Development Level

Tbio 39 | 11,445
Tchem 23 | 1,598
Tclin 12 | 613

Collection

Ion Channel: IDG Consortium (T... 1 | 99
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 5 | 979
preweaning lethality, incomple... 4 | 499
abnormal retina morphology 2 | 71
abnormal skin morphology 2 | 50
decreased circulating creatini... 2 | 39
increased mean corpuscular hem... 2 | 96
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal femur morphology 1 | 14
abnormal tooth morphology 1 | 24
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating sodium l... 1 | 22
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased neutrophil cell numb... 1 | 42
edema 1 | 59
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
hydrometra 1 | 53
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased blood uric acid leve... 1 | 5
increased circulating LDL chol... 1 | 13
increased circulating chloride... 1 | 41
increased circulating triglyce... 1 | 42
increased granulocyte number 1 | 1
increased hemoglobin content 1 | 45
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
persistence of hyaloid vascula... 1 | 33
short tibia 1 | 97
small superior vagus ganglion 1 | 74

Disease

Carcinoma 59 | 11,493
ovarian cancer 51 | 8,520
Cancer 48 | 2,499
glioblastoma 40 | 5,792
osteosarcoma 39 | 7,950
Breast cancer 37 | 3,578
atypical teratoid / rhabdoid tumor 36 | 5,112
lung cancer 36 | 4,740
Kidney cancer 34 | 2,613
medulloblastoma, large-cell 34 | 6,241
psoriasis 34 | 6,694
ependymoma 30 | 4,679
malignant mesothelioma 29 | 3,232
pancreatic cancer 29 | 2,398
non-small cell lung cancer 26 | 2,890
intraductal papillary-mucinous neoplasm (IPMN) 23 | 3,291
invasive ductal carcinoma 23 | 2,951
intraductal papillary-mucinous adenoma (IPMA) 22 | 2,955
Astrocytoma, Pilocytic 21 | 3,081
adult high grade glioma 21 | 3,801
lung carcinoma 21 | 2,843
Schizophrenia 20 | 1,160
Autosomal recessive predisposition 19 | 1,442
breast carcinoma 19 | 1,638
diabetes mellitus 19 | 1,728
group 3 medulloblastoma 19 | 4,104
group 4 medulloblastoma 19 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,989
lung adenocarcinoma 19 | 2,716
oligodendroglioma 19 | 2,850
interstitial cystitis 18 | 2,312
primitive neuroectodermal tumor 18 | 3,035
juvenile dermatomyositis 17 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 17 | 1,962
subependymal giant cell astrocytoma 17 | 2,287
cystic fibrosis 15 | 1,696
astrocytic glioma 14 | 2,597
astrocytoma 14 | 1,146
ductal carcinoma in situ 14 | 1,745
primary pancreatic ductal adenocarcinoma 14 | 1,109
Breast Neoplasms 13 | 445
Waldenstrons macroglobulinemia 13 | 765
dermatomyositis 13 | 966
Carcinoma, Hepatocellular 12 | 228
Liver carcinoma 12 | 240
Lung Neoplasms 12 | 232
Mammary Neoplasms 12 | 425
Prostatic Neoplasms 12 | 495
Rheumatoid arthritis 12 | 1,191
Stomach Neoplasms 12 | 300
tuberculosis 12 | 2,010
Heart disease 11 | 306
Liver cancer 11 | 604
Parkinson's disease 11 | 392
acute quadriplegic myopathy 11 | 1,158
colon cancer 11 | 1,478
pituitary cancer 11 | 1,972
ulcerative colitis 11 | 1,819
Alzheimer's disease 10 | 658
Epidermolysis bullosa 10 | 21
Hypertension 10 | 396
Kidney disease 10 | 430
Multiple myeloma 10 | 1,332
Neoplasm Invasiveness 10 | 161
Pick disease 10 | 1,894
Renal Cell Carcinoma 10 | 214
Vascular disease 10 | 319
esophageal adenocarcinoma 10 | 737
Arthritis 9 | 290
Carcinoma, Squamous Cell 9 | 110
Down syndrome 9 | 499
Dystrophia unguium 9 | 53
Failure to gain weight 9 | 365
Neoplasm Metastasis 9 | 168
Pediatric failure to thrive 9 | 365
Squamous cell carcinoma 9 | 129
ANONYCHIA 8 | 20
Anemia 8 | 365
Atrophic scar 8 | 18
Disease Models, Animal 8 | 155
Epilepsy 8 | 792
Hyperglycemia 8 | 137
Myopia 8 | 176
Nail dysplasia 8 | 52
Obesity 8 | 678
Oral mucosal blistering 8 | 10
Ovarian Neoplasms 8 | 102
Seizures 8 | 596
Skin cancer 8 | 469
cutaneous lupus erythematosus 8 | 1,057
medulloblastoma 8 | 720
Asthma 7 | 385
Death in early childhood 7 | 82
Lung disease 7 | 142
Melanoma 7 | 711
Prenatal onset 7 | 139
active ulcerative colitis 7 | 764
nasopharyngeal carcinoma 7 | 1,058
pediatric high grade glioma 7 | 1,064
progressive supranuclear palsy 7 | 676

Tissue

Blood and immune system 74 | 16,909
Digestive Tract 74 | 17,369
Endocrine System 74 | 18,159
Female tissues 74 | 17,400
Liver and Pancreas 74 | 16,750
Male tissues 74 | 17,142
Nervous System 74 | 16,725
Skin and soft tissues 74 | 17,230
Urinary Tract 74 | 16,678
Respiratory system 73 | 16,393
Cardiovascular System 69 | 15,192

Target Family

Non-IDG 36 | 12,091
Kinase 24 | 634
Enzyme 6 | 4,145
Transcription Factor 5 | 1,400
Ion Channel 2 | 344
Nuclear Receptor 1 | 48

PathwayCommons: netpath Pathway

http://pathwaycommons.org/pc2/... 74 | 74
http://pathwaycommons.org/pc2/... 472 | 472
http://pathwaycommons.org/pc2/... 270 | 270
http://pathwaycommons.org/pc2/... 258 | 258
http://pathwaycommons.org/pc2/... 220 | 220
http://pathwaycommons.org/pc2/... 164 | 164
http://pathwaycommons.org/pc2/... 161 | 161
http://pathwaycommons.org/pc2/... 118 | 118
http://pathwaycommons.org/pc2/... 104 | 104
http://pathwaycommons.org/pc2/... 104 | 104
http://pathwaycommons.org/pc2/... 98 | 98
http://pathwaycommons.org/pc2/... 85 | 85
http://pathwaycommons.org/pc2/... 84 | 84
http://pathwaycommons.org/pc2/... 84 | 84
http://pathwaycommons.org/pc2/... 81 | 81
http://pathwaycommons.org/pc2/... 81 | 81
http://pathwaycommons.org/pc2/... 76 | 76
http://pathwaycommons.org/pc2/... 73 | 73
http://pathwaycommons.org/pc2/... 69 | 69
http://pathwaycommons.org/pc2/... 59 | 59
http://pathwaycommons.org/pc2/... 44 | 44
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 35 | 35
http://pathwaycommons.org/pc2/... 28 | 28
http://pathwaycommons.org/pc2/... 24 | 24
http://pathwaycommons.org/pc2/... 24 | 24

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Rhotekin RTKN Tbio Non-IDG -1.49615 24.3 137
14-3-3 protein theta YWHAQ Tchem Non-IDG -2.43493 235.4 358
GRB2-associated-binding protein 1 GAB1 Tbio Non-IDG -1.55563 50.4 268
Collagen alpha-1(XVII) chain COL17A1 Tbio Non-IDG -2.75473 576.3 123
Laminin subunit gamma-1 LAMC1 Tbio Non-IDG -1.79184 56.7 318
CD151 antigen CD151 Tbio Non-IDG -2.40013 244.5 420
Tumor protein p73 TP73 Tbio Transcription Factor -1.92832 82.6 708
Desmoplakin DSP Tbio Non-IDG -2.95735 853.9 198
Bcl2-associated agonist of cell death BAD Tchem Non-IDG -2.08893 103.4 2565
Hepatocyte growth factor receptor MET Tclin Kinase -3.32232 2013.7 1982