Development Level

Tbio 83 | 11,445
Tdark 50 | 6,588
Tchem 9 | 1,598
Tclin 8 | 613

Collection

RFA-RM-18-021 2 | 328
GPCR: IDG Consortium (Targets) 1 | 126
Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 9 | 979
abnormal behavior 4 | 298
abnormal heart morphology 4 | 162
decreased vertical activity 4 | 208
increased lean body mass 4 | 172
preweaning lethality, incomple... 4 | 499
decreased startle reflex 3 | 75
decreased total body fat amoun... 3 | 207
embryonic lethality prior to t... 3 | 278
enlarged heart 3 | 210
increased total body fat amoun... 3 | 134
abnormal gait 2 | 69
abnormal head morphology 2 | 10
abnormal startle reflex 2 | 15
corneal opacity 2 | 32
decreased leukocyte cell numbe... 2 | 73
decreased lymphocyte cell numb... 2 | 83
decreased prepulse inhibition 2 | 82
embryonic lethality prior to o... 2 | 239
impaired glucose tolerance 2 | 75
increased monocyte cell number 2 | 63
increased vertical activity 2 | 24
mammalian phenotype 2 | 17
microphthalmia 2 | 26
prenatal lethality prior to he... 2 | 87
short tibia 2 | 97
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal brain morphology 1 | 13
abnormal eye morphology 1 | 68
abnormal eye size 1 | 7
abnormal femur morphology 1 | 14
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal maxilla morphology 1 | 17
abnormal snout morphology 1 | 23
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating creatini... 1 | 39
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased grip strength 1 | 116
decreased hemoglobin content 1 | 68
decreased large unstained cell... 1 | 11
edema 1 | 59
embryonic growth retardation 1 | 106
hydroencephaly 1 | 14
hydrometra 1 | 53
hydrops fetalis 1 | 1
hyperactivity 1 | 148
increased blood urea nitrogen ... 1 | 48
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating insulin ... 1 | 3
increased hematocrit 1 | 46
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
increased startle reflex 1 | 112
pallor 1 | 34
prenatal lethality 1 | 28
prolonged PR interval 1 | 15
shortened ST segment 1 | 10
small heart 1 | 10
small superior vagus ganglion 1 | 74
thrombocytopenia 1 | 56

Disease

Carcinoma 140 | 11,493
Kidney cancer 79 | 2,613
psoriasis 67 | 6,694
ovarian cancer 53 | 8,520
Breast cancer 51 | 3,578
atypical teratoid / rhabdoid tumor 49 | 5,112
glioblastoma 49 | 5,792
ependymoma 46 | 4,679
medulloblastoma, large-cell 46 | 6,241
osteosarcoma 46 | 7,950
lung cancer 43 | 4,740
lung carcinoma 39 | 2,843
Cancer 37 | 2,499
group 3 medulloblastoma 31 | 4,104
oligodendroglioma 31 | 2,850
Astrocytoma, Pilocytic 30 | 3,081
group 4 medulloblastoma 30 | 1,855
invasive ductal carcinoma 29 | 2,951
pancreatic cancer 29 | 2,398
intraductal papillary-mucinous neoplasm (IPMN) 28 | 3,291
interstitial cystitis 27 | 2,312
Liver cancer 26 | 604
adult high grade glioma 25 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 25 | 2,955
malignant mesothelioma 25 | 3,232
lung adenocarcinoma 24 | 2,716
primitive neuroectodermal tumor 24 | 3,035
non-small cell lung cancer 23 | 2,890
astrocytic glioma 22 | 2,597
ductal carcinoma in situ 22 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 22 | 2,989
breast carcinoma 21 | 1,638
Melanoma 20 | 711
Skin cancer 20 | 469
subependymal giant cell astrocytoma 19 | 2,287
cystic fibrosis 18 | 1,696
Endometrial cancer 17 | 311
Schizophrenia 17 | 1,160
pediatric high grade glioma 17 | 1,064
Pick disease 16 | 1,894
pituitary cancer 16 | 1,972
ulcerative colitis 15 | 1,819
colon cancer 14 | 1,478
Alcoholic Intoxication, Chronic 13 | 289
Autosomal recessive predisposition 13 | 1,442
Bipolar Disorder 13 | 666
Breast Neoplasms 12 | 445
primary pancreatic ductal adenocarcinoma 12 | 1,109
Intellectual disability 11 | 1,016
Prostatic Neoplasms 11 | 495
astrocytoma 11 | 1,146
cutaneous lupus erythematosus 11 | 1,057
diabetes mellitus 11 | 1,728
esophageal adenocarcinoma 11 | 737
fibroadenoma 11 | 559
Mammary Neoplasms 10 | 425
Rheumatoid arthritis 10 | 1,191
juvenile dermatomyositis 10 | 1,187
non primary Sjogren syndrome sicca 10 | 891
tuberculosis 10 | 2,010
Colonic Neoplasms 9 | 142
Colorectal Neoplasms 9 | 243
Obesity 9 | 678
Osteoporosis 9 | 363
Vascular disease 9 | 319
adrenocortical carcinoma 9 | 1,428
gastric carcinoma 9 | 807
Alzheimer's disease 8 | 658
Duchenne muscular dystrophy 8 | 601
Stomach Neoplasms 8 | 300
active Crohn's disease 8 | 922
Down syndrome 7 | 499
Endometriosis 7 | 540
Liver Cirrhosis, Experimental 7 | 769
Lung Neoplasms 7 | 232
Neoplasm Invasiveness 7 | 161
Neoplasm Metastasis 7 | 168
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 510
urothelial carcinoma 7 | 318
Acquired metabolic disease 6 | 336
Adenoma 6 | 167
Asthma 6 | 385
Autistic Disorder 6 | 364
Blastic phase chronic myeloid leukemia 6 | 58
Chronic Myelocytic Leukemia Accelerated Phase 6 | 59
Disease Progression 6 | 136
Dull intelligence 6 | 645
Hypoplastic mandible condyle 6 | 275
Low intelligence 6 | 645
Mandibular hypoplasia 6 | 275
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Micrognathism 6 | 275
Poor school performance 6 | 645
Short stature 6 | 531
acute quadriplegic myopathy 6 | 1,158
aldosterone-producing adenoma 6 | 665
posterior fossa group A ependymoma 6 | 468
spina bifida 6 | 1,074
primary Sjogren syndrome 5 | 735

Tissue

Endocrine System 148 | 18,159
Female tissues 147 | 17,400
Nervous System 147 | 16,725
Male tissues 144 | 17,142
Digestive Tract 142 | 17,369
Skin and soft tissues 141 | 17,230
Liver and Pancreas 136 | 16,750
Urinary Tract 136 | 16,678
Respiratory system 134 | 16,393
Blood and immune system 133 | 16,909
Cardiovascular System 113 | 15,192

Target Family

Non-IDG 119 | 12,091
Kinase 14 | 634
GPCR 13 | 408
Transcription Factor 3 | 1,400
Enzyme 1 | 4,145

PathwayCommons: panther Pathway

http://identifiers.org/panther... 150 | 150
http://identifiers.org/panther... 264 | 264
http://identifiers.org/panther... 197 | 197
http://identifiers.org/panther... 164 | 164
http://identifiers.org/panther... 151 | 151
http://identifiers.org/panther... 149 | 149
http://identifiers.org/panther... 146 | 146
http://identifiers.org/panther... 124 | 124
http://identifiers.org/panther... 118 | 118
http://identifiers.org/panther... 116 | 116
http://identifiers.org/panther... 115 | 115
http://identifiers.org/panther... 110 | 110
http://identifiers.org/panther... 107 | 107
http://identifiers.org/panther... 104 | 104
http://identifiers.org/panther... 91 | 91
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 86 | 86
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 67 | 67
http://identifiers.org/panther... 65 | 65
http://identifiers.org/panther... 63 | 63
http://identifiers.org/panther... 61 | 61
http://identifiers.org/panther... 60 | 60
http://identifiers.org/panther... 56 | 56
http://identifiers.org/panther... 54 | 54
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 51 | 51
http://identifiers.org/panther... 47 | 47
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 44 | 44
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 41 | 41
http://identifiers.org/panther... 38 | 38
http://identifiers.org/panther... 37 | 37
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 33 | 33
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 31 | 31
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 27 | 27
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 17 | 17
http://identifiers.org/panther... 16 | 16
http://identifiers.org/panther... 15 | 15
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 13 | 13
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 8 | 8
http://identifiers.org/panther... 8 | 8

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Actin, gamma-enteric smooth muscle ACTG2 Tbio Non-IDG -1.98240 92.4 212
Actin, cytoplasmic 2 ACTG1 Tbio Non-IDG -2.50312 297.3 225
Cadherin EGF LAG seven-pass G-type receptor 2 CELSR2 Tbio GPCR -1.22995 16.7 139
Cadherin-22 CDH22 Tbio Non-IDG -0.84316 8.75 102
Protocadherin gamma-A1 PCDHGA1 Tdark Non-IDG 0.57 0.27 131
Protocadherin alpha-5 PCDHA5 Tdark Non-IDG 0.00000 119
Protocadherin gamma-A8 PCDHGA8 Tdark Non-IDG 0.00000 1.00 96
Protocadherin gamma-A2 PCDHGA2 Tdark Non-IDG 1.00 0.04 55
Protocadherin gamma-A3 PCDHGA3 Tbio Non-IDG -0.38917 3.38 181
Protocadherin gamma-A10 PCDHGA10 Tdark Non-IDG 1.20 0.10 29