCR 2 | 408

PathwayCommons: panther Pathway

http://identifiers.org/panther... 67 | 67
http://identifiers.org/panther... 264 | 264
http://identifiers.org/panther... 197 | 197
http://identifiers.org/panther... 164 | 164
http://identifiers.org/panther... 151 | 151
http://identifiers.org/panther... 150 | 150
http://identifiers.org/panther... 149 | 149
http://identifiers.org/panther... 146 | 146
http://identifiers.org/panther... 124 | 124
http://identifiers.org/panther... 118 | 118
http://identifiers.org/panther... 116 | 116
http://identifiers.org/panther... 115 | 115
http://identifiers.org/panther... 110 | 110
http://identifiers.org/panther... 107 | 107
http://identifiers.org/panther... 104 | 104
http://identifiers.org/panther... 91 | 91
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 86 | 86
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 65 | 65
http://identifiers.org/panther... 63 | 63
http://identifiers.org/panther... 61 | 61
http://identifiers.org/panther... 60 | 60
http://identifiers.org/panther... 56 | 56
http://identifiers.org/panther... 54 | 54
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 51 | 51
http://identifiers.org/panther... 47 | 47
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 44 | 44
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 41 | 41
http://identifiers.org/panther... 38 | 38
http://identifiers.org/panther... 37 | 37
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 33 | 33
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 31 | 31
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 27 | 27
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 17 | 17
http://identifiers.org/panther... 16 | 16
http://identifiers.org/panther... 15 | 15
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 13 | 13
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 8 | 8
http://identifiers.org/panther... 8 | 8

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endothelin-converting enzyme 1 ECE1 Tchem Enzyme -2.56360 355.0 278
Adenylate cyclase type 8 ADCY8 Tbio Enzyme -2.04645 112.4 147
Guanine nucleotide-binding protein subunit alpha-11 GNA11 Tbio Non-IDG -2.80484 555.1 184
Adenylate cyclase type 10 ADCY10 Tchem Enzyme -3.13751 1324.4 108
Protein kinase C beta type PRKCB Tchem Kinase -2.00437 93.5 598
Guanine nucleotide-binding protein subunit alpha-14 GNA14 Tbio Non-IDG -0.78609 4.51 142
Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 Tclin Kinase -3.07197 862.4 2448
Adenylate cyclase type 7 ADCY7 Tbio Enzyme -1.68806 49.1 114
Guanine nucleotide-binding protein G(q) subunit alpha GNAQ Tbio Non-IDG -2.73429 514.5 206
Adenylate cyclase type 6 ADCY6 Tchem Enzyme -2.05332 113.7 111