Development Level

Tchem 38 | 1,598
Tbio 15 | 11,445
Tclin 9 | 613
Tdark 1 | 6,588

Collection

RFA-RM-18-021 6 | 328
Kinase: IDG Consortium (Target... 4 | 125
Ion Channel: IDG Consortium (T... 2 | 99
GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal behavior 3 | 298
decreased vertical activity 3 | 208
preweaning lethality, incomple... 3 | 499
abnormal embryo size 2 | 220
abnormal vibrissa morphology 2 | 25
cyanosis 2 | 7
edema 2 | 59
embryonic lethality prior to t... 2 | 278
hemorrhage 2 | 23
impaired glucose tolerance 2 | 75
respiratory system phenotype 2 | 2
abnormal behavioral response t... 1 | 66
abnormal eye morphology 1 | 68
abnormal facial morphology 1 | 17
abnormal limb morphology 1 | 13
abnormal placenta vasculature 1 | 2
abnormal tail morphology 1 | 25
abnormal testis morphology 1 | 43
absent pinna reflex 1 | 23
brachydactyly 1 | 19
decreased basophil cell number 1 | 16
decreased circulating bilirubi... 1 | 19
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased circulating unsatura... 1 | 2
decreased eosinophil cell numb... 1 | 24
decreased large unstained cell... 1 | 11
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased neutrophil cell numb... 1 | 42
decreased respiratory quotient 1 | 16
embryonic lethality prior to o... 1 | 239
hyperactivity 1 | 148
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased circulating alanine ... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating iron lev... 1 | 30
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 39
increased hematocrit 1 | 46
increased mean platelet volume 1 | 45
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
male infertility 1 | 123
premature death 1 | 5
prenatal lethality 1 | 28
prolonged PR interval 1 | 15
small testis 1 | 58

Disease

Carcinoma 53 | 11,493
osteosarcoma 33 | 7,950
ovarian cancer 30 | 8,520
psoriasis 30 | 6,694
atypical teratoid / rhabdoid tumor 29 | 5,112
medulloblastoma, large-cell 29 | 6,241
glioblastoma 28 | 5,792
ependymoma 25 | 4,679
group 3 medulloblastoma 25 | 4,104
Cancer 21 | 2,499
Alzheimer's disease 20 | 658
Schizophrenia 19 | 1,160
primitive neuroectodermal tumor 17 | 3,035
Astrocytoma, Pilocytic 16 | 3,081
lung cancer 16 | 4,740
oligodendroglioma 16 | 2,850
adult high grade glioma 15 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,291
lung carcinoma 15 | 2,843
Kidney cancer 13 | 2,613
subependymal giant cell astrocytoma 13 | 2,287
Bipolar Disorder 12 | 666
lung adenocarcinoma 12 | 2,716
Pick disease 11 | 1,894
astrocytic glioma 11 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
malignant mesothelioma 10 | 3,232
pancreatic cancer 10 | 2,398
pediatric high grade glioma 10 | 1,064
Epilepsy 9 | 792
diabetes mellitus 9 | 1,728
Breast cancer 8 | 3,578
Depressive disorder 8 | 409
Hyperalgesia 8 | 83
Neurodegenerative disease 8 | 414
astrocytoma 8 | 1,146
interstitial cystitis 8 | 2,312
invasive ductal carcinoma 8 | 2,951
non-small cell lung cancer 8 | 2,890
pituitary cancer 8 | 1,972
Disease Models, Animal 7 | 155
Down syndrome 7 | 499
Mental Depression 7 | 333
Parkinson's disease 7 | 392
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
Amyloidosis 6 | 67
Intellectual disability 6 | 1,016
Rheumatoid arthritis 6 | 1,191
group 4 medulloblastoma 6 | 1,855
progressive supranuclear palsy 6 | 676
spina bifida 6 | 1,074
tuberculosis 6 | 2,010
ulcerative colitis 6 | 1,819
Alzheimer Disease 5 | 83
Asthma 5 | 385
Autosomal recessive predisposition 5 | 1,442
Biliary dyskinesia 5 | 7
Brain Ischemia 5 | 110
Cardiomyopathies 5 | 110
Chronic gastritis 5 | 5
Chronic obstructive lung disease 5 | 6
Dementia 5 | 175
Diabetes Mellitus, Experimental 5 | 108
Excessive salivation 5 | 5
Gastric ulcer 5 | 33
General anesthesia 5 | 53
Major Depressive Disorder 5 | 301
Obesity 5 | 678
Peptic Ulcer 5 | 27
Toxic encephalopathy 5 | 141
Trigeminal Neuralgia 5 | 24
Urinary Incontinence 5 | 50
Vagal Reflex Bradycardia 5 | 5
Vascular disease 5 | 319
active Crohn's disease 5 | 922
aldosterone-producing adenoma 5 | 665
colon cancer 5 | 1,478
juvenile dermatomyositis 5 | 1,187
posterior fossa group A ependymoma 5 | 468
Angina Pectoris 4 | 32
Arthritis 4 | 290
Autistic Disorder 4 | 364
Cholestasis, Extrahepatic 4 | 25
Heart disease 4 | 306
Hypertensive disorder 4 | 56
Liver Cirrhosis, Experimental 4 | 769
Liver cancer 4 | 604
Mood Disorders 4 | 184
Nerve Degeneration 4 | 121
Prinzmetal angina 4 | 6
Seizures 4 | 596
Skin cancer 4 | 469
Stomach Neoplasms 4 | 300
Syncope 4 | 22
active ulcerative colitis 4 | 764
adrenocortical carcinoma 4 | 1,428
atypical teratoid/rhabdoid tumor 4 | 357
dermatomyositis 4 | 966
acute quadriplegic myopathy 3 | 1,158

Tissue

Digestive Tract 63 | 17,369
Endocrine System 63 | 18,159
Female tissues 63 | 17,400
Nervous System 63 | 16,725
Skin and soft tissues 63 | 17,230
Blood and immune system 62 | 16,909
Liver and Pancreas 62 | 16,750
Male tissues 62 | 17,142
Respiratory system 62 | 16,393
Urinary Tract 61 | 16,678
Cardiovascular System 56 | 15,192

Target Family

Kinase 25 | 634
Enzyme 15 | 4,145
Non-IDG 10 | 12,091
Ion Channel 7 | 344
GPCR 5 | 408
Epigenetic 1 | 242

PathwayCommons: panther Pathway

http://identifiers.org/panther... 63 | 63
http://identifiers.org/panther... 264 | 264
http://identifiers.org/panther... 197 | 197
http://identifiers.org/panther... 164 | 164
http://identifiers.org/panther... 151 | 151
http://identifiers.org/panther... 150 | 150
http://identifiers.org/panther... 149 | 149
http://identifiers.org/panther... 146 | 146
http://identifiers.org/panther... 124 | 124
http://identifiers.org/panther... 118 | 118
http://identifiers.org/panther... 116 | 116
http://identifiers.org/panther... 115 | 115
http://identifiers.org/panther... 110 | 110
http://identifiers.org/panther... 107 | 107
http://identifiers.org/panther... 104 | 104
http://identifiers.org/panther... 91 | 91
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 86 | 86
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 67 | 67
http://identifiers.org/panther... 65 | 65
http://identifiers.org/panther... 61 | 61
http://identifiers.org/panther... 60 | 60
http://identifiers.org/panther... 56 | 56
http://identifiers.org/panther... 54 | 54
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 51 | 51
http://identifiers.org/panther... 47 | 47
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 44 | 44
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 41 | 41
http://identifiers.org/panther... 38 | 38
http://identifiers.org/panther... 37 | 37
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 33 | 33
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 31 | 31
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 27 | 27
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 17 | 17
http://identifiers.org/panther... 16 | 16
http://identifiers.org/panther... 15 | 15
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 13 | 13
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 8 | 8
http://identifiers.org/panther... 8 | 8

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Beta-secretase 2 BACE2 Tchem Enzyme -2.09709 114.0 418
Neuroendocrine convertase 2 PCSK2 Tchem Enzyme -2.00248 109.8 132
CHRNA7-FAM7A fusion protein CHRFAM7A Tbio Non-IDG -1.79939 87.7 87
Disintegrin and metalloproteinase domain-containing protein 9 ADAM9 Tchem Enzyme -2.08807 122.3 258
Protein kinase C beta type PRKCB Tchem Kinase -2.00437 93.5 598
Gamma-secretase subunit PEN-2 PSENEN Tchem Enzyme -2.84761 677.3 204
Protein kinase C gamma type PRKCG Tchem Kinase -2.04120 103.9 435
Muscarinic acetylcholine receptor M5 CHRM5 Tclin GPCR -1.35374 22.9 141
Presenilin-1 PSEN1 Tchem Enzyme -3.53128 3394.7 677
Kinesin light chain 3 KLC3 Tbio Non-IDG -1.01551 11.4 98