Development Level

Tbio 11 | 11,445
Tclin 4 | 613
Tchem 3 | 1,598

IMPC Phenotype

preweaning lethality, complete... 3 | 979
embryonic lethality prior to o... 2 | 239
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal pharyngeal arch morph... 1 | 8
decreased circulating triglyce... 1 | 79
embryonic growth retardation 1 | 106
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased mean corpuscular hem... 1 | 96

Disease

group 3 medulloblastoma 11 | 4,104
Carcinoma 10 | 11,493
lung cancer 10 | 4,740
non-small cell lung cancer 10 | 2,890
ovarian cancer 10 | 8,520
medulloblastoma, large-cell 9 | 6,241
primitive neuroectodermal tumor 9 | 3,035
malignant mesothelioma 8 | 3,232
psoriasis 8 | 6,694
glioblastoma 7 | 5,792
atypical teratoid / rhabdoid tumor 6 | 5,112
colon cancer 6 | 1,478
nasopharyngeal carcinoma 6 | 1,058
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
osteosarcoma 5 | 7,950
Cancer 4 | 2,499
Intellectual disability 4 | 1,016
Kidney cancer 4 | 2,613
Malignant tumor of ovary 4 | 25
Waldenstrons macroglobulinemia 4 | 765
adrenocortical carcinoma 4 | 1,428
adult high grade glioma 4 | 3,801
diabetes mellitus 4 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
oligodendroglioma 4 | 2,850
Acute lymphoid leukemia 3 | 25
Acute myeloid leukemia, disease 3 | 30
Acute promyelocytic leukemia, FAB M3 3 | 11
Adenocarcinoma of pancreas 3 | 14
Breast cancer 3 | 3,578
Cognitive delay 3 | 608
Dull intelligence 3 | 645
Global developmental delay 3 | 608
Hypoplastic mandible condyle 3 | 275
Low intelligence 3 | 645
Mandibular hypoplasia 3 | 275
Mental Retardation 3 | 645
Mental and motor retardation 3 | 608
Mental deficiency 3 | 645
Metastatic Breast Carcinoma 3 | 21
Micrognathism 3 | 275
Poor school performance 3 | 645
Short stature 3 | 531
astrocytoma 3 | 1,146
breast carcinoma 3 | 1,638
ductal carcinoma in situ 3 | 1,745
ependymoma 3 | 4,679
lung adenocarcinoma 3 | 2,716
pediatric high grade glioma 3 | 1,064
primary Sjogren syndrome 3 | 735
Adenocarcinoma of lung 2 | 142
Autosomal recessive predisposition 2 | 1,442
Chronic progressive external ophthalmoplegia 2 | 26
Colonic Neoplasms 2 | 142
Convex nasal ridge 2 | 37
Creatine phosphokinase serum increased 2 | 110
Cryptorchidism 2 | 296
Deafness 2 | 198
Disease Models, Animal 2 | 155
Elevated creatine kinase 2 | 110
Endometriosis 2 | 540
Failure to thrive in infancy 2 | 32
Hernia, Inguinal 2 | 89
Hyperkyphosis 2 | 111
Kyphosis deformity of spine 2 | 114
Leukemia 2 | 104
Low Vision 2 | 174
Lymphomatous meningitis 2 | 3
Meningeal Leukemia 2 | 7
Muscle Spasticity 2 | 195
Osteoporosis 2 | 363
Seckel syndrome 2 | 34
Sensorineural Hearing Loss (disorder) 2 | 284
Small head 2 | 374
Vaccinia 2 | 36
Visual Impairment 2 | 174
Werner syndrome 2 | 29
acute myeloid leukemia 2 | 783
acute quadriplegic myopathy 2 | 1,158
dermatomyositis 2 | 966
invasive ductal carcinoma 2 | 2,951
juvenile dermatomyositis 2 | 1,187
pituitary cancer 2 | 1,972
Acute gonococcal cervicitis 1 | 1
Chancroid 1 | 8
Citrobacter Urinary Tract Infection 1 | 1
Diarrhea due to E. Coli 1 | 1
Enterobacter Pneumonia 1 | 2
Escherichia coli urinary tract infection 1 | 1
Haemophilus influenzae pneumonia 1 | 2
Infection due to Pseudomonas aeruginosa 1 | 1
Infectious diarrheal disease 1 | 1
Infectious disorder of joint 1 | 2
Klebsiella Nosocomial Pneumonia 1 | 1
Malignant otitis externa due to Pseudomonas aeruginosa 1 | 4
Moraxella Catarrhalis Chronic Bronchitis 1 | 1
Nosocomial pneumonia 1 | 1
Rhinoscleroma 1 | 5
Skin and Skin Structure Citrobacter Infection 1 | 1
Skin and Skin Structure Pseudomonas Aeruginosa Infection 1 | 1

Tissue

Blood and immune system 18 | 16,909
Cardiovascular System 18 | 15,192
Digestive Tract 18 | 17,369
Endocrine System 18 | 18,159
Female tissues 18 | 17,400
Liver and Pancreas 18 | 16,750
Male tissues 18 | 17,142
Nervous System 18 | 16,725
Respiratory system 18 | 16,393
Skin and soft tissues 18 | 17,230
Urinary Tract 18 | 16,678

Target Family

Enzyme 9 | 4,145
Non-IDG 9 | 12,091

PathwayCommons: panther Pathway

http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 264 | 264
http://identifiers.org/panther... 197 | 197
http://identifiers.org/panther... 164 | 164
http://identifiers.org/panther... 151 | 151
http://identifiers.org/panther... 150 | 150
http://identifiers.org/panther... 149 | 149
http://identifiers.org/panther... 146 | 146
http://identifiers.org/panther... 124 | 124
http://identifiers.org/panther... 118 | 118
http://identifiers.org/panther... 116 | 116
http://identifiers.org/panther... 115 | 115
http://identifiers.org/panther... 110 | 110
http://identifiers.org/panther... 107 | 107
http://identifiers.org/panther... 104 | 104
http://identifiers.org/panther... 91 | 91
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 86 | 86
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 67 | 67
http://identifiers.org/panther... 65 | 65
http://identifiers.org/panther... 63 | 63
http://identifiers.org/panther... 61 | 61
http://identifiers.org/panther... 60 | 60
http://identifiers.org/panther... 56 | 56
http://identifiers.org/panther... 54 | 54
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 51 | 51
http://identifiers.org/panther... 47 | 47
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 44 | 44
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 41 | 41
http://identifiers.org/panther... 38 | 38
http://identifiers.org/panther... 37 | 37
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 33 | 33
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 31 | 31
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 27 | 27
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 17 | 17
http://identifiers.org/panther... 16 | 16
http://identifiers.org/panther... 15 | 15
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 13 | 13
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 8 | 8
http://identifiers.org/panther... 8 | 8

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA topoisomerase 1 TOP1 Tclin Enzyme -3.61701 4015.4 248
DNA topoisomerase 2-alpha TOP2A Tclin Enzyme -2.88264 723.0 847
Replication factor C subunit 2 RFC2 Tbio Non-IDG -1.36589 20.3 293
Replication factor C subunit 1 RFC1 Tbio Non-IDG -1.43459 26.5 198
Replication factor C subunit 3 RFC3 Tbio Non-IDG -1.30866 19.7 176
Histone H3.3C H3F3C Tbio Non-IDG -1.09691 12.4 17
Histone H3.1t HIST3H3 Tbio Non-IDG -1.05426 10.9 1265
DNA polymerase delta subunit 2 POLD2 Tbio Enzyme -0.95222 8.52 115
DNA topoisomerase 2-beta TOP2B Tchem Enzyme -2.47190 253.5 190
DNA primase small subunit PRIM1 Tbio Enzyme -0.87865 7.80 138