Development Level

Tbio 13 | 11,445
Tclin 6 | 613
Tchem 4 | 1,598

IMPC Phenotype

abnormal behavior 2 | 298
decreased prepulse inhibition 2 | 82
decreased total body fat amoun... 2 | 207
embryonic lethality prior to t... 2 | 278
preweaning lethality, incomple... 2 | 499
abnormal embryo size 1 | 220
abnormal gait 1 | 69
abnormal gallbladder morpholog... 1 | 1
abnormal locomotor behavior 1 | 24
abnormal vocalization 1 | 21
decreased body weight 1 | 161
decreased circulating amylase ... 1 | 28
decreased circulating insulin ... 1 | 76
decreased circulating phosphat... 1 | 27
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged gallbladder 1 | 2
hydrometra 1 | 53
hyperactivity 1 | 148
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased circulating calcium ... 1 | 34
increased fasted circulating g... 1 | 76
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 36
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
male infertility 1 | 123
preweaning lethality, complete... 1 | 979
short tibia 1 | 97
small epididymis 1 | 3
small superior vagus ganglion 1 | 74
vertebral fusion 1 | 23

Disease

psoriasis 19 | 6,694
Carcinoma 14 | 11,493
glioblastoma 14 | 5,792
medulloblastoma, large-cell 14 | 6,241
ependymoma 13 | 4,679
Astrocytoma, Pilocytic 12 | 3,081
adult high grade glioma 12 | 3,801
atypical teratoid / rhabdoid tumor 12 | 5,112
lung cancer 12 | 4,740
ovarian cancer 12 | 8,520
group 3 medulloblastoma 10 | 4,104
osteosarcoma 10 | 7,950
primitive neuroectodermal tumor 10 | 3,035
oligodendroglioma 9 | 2,850
Schizophrenia 8 | 1,160
lung carcinoma 8 | 2,843
Bipolar Disorder 7 | 666
lung adenocarcinoma 7 | 2,716
malignant mesothelioma 7 | 3,232
subependymal giant cell astrocytoma 7 | 2,287
Attention deficit hyperactivity disorder 6 | 278
Bronchiectasis 6 | 64
Parkinson's disease 6 | 392
Peripheral vascular disease 6 | 87
astrocytic glioma 6 | 2,597
invasive ductal carcinoma 6 | 2,951
Acute exacerbation of asthma 5 | 14
Administration of Local Anesthetic Nerve Block 5 | 14
Allergic Reactions 5 | 7
Asthma 5 | 385
Asthma management 5 | 19
Autosomal recessive predisposition 5 | 1,442
Breast cancer 5 | 3,578
Bronchitis 5 | 43
Cerebral Ischemia 5 | 37
Dermal Necrosis 5 | 6
Diabetes Mellitus, Experimental 5 | 108
Diagnostic Test for Pheochromocytoma 5 | 6
Dyspnea 5 | 76
Exacerbation of asthma 5 | 11
Hypertension Secondary to Pheochromocytoma 5 | 6
Hypertensive Emergencies 5 | 10
Hypertensive disorder 5 | 56
Kidney cancer 5 | 2,613
Local anesthesia, by infiltration 5 | 14
Low blood pressure 5 | 9
Nasal congestion 5 | 21
Nasal discharge 5 | 24
Open-angle glaucoma 5 | 27
Orthostatic hypotension 5 | 9
Paroxysmal hypertension 5 | 6
Pheochromocytoma 5 | 24
Prevention of Hypertension in Pheochromocytoma 5 | 6
Pulmonary emphysema 5 | 48
Red eye 5 | 7
Tetanus 5 | 68
Wheezing 5 | 7
anaphylaxis 5 | 11
colon cancer 5 | 1,478
interstitial cystitis 5 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
Cancer 4 | 2,499
Cardiomegaly 4 | 116
Cerebrovascular disease 4 | 238
Depressive disorder 4 | 409
Disorder of blood vessel 4 | 4
Intellectual disability 4 | 1,016
Persistent pulmonary hypertension of the newborn 4 | 8
Pick disease 4 | 1,894
astrocytoma 4 | 1,146
cystic fibrosis 4 | 1,696
group 4 medulloblastoma 4 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
non-small cell lung cancer 4 | 2,890
ulcerative colitis 4 | 1,819
Actinic keratosis 3 | 21
Botulism 3 | 24
Conscious sedation 3 | 10
Dysarthria 3 | 192
Epilepsy 3 | 792
Essential Hypertension 3 | 94
Gaucher disease type 1 3 | 180
Hyperreflexia 3 | 209
Hypertension 3 | 396
Hypotension 3 | 82
Liver Cirrhosis, Experimental 3 | 769
Liver cancer 3 | 604
Major Depressive Disorder 3 | 301
Melanoma 3 | 711
Mood Disorders 3 | 184
Neurodegenerative disease 3 | 414
Ocular hypertension 3 | 42
Prevention of Cerebral Thrombosis 3 | 29
Rosacea 3 | 25
Spasticity 3 | 26
Unipolar Depression 3 | 250
adrenocortical carcinoma 3 | 1,428
spina bifida 3 | 1,074
tuberculosis 3 | 2,010

Tissue

Blood and immune system 23 | 16,909
Digestive Tract 23 | 17,369
Endocrine System 23 | 18,159
Female tissues 23 | 17,400
Liver and Pancreas 23 | 16,750
Male tissues 23 | 17,142
Nervous System 23 | 16,725
Skin and soft tissues 23 | 17,230
Cardiovascular System 22 | 15,192
Respiratory system 22 | 16,393
Urinary Tract 22 | 16,678

Target Family

Non-IDG 8 | 12,091
Enzyme 5 | 4,145
GPCR 5 | 408
Kinase 4 | 634
Ion Channel 1 | 344

PathwayCommons: panther Pathway

http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 264 | 264
http://identifiers.org/panther... 197 | 197
http://identifiers.org/panther... 164 | 164
http://identifiers.org/panther... 151 | 151
http://identifiers.org/panther... 150 | 150
http://identifiers.org/panther... 149 | 149
http://identifiers.org/panther... 146 | 146
http://identifiers.org/panther... 124 | 124
http://identifiers.org/panther... 118 | 118
http://identifiers.org/panther... 116 | 116
http://identifiers.org/panther... 115 | 115
http://identifiers.org/panther... 110 | 110
http://identifiers.org/panther... 107 | 107
http://identifiers.org/panther... 104 | 104
http://identifiers.org/panther... 91 | 91
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 88 | 88
http://identifiers.org/panther... 86 | 86
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 70 | 70
http://identifiers.org/panther... 67 | 67
http://identifiers.org/panther... 65 | 65
http://identifiers.org/panther... 63 | 63
http://identifiers.org/panther... 61 | 61
http://identifiers.org/panther... 60 | 60
http://identifiers.org/panther... 56 | 56
http://identifiers.org/panther... 54 | 54
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 53 | 53
http://identifiers.org/panther... 51 | 51
http://identifiers.org/panther... 47 | 47
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 46 | 46
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 45 | 45
http://identifiers.org/panther... 44 | 44
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 43 | 43
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 42 | 42
http://identifiers.org/panther... 41 | 41
http://identifiers.org/panther... 38 | 38
http://identifiers.org/panther... 37 | 37
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 35 | 35
http://identifiers.org/panther... 33 | 33
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 32 | 32
http://identifiers.org/panther... 31 | 31
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 30 | 30
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 29 | 29
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 28 | 28
http://identifiers.org/panther... 27 | 27
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 26 | 26
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 24 | 24
http://identifiers.org/panther... 23 | 23
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 21 | 21
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 19 | 19
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 18 | 18
http://identifiers.org/panther... 17 | 17
http://identifiers.org/panther... 16 | 16
http://identifiers.org/panther... 15 | 15
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 14 | 14
http://identifiers.org/panther... 13 | 13
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 12 | 12
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 11 | 11
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 10 | 10
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 9 | 9
http://identifiers.org/panther... 8 | 8
http://identifiers.org/panther... 8 | 8

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Guanine nucleotide-binding protein subunit alpha-11 GNA11 Tbio Non-IDG -2.80484 555.1 184
Alpha-1B adrenergic receptor ADRA1B Tclin GPCR -2.30594 201.5 364
Alpha-1A adrenergic receptor ADRA1A Tclin GPCR -2.18682 155.5 236
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 PLCB2 Tbio Enzyme -2.14048 137.8 104
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 PLCB3 Tbio Enzyme -1.88444 66.2 265
Alpha-2A adrenergic receptor ADRA2A Tclin GPCR -2.42160 261.4 232
Syntaxin-10 STX10 Tbio Non-IDG -1.14573 14.1 92
Protein kinase C gamma type PRKCG Tchem Kinase -2.04120 103.9 435
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 PLCE1 Tbio Enzyme -1.96455 94.9 28
Alpha-2B adrenergic receptor ADRA2B Tclin GPCR -2.15839 139.8 0