Development Level

Tchem 14 | 1,598
Tclin 2 | 613

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal gait 1 | 69
abnormal lens morphology 1 | 81
decreased body weight 1 | 161
decreased circulating creatini... 1 | 39
decreased total body fat amoun... 1 | 207
embryonic lethality prior to t... 1 | 278
increased erythrocyte cell num... 1 | 39
increased hematocrit 1 | 46

Disease

Carcinoma 14 | 11,493
glioblastoma 12 | 5,792
atypical teratoid / rhabdoid tumor 11 | 5,112
Cancer 10 | 2,499
ovarian cancer 10 | 8,520
osteosarcoma 9 | 7,950
adult high grade glioma 8 | 3,801
lung cancer 8 | 4,740
medulloblastoma, large-cell 8 | 6,241
psoriasis 8 | 6,694
Vascular disease 6 | 319
Astrocytoma, Pilocytic 5 | 3,081
ependymoma 5 | 4,679
group 3 medulloblastoma 5 | 4,104
subependymal giant cell astrocytoma 5 | 2,287
Cholestasis, Extrahepatic 4 | 25
Kidney cancer 4 | 2,613
Schizophrenia 4 | 1,160
diabetes mellitus 4 | 1,728
group 4 medulloblastoma 4 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
primitive neuroectodermal tumor 4 | 3,035
tuberculosis 4 | 2,010
Acquired scoliosis 3 | 281
Alzheimer's disease 3 | 658
Arthritis 3 | 290
Brain Ischemia 3 | 110
Brain disease 3 | 96
Breast cancer 3 | 3,578
Byzanthine arch palate 3 | 194
Cardiofaciocutaneous syndrome 3 | 15
Costello Syndrome 3 | 17
Curvature of spine 3 | 282
Downward slant of palpebral fissure 3 | 158
Dull intelligence 3 | 645
Intellectual disability 3 | 1,016
Low intelligence 3 | 645
Lung Neoplasms 3 | 232
Lung disease 3 | 142
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Noonan syndrome 3 | 34
Orbital separation excessive 3 | 244
Parkinson's disease 3 | 392
Pick disease 3 | 1,894
Poor school performance 3 | 645
Precancerous Conditions 3 | 80
Reperfusion Injury 3 | 86
Short stature 3 | 531
Toxic encephalopathy 3 | 141
acute myeloid leukemia 3 | 783
astrocytic glioma 3 | 2,597
juvenile dermatomyositis 3 | 1,187
non-small cell lung cancer 3 | 2,890
oligodendroglioma 3 | 2,850
pancreatic cancer 3 | 2,398
Absence of eyebrows 2 | 31
Aplasia/Hypoplasia of the eyebrow 2 | 31
Atrial Septal Defects 2 | 85
Big calvaria 2 | 147
Blepharoptosis 2 | 231
Breast Neoplasms 2 | 445
Cardiomyopathies 2 | 110
Cardiomyopathy 2 | 116
Coarse facial features 2 | 108
Disease Models, Animal 2 | 155
Frontal bossing 2 | 157
Hemangioma, Cavernous 2 | 20
High forehead 2 | 102
Hyperalgesia 2 | 83
Hyperhidrosis disorder 2 | 81
Hypertrophic Cardiomyopathy 2 | 117
Ichthyoses 2 | 41
Increased head circumference 2 | 147
Increased size of cranium 2 | 147
Increased size of skull 2 | 147
Increased sweating 2 | 81
Large auricle 2 | 87
Large dysplastic ears 2 | 87
Large pinnae 2 | 87
Large prominent ears 2 | 87
Large protruding ears 2 | 87
Large, floppy ears 2 | 87
Liver disease 2 | 237
Macrotia 2 | 87
Mammary Neoplasms 2 | 425
Premature Birth 2 | 77
Premature birth of newborn 2 | 67
Sensorineural Hearing Loss (disorder) 2 | 284
Skin hyperelastic 2 | 32
Sparse hair 2 | 59
Sparse or absent eyebrows 2 | 31
Sparse/absent eyebrows 2 | 31
Sweating 2 | 81
Tall forehead 2 | 102
Thickened facial skin with coarse facial features 2 | 108
Thin, sparse hair 2 | 59
Underdeveloped brows 2 | 38
Underdeveloped supraorbital ridges 2 | 38

Tissue

Blood and immune system 16 | 16,909
Cardiovascular System 16 | 15,192
Digestive Tract 16 | 17,369
Endocrine System 16 | 18,159
Female tissues 16 | 17,400
Liver and Pancreas 16 | 16,750
Male tissues 16 | 17,142
Nervous System 16 | 16,725
Respiratory system 16 | 16,393
Skin and soft tissues 16 | 17,230
Urinary Tract 16 | 16,678

Target Family

Kinase 15 | 634
Transcription Factor 1 | 1,400

PathwayCommons: inoh Pathway

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