Development Level

Tbio 19 | 11,445
Tchem 8 | 1,598
Tclin 2 | 613
Tdark 1 | 6,588

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

abnormal bone mineralization 2 | 38
decreased body weight 2 | 161
decreased circulating creatini... 2 | 39
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
increased lean body mass 2 | 172
preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal bone structure 1 | 187
abnormal cranium morphology 1 | 36
abnormal digit morphology 1 | 10
abnormal embryo size 1 | 220
abnormal retina morphology 1 | 71
abnormal spleen morphology 1 | 55
decreased IgG3 level 1 | 1
decreased bone mineral density 1 | 126
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased heart left ventricle... 1 | 28
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased mature B cell number 1 | 7
decreased spleen weight 1 | 10
decreased thermal nociceptive ... 1 | 2
embryonic growth retardation 1 | 106
enlarged kidney 1 | 14
enlarged lymph nodes 1 | 37
eye hemorrhage 1 | 1
increased IgG1 level 1 | 1
increased IgM level 1 | 1
increased T cell number 1 | 6
increased blood urea nitrogen ... 1 | 48
increased body weight 1 | 25
increased circulating alkaline... 1 | 122
increased erythrocyte cell num... 1 | 39
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
increased spleen weight 1 | 10
increased total body fat amoun... 1 | 134
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97

Disease

Carcinoma 27 | 11,493
osteosarcoma 19 | 7,950
ovarian cancer 16 | 8,520
glioblastoma 14 | 5,792
medulloblastoma, large-cell 14 | 6,241
psoriasis 14 | 6,694
Cancer 13 | 2,499
Kidney cancer 13 | 2,613
ependymoma 12 | 4,679
atypical teratoid / rhabdoid tumor 11 | 5,112
interstitial cystitis 11 | 2,312
lung cancer 11 | 4,740
Breast cancer 10 | 3,578
invasive ductal carcinoma 10 | 2,951
Schizophrenia 9 | 1,160
adult high grade glioma 9 | 3,801
lung carcinoma 9 | 2,843
subependymal giant cell astrocytoma 9 | 2,287
Astrocytoma, Pilocytic 8 | 3,081
malignant mesothelioma 8 | 3,232
ulcerative colitis 8 | 1,819
astrocytic glioma 7 | 2,597
non-small cell lung cancer 7 | 2,890
pituitary cancer 7 | 1,972
Waldenstrons macroglobulinemia 6 | 765
cystic fibrosis 6 | 1,696
group 3 medulloblastoma 6 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
oligodendroglioma 6 | 2,850
pancreatic cancer 6 | 2,398
primitive neuroectodermal tumor 6 | 3,035
breast carcinoma 5 | 1,638
ductal carcinoma in situ 5 | 1,745
group 4 medulloblastoma 5 | 1,855
juvenile dermatomyositis 5 | 1,187
lung adenocarcinoma 5 | 2,716
primary Sjogren syndrome 5 | 735
Bipolar Disorder 4 | 666
Diffuse large B-cell lymphoma 4 | 39
Intellectual disability 4 | 1,016
Liver cancer 4 | 604
Lymphoma, Large B-Cell, Diffuse 4 | 34
Pick disease 4 | 1,894
follicular lymphoma 4 | 20
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
nasopharyngeal carcinoma 4 | 1,058
spina bifida 4 | 1,074
Autosomal recessive predisposition 3 | 1,442
Colorectal Neoplasms 3 | 243
Colorectal cancer 3 | 25
DOID:2627 3 | 94
Endometrial cancer 3 | 311
Endometriosis 3 | 540
Epilepsy 3 | 792
Frontal bossing 3 | 157
Immunologic Deficiency Syndromes 3 | 113
Melanoma 3 | 711
Neoplasm Metastasis 3 | 168
Renal Cell Carcinoma 3 | 214
Rheumatoid arthritis 3 | 1,191
Seizures 3 | 596
active ulcerative colitis 3 | 764
diabetes mellitus 3 | 1,728
hepatocellular carcinoma 3 | 547
medulloblastoma 3 | 720
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
primary pancreatic ductal adenocarcinoma 3 | 1,109
progressive supranuclear palsy 3 | 676
tuberculosis 3 | 2,010
tuberculosis and treatment for 3 months 3 | 179
Attention deficit hyperactivity disorder 2 | 278
Carcinoma, Hepatocellular 2 | 228
Concave bridge of nose 2 | 195
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Depressive disorder 2 | 409
Diarrhea 2 | 253
Failure to gain weight 2 | 365
Hypothyroidism 2 | 122
Infantile onset 2 | 238
Liver Cirrhosis, Experimental 2 | 769
Liver carcinoma 2 | 240
Microstomia 2 | 78
Myopia 2 | 176
Pediatric failure to thrive 2 | 365
Polymicrogyria 2 | 48
Skin cancer 2 | 469
Stomach Neoplasms 2 | 300
Type 2 diabetes mellitus 2 | 272
Vascular disease 2 | 319
Ventricular Septal Defects 2 | 119
active Crohn's disease 2 | 922
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
atypical teratoid/rhabdoid tumor 2 | 357
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
mucosa-associated lymphoid tissue lymphoma 2 | 484
pancreatic carcinoma 2 | 562
pediatric high grade glioma 2 | 1,064

Tissue

Endocrine System 30 | 18,159
Female tissues 30 | 17,400
Nervous System 30 | 16,725
Skin and soft tissues 30 | 17,230
Blood and immune system 29 | 16,909
Digestive Tract 29 | 17,369
Male tissues 29 | 17,142
Respiratory system 29 | 16,393
Urinary Tract 29 | 16,678
Liver and Pancreas 27 | 16,750
Cardiovascular System 26 | 15,192

Target Family

Non-IDG 11 | 12,091
Enzyme 9 | 4,145
Kinase 7 | 634
Transcription Factor 3 | 1,400

PathwayCommons: panther Pathway

http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 264 | 264
http://identifiers.org/panther... 197 | 197
http://identifiers.org/panther... 164 | 164
http://identifiers.org/panther... 151 | 151
http://identifiers.org/panther... 150 | 150
http://identifiers.org/panther... 149 | 149
http://identifiers.org/panther... 146 | 146
http://identifiers.org/panther... 124 | 124
http://identifiers.org/panther... 118 | 118
http://identifiers.org/panther... 116 | 116
http://identifiers.org/panther... 115 | 115
http://identifiers.org/panther... 110 | 110
http://identifiers.org/panther... 107 | 107
http://identifiers.org/panther... 104 | 104
http://identifiers.org/panther... 91 | 91
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 86 | 86
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 67 | 67
http://identifiers.org/panther... 65 | 65
http://identifiers.org/panther... 63 | 63
http://identifiers.org/panther... 61 | 61
http://identifiers.org/panther... 60 | 60
http://identifiers.org/panther... 56 | 56
http://identifiers.org/panther... 54 | 54
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 51 | 51
http://identifiers.org/panther... 47 | 47
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 44 | 44
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 41 | 41
http://identifiers.org/panther... 38 | 38
http://identifiers.org/panther... 37 | 37
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 33 | 33
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 31 | 31
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 27 | 27
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 17 | 17
http://identifiers.org/panther... 16 | 16
http://identifiers.org/panther... 15 | 15
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 13 | 13
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 8 | 8
http://identifiers.org/panther... 8 | 8

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nuclear factor of activated T-cells, cytoplasmic 4 NFATC4 Tbio Transcription Factor -1.93766 88.3 358
Nuclear factor of activated T-cells, cytoplasmic 2 NFATC2 Tbio Transcription Factor -2.43207 259.4 365
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 PLCG2 Tchem Enzyme -2.41628 245.1 733
Cell division control protein 42 homolog CDC42 Tchem Enzyme -3.37283 2188.5 380
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta PIK3C2B Tchem Kinase -1.50611 34.7 157
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha PIK3C2A Tchem Kinase -3.50398 3129.0 525
Netrin-G2 NTNG2 Tbio Non-IDG -1.23569 19.9 79
Rho-related GTP-binding protein RhoU RHOU Tbio Enzyme -1.30084 24.8 95
Netrin-3 NTN3 Tdark Non-IDG -0.56638 4.07 82
Netrin-4 NTN4 Tbio Non-IDG -1.39922 32.7 139