Development Level

Tbio 47 | 11,445
Tchem 11 | 1,598
Tclin 11 | 613
Tdark 1 | 6,588

Collection

Kinase: IDG Consortium (Target... 3 | 125
RFA-RM-18-021 3 | 328

IMPC Phenotype

preweaning lethality, complete... 6 | 979
abnormal bone structure 4 | 187
preweaning lethality, incomple... 4 | 499
abnormal behavioral response t... 2 | 66
abnormal retina morphology 2 | 71
convulsive seizures 2 | 13
decreased bone mineral content 2 | 151
decreased circulating fructosa... 2 | 30
decreased circulating serum al... 2 | 82
decreased leukocyte cell numbe... 2 | 73
decreased total body fat amoun... 2 | 207
edema 2 | 59
embryonic growth retardation 2 | 106
embryonic lethality prior to t... 2 | 278
improved glucose tolerance 2 | 79
increased blood urea nitrogen ... 2 | 48
increased mean corpuscular vol... 2 | 92
prenatal lethality prior to he... 2 | 87
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal hair texture 1 | 4
abnormal motor learning 1 | 3
abnormal pericardium morpholog... 1 | 26
abnormal placenta size 1 | 20
abnormal skin coloration 1 | 25
abnormal sleep behavior 1 | 70
abnormal vocalization 1 | 21
absent startle reflex 1 | 24
cardiovascular system phenotyp... 1 | 36
corneal opacity 1 | 32
decreased anxiety-related resp... 1 | 12
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating total pr... 1 | 49
decreased exploration in new e... 1 | 11
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased spleen weight 1 | 10
decreased startle reflex 1 | 75
decreased urine creatinine lev... 1 | 3
embryonic lethality prior to o... 1 | 239
enlarged kidney 1 | 14
fused cornea and lens 1 | 5
fusion of vertebral arches 1 | 7
hemorrhage 1 | 23
increased body length 1 | 32
increased caudal vertebrae num... 1 | 7
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating triglyce... 1 | 42
increased erythrocyte cell num... 1 | 39
increased heart rate variabili... 1 | 7
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
increased red blood cell distr... 1 | 34
increased spleen weight 1 | 10
increased total body fat amoun... 1 | 134
increased urine magnesium leve... 1 | 2
pallor 1 | 34
prolonged PR interval 1 | 15
short tibia 1 | 97
vertebral fusion 1 | 23

Disease

Carcinoma 50 | 11,493
ovarian cancer 40 | 8,520
osteosarcoma 35 | 7,950
psoriasis 34 | 6,694
glioblastoma 27 | 5,792
medulloblastoma, large-cell 27 | 6,241
Breast cancer 24 | 3,578
Kidney cancer 22 | 2,613
atypical teratoid / rhabdoid tumor 22 | 5,112
Cancer 21 | 2,499
lung cancer 21 | 4,740
ependymoma 20 | 4,679
adult high grade glioma 19 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 19 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,989
non-small cell lung cancer 18 | 2,890
Astrocytoma, Pilocytic 17 | 3,081
invasive ductal carcinoma 16 | 2,951
malignant mesothelioma 16 | 3,232
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
lung carcinoma 15 | 2,843
pancreatic cancer 15 | 2,398
acute quadriplegic myopathy 14 | 1,158
breast carcinoma 13 | 1,638
Melanoma 12 | 711
group 4 medulloblastoma 12 | 1,855
juvenile dermatomyositis 12 | 1,187
lung adenocarcinoma 12 | 2,716
primitive neuroectodermal tumor 12 | 3,035
Duchenne muscular dystrophy 11 | 601
Ocular hypertension 11 | 42
Skin cancer 11 | 469
colon cancer 11 | 1,478
cystic fibrosis 11 | 1,696
Open-angle glaucoma 10 | 27
astrocytic glioma 10 | 2,597
group 3 medulloblastoma 10 | 4,104
oligodendroglioma 10 | 2,850
primary pancreatic ductal adenocarcinoma 10 | 1,109
subependymal giant cell astrocytoma 10 | 2,287
Acute lymphoid leukemia 9 | 25
Anaplastic large T-cell systemic malignant lymphoma 9 | 10
Burkitt's lymphoma 9 | 15
Carcinoma of breast 9 | 11
Carcinoma of female breast 9 | 20
Diffuse non-Hodgkin's lymphoma, large cell 9 | 12
Follicular non-Hodgkin's lymphoma 9 | 17
Gestational trophoblastic neoplasia 9 | 14
HER2-positive carcinoma of breast 9 | 21
Hodgkin's disease 9 | 18
Hypertensive disorder 9 | 56
Kaposi's sarcoma 9 | 22
Langerhans cell histiocytosis, disseminated 9 | 10
Liposarcoma 9 | 20
Malignant tumor of head and/or neck 9 | 15
Malignant tumor of ovary 9 | 25
Malignant tumor of prostate 9 | 26
Malignant tumor of stomach 9 | 12
Malignant tumor of testis 9 | 11
Metastatic Breast Carcinoma 9 | 21
Metastatic Prostate Carcinoma 9 | 18
Mycosis fungoides 9 | 29
Nephroblastoma 9 | 51
Neuroblastoma 9 | 80
Non-Hodgkin's lymphoma 9 | 22
Pick disease 9 | 1,894
Rhabdomyosarcoma 9 | 39
Secondary malignant neoplasm of pancreas 9 | 10
diabetes mellitus 9 | 1,728
transitional cell carcinoma 9 | 22
Autosomal recessive predisposition 8 | 1,442
Intellectual disability 8 | 1,016
Multiple myeloma 8 | 1,332
Waldenstrons macroglobulinemia 8 | 765
pediatric high grade glioma 8 | 1,064
pituitary cancer 8 | 1,972
Becker muscular dystrophy 7 | 191
Liver cancer 7 | 604
Rheumatoid arthritis 7 | 1,191
astrocytoma 7 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 510
ductal carcinoma in situ 7 | 1,745
interstitial cystitis 7 | 2,312
tuberculosis 7 | 2,010
ulcerative colitis 7 | 1,819
Blepharoptosis 6 | 231
Breast Neoplasms 6 | 445
Byzanthine arch palate 6 | 194
Distal arthrogryposis 6 | 42
Epilepsy 6 | 792
Lissencephaly 6 | 69
Liver Cirrhosis, Experimental 6 | 769
Seizures 6 | 596
Small head 6 | 374
gastric cancer 6 | 459
nasopharyngeal carcinoma 6 | 1,058
Schizophrenia 5 | 1,160
limb girdle muscular dystrophy 2A 5 | 213
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
spina bifida 5 | 1,074

Tissue

Endocrine System 70 | 18,159
Skin and soft tissues 68 | 17,230
Digestive Tract 67 | 17,369
Female tissues 65 | 17,400
Male tissues 65 | 17,142
Blood and immune system 64 | 16,909
Nervous System 64 | 16,725
Urinary Tract 64 | 16,678
Liver and Pancreas 63 | 16,750
Cardiovascular System 61 | 15,192
Respiratory system 60 | 16,393

Target Family

Non-IDG 48 | 12,091
Kinase 14 | 634
Enzyme 8 | 4,145

PathwayCommons: panther Pathway

http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 264 | 264
http://identifiers.org/panther... 197 | 197
http://identifiers.org/panther... 164 | 164
http://identifiers.org/panther... 151 | 151
http://identifiers.org/panther... 150 | 150
http://identifiers.org/panther... 149 | 149
http://identifiers.org/panther... 146 | 146
http://identifiers.org/panther... 124 | 124
http://identifiers.org/panther... 118 | 118
http://identifiers.org/panther... 116 | 116
http://identifiers.org/panther... 115 | 115
http://identifiers.org/panther... 110 | 110
http://identifiers.org/panther... 107 | 107
http://identifiers.org/panther... 104 | 104
http://identifiers.org/panther... 91 | 91
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 86 | 86
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 67 | 67
http://identifiers.org/panther... 65 | 65
http://identifiers.org/panther... 63 | 63
http://identifiers.org/panther... 61 | 61
http://identifiers.org/panther... 60 | 60
http://identifiers.org/panther... 56 | 56
http://identifiers.org/panther... 54 | 54
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 51 | 51
http://identifiers.org/panther... 47 | 47
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 44 | 44
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 41 | 41
http://identifiers.org/panther... 38 | 38
http://identifiers.org/panther... 37 | 37
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 33 | 33
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 31 | 31
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 27 | 27
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 17 | 17
http://identifiers.org/panther... 16 | 16
http://identifiers.org/panther... 15 | 15
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 13 | 13
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 8 | 8
http://identifiers.org/panther... 8 | 8

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Actin, gamma-enteric smooth muscle ACTG2 Tbio Non-IDG -1.98240 92.4 212
Actin, cytoplasmic 2 ACTG1 Tbio Non-IDG -2.50312 297.3 225
Tubulin beta-4A chain TUBB4A Tclin Non-IDG -2.98371 896.1 90
Myosin-IIIb MYO3B Tbio Kinase -0.73450 5.14 127
Tubulin beta-6 chain TUBB6 Tclin Non-IDG -0.94163 8.01 85
Myosin-4 MYH4 Tbio Non-IDG -1.81214 51.8 52
Myosin-13 MYH13 Tbio Non-IDG -1.26079 16.6 12
Myosin-2 MYH2 Tbio Non-IDG -2.14128 114.9 63
Rho-associated protein kinase 1 ROCK1 Tclin Kinase -2.64622 378.2 461
Myosin-6 MYH6 Tbio Non-IDG -2.95952 901.3 45