Development Level

Tchem 15 | 1,598
Tbio 7 | 11,445
Tclin 2 | 613

IMPC Phenotype

abnormal cornea morphology 1 | 31
abnormal gait 1 | 69
abnormal skin condition 1 | 6
decreased circulating amylase ... 1 | 28
decreased circulating sodium l... 1 | 22
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased thermal nociceptive ... 1 | 2
enlarged lymph nodes 1 | 37
impaired righting response 1 | 26
increased circulating alkaline... 1 | 122
increased circulating free fat... 1 | 20
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased neutrophil cell numb... 1 | 46
increased thermal nociceptive ... 1 | 9
preweaning lethality, complete... 1 | 979

Disease

Cancer 21 | 2,499
Carcinoma 17 | 11,493
lung cancer 15 | 4,740
ovarian cancer 14 | 8,520
osteosarcoma 13 | 7,950
atypical teratoid / rhabdoid tumor 11 | 5,112
glioblastoma 11 | 5,792
psoriasis 11 | 6,694
Arthritis 10 | 290
Asthma 10 | 385
medulloblastoma, large-cell 10 | 6,241
Breast cancer 9 | 3,578
tuberculosis 9 | 2,010
Inflammatory bowel disease 8 | 151
Vascular disease 8 | 319
adult high grade glioma 8 | 3,801
ependymoma 8 | 4,679
malignant mesothelioma 8 | 3,232
Astrocytoma, Pilocytic 7 | 3,081
Atopic dermatitis 7 | 952
Brain Ischemia 7 | 110
Lung disease 7 | 142
Rheumatoid arthritis 7 | 1,191
Schizophrenia 7 | 1,160
Anemia 6 | 365
Breast Neoplasms 6 | 445
Disease Models, Animal 6 | 155
Mammary Neoplasms 6 | 425
Multiple Sclerosis 6 | 540
Multiple myeloma 6 | 1,332
Precancerous Conditions 6 | 80
Stomach Neoplasms 6 | 300
group 3 medulloblastoma 6 | 4,104
group 4 medulloblastoma 6 | 1,855
Alzheimer's disease 5 | 658
Cardiomyopathies 5 | 110
Cell Transformation, Neoplastic 5 | 97
Cholestasis, Extrahepatic 5 | 25
Inflammation 5 | 120
Kidney cancer 5 | 2,613
Lung Neoplasms 5 | 232
Neoplasm Metastasis 5 | 168
Neoplastic Cell Transformation 5 | 89
Obesity 5 | 678
Splenomegaly 5 | 190
cystic fibrosis 5 | 1,696
diabetes mellitus 5 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
invasive ductal carcinoma 5 | 2,951
lung adenocarcinoma 5 | 2,716
lung carcinoma 5 | 2,843
pituitary cancer 5 | 1,972
primitive neuroectodermal tumor 5 | 3,035
subependymal giant cell astrocytoma 5 | 2,287
ulcerative colitis 5 | 1,819
Carcinoma, Hepatocellular 4 | 228
Carcinoma, Squamous Cell 4 | 110
Colitis, Ulcerative 4 | 59
Crohn's disease 4 | 321
Depressive disorder 4 | 409
Fever 4 | 138
Heart disease 4 | 306
Heat Stroke 4 | 13
Hyperalgesia 4 | 83
Hypersensitivity reaction type II disease 4 | 253
Immune system cancer 4 | 140
Kidney disease 4 | 430
Liver Cirrhosis, Experimental 4 | 769
Liver Neoplasms, Experimental 4 | 59
Liver carcinoma 4 | 240
Lymphoid leukemia 4 | 160
Lymphopenia 4 | 67
Myocardial Ischemia 4 | 169
Ovarian Neoplasms 4 | 102
Pick disease 4 | 1,894
Pneumonia 4 | 174
Polycythemia vera 4 | 27
Prostatic Neoplasms 4 | 495
Recurrent respiratory infections 4 | 141
Reperfusion Injury 4 | 86
Squamous cell carcinoma 4 | 129
Trigeminal Neuralgia 4 | 24
astrocytoma 4 | 1,146
ductal carcinoma in situ 4 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
non-small cell lung cancer 4 | 2,890
oligodendroglioma 4 | 2,850
ovarian neoplasm 4 | 99
pancreatic cancer 4 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
primary Sjogren syndrome 4 | 735
Allergic hypersensitivity disease 3 | 126
Dermatitis, Atopic 3 | 37
Eye disease 3 | 62
Hypereosinophilic syndrome 3 | 71
Mastocytosis 3 | 27
Mental Depression 3 | 333
Parkinson's disease 3 | 392
adrenocortical carcinoma 3 | 1,428
colon cancer 3 | 1,478

Tissue

Blood and immune system 24 | 16,909
Digestive Tract 24 | 17,369
Endocrine System 24 | 18,159
Female tissues 24 | 17,400
Liver and Pancreas 24 | 16,750
Male tissues 24 | 17,142
Respiratory system 24 | 16,393
Skin and soft tissues 24 | 17,230
Urinary Tract 24 | 16,678
Cardiovascular System 23 | 15,192
Nervous System 23 | 16,725

Target Family

Transcription Factor 10 | 1,400
Kinase 8 | 634
Non-IDG 6 | 12,091

PathwayCommons: netpath Pathway

http://pathwaycommons.org/pc2/... 24 | 24
http://pathwaycommons.org/pc2/... 472 | 472
http://pathwaycommons.org/pc2/... 270 | 270
http://pathwaycommons.org/pc2/... 258 | 258
http://pathwaycommons.org/pc2/... 220 | 220
http://pathwaycommons.org/pc2/... 164 | 164
http://pathwaycommons.org/pc2/... 161 | 161
http://pathwaycommons.org/pc2/... 118 | 118
http://pathwaycommons.org/pc2/... 104 | 104
http://pathwaycommons.org/pc2/... 104 | 104
http://pathwaycommons.org/pc2/... 98 | 98
http://pathwaycommons.org/pc2/... 85 | 85
http://pathwaycommons.org/pc2/... 84 | 84
http://pathwaycommons.org/pc2/... 84 | 84
http://pathwaycommons.org/pc2/... 81 | 81
http://pathwaycommons.org/pc2/... 81 | 81
http://pathwaycommons.org/pc2/... 76 | 76
http://pathwaycommons.org/pc2/... 74 | 74
http://pathwaycommons.org/pc2/... 73 | 73
http://pathwaycommons.org/pc2/... 69 | 69
http://pathwaycommons.org/pc2/... 59 | 59
http://pathwaycommons.org/pc2/... 44 | 44
http://pathwaycommons.org/pc2/... 39 | 39
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 35 | 35
http://pathwaycommons.org/pc2/... 28 | 28
http://pathwaycommons.org/pc2/... 24 | 24

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cytokine receptor-like factor 2 CRLF2 Tbio Non-IDG -1.91113 78.7 393
40S ribosomal protein S6 RPS6 Tbio Non-IDG -2.76789 501.6 920
Thymic stromal lymphopoietin TSLP Tbio Non-IDG -2.78236 713.0 495
Signal transducer and activator of transcription 4 STAT4 Tbio Transcription Factor -2.51382 320.4 790
Mitogen-activated protein kinase 1 MAPK1 Tchem Kinase -3.18822 1239.4 1248
Eukaryotic translation initiation factor 4E-binding protein 1 EIF4EBP1 Tbio Non-IDG -2.83637 578.9 1455
Mitogen-activated protein kinase 3 MAPK3 Tchem Kinase -3.66226 3484.0 1440
Interleukin-7 receptor subunit alpha IL7R Tbio Non-IDG -2.77688 547.0 828
Nuclear factor NF-kappa-B p100 subunit NFKB2 Tchem Transcription Factor -2.29577 191.3 637
NF-kappa-B inhibitor alpha NFKBIA Tchem Non-IDG -3.34987 1979.8 1300