Development Level

Tbio 19 | 11,445
Tchem 11 | 1,598
Tclin 8 | 613

IMPC Phenotype

preweaning lethality, incomple... 3 | 499
abnormal testis morphology 2 | 43
decreased bone mineral content 2 | 151
decreased circulating bilirubi... 2 | 19
decreased vertical activity 2 | 208
enlarged heart 2 | 210
preweaning lethality, complete... 2 | 979
small testis 2 | 58
thrombocytopenia 2 | 56
abnormal behavior 1 | 298
abnormal heart morphology 1 | 162
abnormal seminal vesicle morph... 1 | 114
abnormal snout morphology 1 | 23
decreased circulating creatini... 1 | 39
decreased circulating phosphat... 1 | 27
decreased lean body mass 1 | 135
decreased mean corpuscular vol... 1 | 79
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hydrometra 1 | 53
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased mean platelet volume 1 | 45
increased total body fat amoun... 1 | 134
pale yolk sac 1 | 25
premature death 1 | 5
small superior vagus ganglion 1 | 74
tremors 1 | 39

Disease

Carcinoma 31 | 11,493
Cancer 22 | 2,499
Autosomal recessive predisposition 21 | 1,442
Cerebrovascular disease 19 | 238
ovarian cancer 18 | 8,520
Coronary artery disease 17 | 268
Thrombophilia 17 | 38
Atherosclerosis 16 | 291
Pulmonary embolism 16 | 55
Thrombosis 15 | 46
Venous Thrombosis 15 | 47
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,962
Hypertension 14 | 396
Thrombocytopenia 14 | 197
lung cancer 14 | 4,740
lung carcinoma 14 | 2,843
psoriasis 14 | 6,694
Disseminated intravascular coagulation 13 | 38
pancreatic cancer 13 | 2,398
Epistaxis 12 | 43
Kidney disease 12 | 430
diabetes mellitus 12 | 1,728
invasive ductal carcinoma 12 | 2,951
lung adenocarcinoma 12 | 2,716
osteosarcoma 12 | 7,950
Menorrhagia 11 | 25
adult high grade glioma 11 | 3,801
atypical teratoid / rhabdoid tumor 11 | 5,112
cystic fibrosis 11 | 1,696
Heart disease 10 | 306
Liver Cirrhosis, Experimental 10 | 769
Liver disease 10 | 237
Protein C deficiency 10 | 19
Purpura 10 | 43
interstitial cystitis 10 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
non-small cell lung cancer 10 | 2,890
tuberculosis 10 | 2,010
Breast cancer 9 | 3,578
Hemarthrosis 9 | 12
Hypertensive disease 9 | 292
Peripheral vascular disease 9 | 87
ependymoma 9 | 4,679
glioblastoma 9 | 5,792
Astrocytoma, Pilocytic 8 | 3,081
Bernard-Soulier syndrome 8 | 14
Ecchymosis 8 | 66
Glanzmann's thrombasthenia 8 | 23
Hemophilia B 8 | 11
Hepatic veno-occlusive disease 8 | 16
Increased tendency to bruise 8 | 66
Vascular disease 8 | 319
Von Willebrand's disease 8 | 19
breast carcinoma 8 | 1,638
malignant mesothelioma 8 | 3,232
Atopic dermatitis 7 | 952
Bleeding tendency 7 | 37
Cerebral Hemorrhage 7 | 42
Congenital afibrinogenemia 7 | 11
Gastrointestinal Hemorrhage 7 | 52
Gingival Hemorrhage 7 | 18
Hemorrhage 7 | 19
Hypersensitivity reaction type II disease 7 | 253
Stomach Neoplasms 7 | 300
Thromboembolism 7 | 15
ductal carcinoma in situ 7 | 1,745
group 3 medulloblastoma 7 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
medulloblastoma, large-cell 7 | 6,241
ulcerative colitis 7 | 1,819
Anemia 6 | 365
Bleeding time prolonged 6 | 31
Cerebrovascular accident 6 | 63
Chemical and Drug Induced Liver Injury 6 | 195
Deep Vein Thrombosis 6 | 8
Factor VIII deficiency 6 | 10
Factor XI Deficiency 6 | 12
Factor XII deficiency 6 | 13
Kidney cancer 6 | 2,613
Liver Cirrhosis 6 | 181
Lung disease 6 | 142
Partial thromboplastin time increased (finding) 6 | 11
Thrombophlebitis 6 | 19
Vasculitis 6 | 80
esophageal adenocarcinoma 6 | 737
gastric carcinoma 6 | 807
oligodendroglioma 6 | 2,850
Arthritis, Juvenile 5 | 126
Brain Ischemia 5 | 110
Cholestasis 5 | 155
Connective tissue disease 5 | 62
Decreased platelet count 5 | 111
Highly variable severity 5 | 157
Intracranial Hemorrhages 5 | 16
Juvenile arthritis 5 | 126
Myocardial Infarction 5 | 151
Schizophrenia 5 | 1,160
Variable expressivity 5 | 157
gastric cancer 5 | 459
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989

Tissue

Digestive Tract 37 | 17,369
Endocrine System 36 | 18,159
Liver and Pancreas 36 | 16,750
Urinary Tract 36 | 16,678
Skin and soft tissues 35 | 17,230
Female tissues 34 | 17,400
Male tissues 34 | 17,142
Blood and immune system 33 | 16,909
Respiratory system 32 | 16,393
Nervous System 30 | 16,725
Cardiovascular System 27 | 15,192

Target Family

Non-IDG 23 | 12,091
Enzyme 13 | 4,145
GPCR 2 | 408

PathwayCommons: panther Pathway

http://identifiers.org/panther... 38 | 38
http://identifiers.org/panther... 264 | 264
http://identifiers.org/panther... 197 | 197
http://identifiers.org/panther... 164 | 164
http://identifiers.org/panther... 151 | 151
http://identifiers.org/panther... 150 | 150
http://identifiers.org/panther... 149 | 149
http://identifiers.org/panther... 146 | 146
http://identifiers.org/panther... 124 | 124
http://identifiers.org/panther... 118 | 118
http://identifiers.org/panther... 116 | 116
http://identifiers.org/panther... 115 | 115
http://identifiers.org/panther... 110 | 110
http://identifiers.org/panther... 107 | 107
http://identifiers.org/panther... 104 | 104
http://identifiers.org/panther... 91 | 91
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 86 | 86
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 67 | 67
http://identifiers.org/panther... 65 | 65
http://identifiers.org/panther... 63 | 63
http://identifiers.org/panther... 61 | 61
http://identifiers.org/panther... 60 | 60
http://identifiers.org/panther... 56 | 56
http://identifiers.org/panther... 54 | 54
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 51 | 51
http://identifiers.org/panther... 47 | 47
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 44 | 44
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 41 | 41
http://identifiers.org/panther... 37 | 37
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 33 | 33
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 31 | 31
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 27 | 27
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 17 | 17
http://identifiers.org/panther... 16 | 16
http://identifiers.org/panther... 15 | 15
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 13 | 13
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 8 | 8
http://identifiers.org/panther... 8 | 8

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proteinase-activated receptor 4 F2RL3 Tchem GPCR -1.50044 34.1 276
Alpha-1-antitrypsin SERPINA1 Tbio Non-IDG -3.74914 5601.8 1083
Platelet glycoprotein V GP5 Tbio Non-IDG -2.81536 644.5 88
Platelet glycoprotein Ib beta chain GP1BB Tbio Non-IDG -1.79873 57.4 87
Fibrinogen alpha chain FGA Tbio Non-IDG -2.88066 753.1 595
Fibrinogen gamma chain FGG Tbio Non-IDG -2.21041 158.7 384
Endothelial protein C receptor PROCR Tbio Non-IDG -2.70271 541.0 367
Proteinase-activated receptor 1 F2R Tclin GPCR -2.78393 551.0 453
Coagulation factor VIII F8 Tbio Non-IDG -3.59602 3983.5 652
Tissue-type plasminogen activator PLAT Tclin Enzyme -3.71677 5819.3 555