Development Level

Tchem 17 | 1,890
Tbio 5 | 10,625
Tclin 2 | 602

IMPC Phenotype

decreased lean body mass 2 | 195
abnormal coping response 1 | 12
abnormal cornea morphology 1 | 24
abnormal skin condition 1 | 6
decreased bone mineral content 1 | 157
decreased circulating amylase ... 1 | 24
decreased circulating sodium l... 1 | 18
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular hem... 1 | 19
decreased mean corpuscular vol... 1 | 50
decreased thermal nociceptive ... 1 | 4
enlarged lymph nodes 1 | 27
increased circulating alkaline... 1 | 119
increased circulating free fat... 1 | 17
increased lean body mass 1 | 107
increased leukocyte cell numbe... 1 | 37
increased thermal nociceptive ... 1 | 9

Disease

Cancer 21 | 2,346
ovarian cancer 14 | 8,491
lung cancer 13 | 4,473
osteosarcoma 13 | 7,933
glioblastoma 11 | 5,572
psoriasis 11 | 6,685
atypical teratoid / rhabdoid tumor 10 | 4,369
medulloblastoma, large-cell 10 | 6,234
Arthritis 9 | 248
Asthma 9 | 349
Breast cancer 9 | 3,098
Vascular disease 8 | 281
malignant mesothelioma 8 | 3,163
tuberculosis 8 | 1,563
Atopic dermatitis 7 | 944
Rheumatoid Arthritis 7 | 1,170
pilocytic astrocytoma 7 | 3,086
ulcerative colitis 7 | 2,087
Brain Ischemia 6 | 87
Inflammatory bowel disease 6 | 142
Lung disease 6 | 136
Mammary Neoplasms 6 | 410
Multiple Sclerosis 6 | 498
Multiple myeloma 6 | 1,327
ependymoma 6 | 2,514
group 4 medulloblastoma 6 | 1,875
pediatric high grade glioma 6 | 2,712
Alzheimer's disease 5 | 644
Carcinoma 5 | 2,147
Cardiomyopathies 5 | 90
Lung Neoplasms 5 | 171
Obesity 5 | 616
Stomach Neoplasms 5 | 282
cystic fibrosis 5 | 1,670
diabetes mellitus 5 | 1,663
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,289
invasive ductal carcinoma 5 | 2,950
lung adenocarcinoma 5 | 2,714
lung carcinoma 5 | 2,844
pituitary cancer 5 | 1,972
primitive neuroectodermal tumor 5 | 3,031
subependymal giant cell astrocytoma 5 | 2,287
Anemia 4 | 252
Crohn's disease 4 | 304
Heart disease 4 | 279
Heat Stroke 4 | 12
Kidney disease 4 | 397
Liver carcinoma 4 | 217
Myocardial Ischemia 4 | 169
Neoplasm Metastasis 4 | 138
Neoplastic Cell Transformation 4 | 81
Pick disease 4 | 1,893
Polycythemia Vera 4 | 24
Prostatic Neoplasms 4 | 471
Reperfusion Injury 4 | 84
Squamous cell carcinoma 4 | 96
astrocytoma 4 | 1,493
ductal carcinoma in situ 4 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,988
medulloblastoma 4 | 1,524
oligodendroglioma 4 | 2,849
ovarian neoplasm 4 | 97
pancreatic cancer 4 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
primary Sjogren syndrome 4 | 788
Adenocarcinoma 3 | 115
Biliary cirrhosis 3 | 33
Brain disease 3 | 84
Colonic Neoplasms 3 | 126
Dermatitis, Atopic 3 | 45
Eye disease 3 | 55
Head and Neck Neoplasms 3 | 23
Hemorrhagic disease 3 | 11
Hypersensitivity reaction type II disease 3 | 235
Kidney Neoplasm 3 | 27
Leukemia, Myelocytic, Acute 3 | 113
Mantle cell lymphoma 3 | 20
Mastocytosis 3 | 27
Neoplasm Invasiveness 3 | 127
Parkinson's disease 3 | 364
Precancerous Conditions 3 | 69
Primary polycythemia 3 | 7
Severe Combined Immunodeficiency 3 | 46
Toxic encephalopathy 3 | 131
acute myeloid leukemia 3 | 785
adrenocortical carcinoma 3 | 1,427
adult high grade glioma 3 | 2,148
astrocytic glioma 3 | 2,241
colon cancer 3 | 1,475
cutaneous lupus erythematosus 3 | 1,056
dermatomyositis 3 | 966
interstitial cystitis 3 | 2,299
juvenile dermatomyositis 3 | 1,189
non-small cell lung cancer 3 | 2,798
systemic lupus erythematosus 3 | 172
Allergic hypersensitivity disease 2 | 123
Allergic rhinitis 2 | 92
Eosinophilia 2 | 65
Parasitic helminthiasis infectious disease 2 | 13
progressive supranuclear palsy 2 | 674

Tissue

Blood and immune system 24 | 17,994
Cardiovascular System 24 | 17,957
Digestive Tract 24 | 18,472
Endocrine System 24 | 18,511
Female tissues 24 | 18,646
Liver and Pancreas 24 | 18,135
Male tissues 24 | 17,968
Nervous System 24 | 18,560
Respiratory system 24 | 17,483
Skin and soft tissues 24 | 18,114
Urinary Tract 24 | 18,443

Target Family

Transcription Factor 10 | 1,400
Kinase 8 | 634
Non-IDG 6 | 11,969

PathwayCommons: netpath Pathway

TSLP 24 | 24
EGFR1 473 | 473
TNFalpha 271 | 271
TCR 259 | 259
TGF_beta_Receptor 220 | 220
AndrogenReceptor 164 | 164
BCR 161 | 161
Wnt 118 | 118
Prolactin 105 | 105
KitReceptor 104 | 104
Leptin 98 | 98
IL6 85 | 85
IL3 84 | 84
RANKL 84 | 84
TSH 82 | 82
IL2 81 | 81
Notch 76 | 76
Alpha6Beta4Integrin 74 | 74
IL4 73 | 73
IL1 69 | 69
IL5 59 | 59
FSH 44 | 44
Hedgehog 39 | 39
ID 38 | 38
TWEAK 35 | 35
IL-7 28 | 28
IL9 24 | 24

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Signal transducer and activator of transcription 3 STAT3 Tchem Transcription Factor -3.75815 5706.6 1539
Interleukin-7 receptor subunit alpha IL7R Tbio Non-IDG -2.76199 528.6 688
Nuclear factor NF-kappa-B p100 subunit NFKB2 Tchem Transcription Factor -2.25781 180.0 594
Signal transducer and activator of transcription 1-alpha/beta STAT1 Tchem Transcription Factor -3.29893 1889.3 1357
Signal transducer and activator of transcription 5A STAT5A Tchem Transcription Factor -3.00212 913.0 1086
Signal transducer and activator of transcription 6 STAT6 Tchem Transcription Factor -2.87815 736.9 910
Tyrosine-protein kinase JAK1 JAK1 Tclin Kinase -2.73793 446.6 400
NF-kappa-B inhibitor alpha NFKBIA Tchem Non-IDG -3.34592 1960.9 1181
Thymic stromal lymphopoietin TSLP Tbio Non-IDG -2.71698 624.2 414
40S ribosomal protein S6 RPS6 Tchem Non-IDG -2.74559 472.5 809