Development Level

Tbio 13 | 11,445
Tchem 5 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
decreased bone mineral content 1 | 151
decreased neutrophil cell numb... 1 | 42
enlarged heart 1 | 210
enlarged spleen 1 | 41
increased blood urea nitrogen ... 1 | 48
increased circulating alkaline... 1 | 122
increased circulating triglyce... 1 | 42
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 17 | 11,493
osteosarcoma 12 | 7,950
ovarian cancer 12 | 8,520
Cancer 11 | 2,499
lung cancer 11 | 4,740
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
lung carcinoma 8 | 2,843
malignant mesothelioma 8 | 3,232
Astrocytoma, Pilocytic 7 | 3,081
atypical teratoid / rhabdoid tumor 7 | 5,112
ependymoma 7 | 4,679
glioblastoma 7 | 5,792
Kidney cancer 6 | 2,613
invasive ductal carcinoma 6 | 2,951
tuberculosis 6 | 2,010
Schizophrenia 5 | 1,160
Waldenstrons macroglobulinemia 5 | 765
adult high grade glioma 5 | 3,801
cystic fibrosis 5 | 1,696
medulloblastoma, large-cell 5 | 6,241
oligodendroglioma 5 | 2,850
pancreatic cancer 5 | 2,398
subependymal giant cell astrocytoma 5 | 2,287
ulcerative colitis 5 | 1,819
Pick disease 4 | 1,894
astrocytic glioma 4 | 2,597
ductal carcinoma in situ 4 | 1,745
group 3 medulloblastoma 4 | 4,104
group 4 medulloblastoma 4 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
non-small cell lung cancer 4 | 2,890
primary pancreatic ductal adenocarcinoma 4 | 1,109
primitive neuroectodermal tumor 4 | 3,035
Alzheimer's disease 3 | 658
Breast cancer 3 | 3,578
Liver Cirrhosis, Experimental 3 | 769
Neurodegenerative disease 3 | 414
diabetes mellitus 3 | 1,728
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
primary Sjogren syndrome 3 | 735
psoriasis 3 | 6,694
Alcoholic Intoxication, Chronic 2 | 289
Autosomal recessive predisposition 2 | 1,442
Bipolar Disorder 2 | 666
Blastic phase chronic myeloid leukemia 2 | 58
Chronic Myelocytic Leukemia Accelerated Phase 2 | 59
Chronic phase chronic myeloid leukemia 2 | 45
Depressive disorder 2 | 409
Down syndrome 2 | 499
Epilepsy 2 | 792
Liver diseases 2 | 87
Lymphoma, T-Cell, Peripheral 2 | 9
Melanoma 2 | 711
Mental Depression 2 | 333
Multiple myeloma 2 | 1,332
Orofacial cleft 2 | 54
Paranoid Schizophrenia 2 | 18
Parkinson's disease 2 | 392
Peripheral T-cell lymphoma 2 | 25
Philadelphia Chromosome Positive Chronic Myelocytic Leukemia 2 | 45
Philadelphia chromosome-positive acute lymphoblastic leukemia 2 | 47
Proteinuria 2 | 144
Stomach Neoplasms 2 | 300
atypical teratoid/rhabdoid tumor 2 | 357
colon cancer 2 | 1,478
gastric carcinoma 2 | 807
juvenile dermatomyositis 2 | 1,187
lung adenocarcinoma 2 | 2,716
medulloblastoma 2 | 720
spina bifida 2 | 1,074
urothelial carcinoma 2 | 318
Age related macular degeneration 1 | 72
Agyria 1 | 15
Angioimmunoblastic Lymphadenopathy 1 | 4
Brain disease 1 | 96
Carcinoma, Renal Cell 1 | 124
Citrullinemia 1 | 14
Congenital diaphragmatic hernia 1 | 67
Congenital hypoplasia of breast 1 | 25
Decreased bone mineral density Z score 1 | 31
Glucose Intolerance 1 | 19
Hirsutism 1 | 47
Hypogonadism, Isolated Hypogonadotropic 1 | 71
Hypogonadotropic hypogonadism 1 | 89
Immunoblastic Lymphadenopathy 1 | 4
Impaired glucose tolerance 1 | 28
Juvenile Myelomonocytic Leukemia 1 | 21
Leukemia, Myelomonocytic, Juvenile 1 | 20
Lymphatic obstruction 1 | 21
Lymphoma, T-Cell, Cutaneous 1 | 22
Macular degeneration 1 | 65
Metabolic acidosis 1 | 90
Oculomotor Nerve Paralysis 1 | 4
Onset of lymphedema around puberty 1 | 21
Renal Cell Carcinoma 1 | 214
Retinitis pigmentosa 47 1 | 4
Small testicle 1 | 75
chorea-acanthocytosis 1 | 12
chronic kidney disease 1 | 90

Tissue

Digestive Tract 19 | 17,369
Endocrine System 19 | 18,159
Female tissues 19 | 17,400
Male tissues 19 | 17,142
Nervous System 19 | 16,725
Skin and soft tissues 19 | 17,230
Blood and immune system 18 | 16,909
Liver and Pancreas 18 | 16,750
Respiratory system 18 | 16,393
Urinary Tract 18 | 16,678
Cardiovascular System 17 | 15,192

Target Family

Enzyme 8 | 4,145
Non-IDG 6 | 12,091
Kinase 5 | 634

PathwayCommons: panther Pathway

http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 264 | 264
http://identifiers.org/panther... 197 | 197
http://identifiers.org/panther... 164 | 164
http://identifiers.org/panther... 151 | 151
http://identifiers.org/panther... 150 | 150
http://identifiers.org/panther... 149 | 149
http://identifiers.org/panther... 146 | 146
http://identifiers.org/panther... 124 | 124
http://identifiers.org/panther... 118 | 118
http://identifiers.org/panther... 116 | 116
http://identifiers.org/panther... 115 | 115
http://identifiers.org/panther... 110 | 110
http://identifiers.org/panther... 107 | 107
http://identifiers.org/panther... 104 | 104
http://identifiers.org/panther... 91 | 91
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 86 | 86
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 67 | 67
http://identifiers.org/panther... 65 | 65
http://identifiers.org/panther... 63 | 63
http://identifiers.org/panther... 61 | 61
http://identifiers.org/panther... 60 | 60
http://identifiers.org/panther... 56 | 56
http://identifiers.org/panther... 54 | 54
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 51 | 51
http://identifiers.org/panther... 47 | 47
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 44 | 44
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 41 | 41
http://identifiers.org/panther... 38 | 38
http://identifiers.org/panther... 37 | 37
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 33 | 33
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 31 | 31
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 27 | 27
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 17 | 17
http://identifiers.org/panther... 16 | 16
http://identifiers.org/panther... 15 | 15
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 13 | 13
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 8 | 8
http://identifiers.org/panther... 8 | 8

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tyrosine-protein kinase FRK FRK Tchem Kinase -1.68365 49.2 394
Dihydropyrimidinase-related protein 1 CRMP1 Tbio Enzyme -1.60377 40.8 318
Semaphorin-4D SEMA4D Tbio Non-IDG -2.18250 176.3 525
Rho guanine nucleotide exchange factor 1 ARHGEF1 Tbio Non-IDG -2.94737 852.2 207
Semaphorin-3A SEMA3A Tbio Non-IDG -2.70786 548.1 185
Tyrosine-protein kinase Fes/Fps FES Tchem Kinase -3.05038 1109.2 314
Serine/threonine-protein kinase PAK 1 PAK1 Tchem Kinase -2.29299 237.8 1060
Ras-related C3 botulinum toxin substrate 2 RAC2 Tbio Enzyme -2.89402 669.8 273
Plexin-A1 PLXNA1 Tbio Non-IDG -1.90927 78.9 116
Plexin-B1 PLXNB1 Tbio Non-IDG -1.81774 64.5 140