Development Level

Tbio 5 | 11,445
Tchem 1 | 1,598
Tclin 1 | 613

IMPC Phenotype

abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal lens morphology 1 | 81
abnormal response to tactile s... 1 | 17
abnormal skin morphology 1 | 50
abnormal startle reflex 1 | 15
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased hemoglobin content 1 | 68
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
hypoactivity 1 | 132
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134

Disease

Carcinoma 6 | 11,493
Succinic semialdehyde dehydrogenase deficiency 5 | 16
lung cancer 5 | 4,740
psoriasis 5 | 6,694
acute myeloid leukemia 4 | 783
breast carcinoma 4 | 1,638
ductal carcinoma in situ 4 | 1,745
invasive ductal carcinoma 4 | 2,951
medulloblastoma, large-cell 4 | 6,241
ovarian cancer 4 | 8,520
Alcohol dependence 3 | 107
Atopic dermatitis 3 | 952
Cancer 3 | 2,499
Liver Cirrhosis, Experimental 3 | 769
ependymoma 3 | 4,679
group 3 medulloblastoma 3 | 4,104
pituitary cancer 3 | 1,972
Alcohol abuse 2 | 50
Alcoholic Intoxication 2 | 34
Alcoholic Intoxication, Chronic 2 | 289
Asthma 2 | 385
Autosomal recessive predisposition 2 | 1,442
Breast cancer 2 | 3,578
Dull intelligence 2 | 645
Epilepsy 2 | 792
Flushing 2 | 60
Intellectual disability 2 | 1,016
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Myopia 2 | 176
Parkinsonian Disorders 2 | 56
Poor school performance 2 | 645
Schizophrenia 2 | 1,160
adrenocortical carcinoma 2 | 1,428
adult high grade glioma 2 | 3,801
atypical teratoid / rhabdoid tumor 2 | 5,112
colon cancer 2 | 1,478
cystic fibrosis 2 | 1,696
esophageal adenocarcinoma 2 | 737
fibroadenoma 2 | 559
glioblastoma 2 | 5,792
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
lung adenocarcinoma 2 | 2,716
non-small cell lung cancer 2 | 2,890
osteosarcoma 2 | 7,950
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
primitive neuroectodermal tumor 2 | 3,035
tuberculosis 2 | 2,010
Abnormal skeletal development 1 | 60
Abnormality of metabolism/homeostasis 1 | 134
Abnormality of retinal pigmentation 1 | 111
Carcinoma, Renal Cell 1 | 124
Central nervous system demyelination 1 | 28
Cerebral palsy 1 | 40
Colorectal Neoplasms 1 | 243
Congenital diaphragmatic hernia 1 | 67
Creutzfeldt-Jakob Syndrome 1 | 10
Creutzfeldt-Jakob disease 1 | 21
Cyclothymic disorder 1 | 8
Defective enamel matrix 1 | 35
Dental Enamel Hypoplasia 1 | 43
DiGeorge syndrome 1 | 47
Dry skin 1 | 75
Dysplasia of tooth enamel 1 | 35
Epilepsies, Myoclonic 1 | 32
Erythema 1 | 58
Esophageal Neoplasms 1 | 69
Esophageal Squamous Cell Carcinoma 1 | 77
Gaucher disease type 1 1 | 180
Generalized myoclonic seizures 1 | 30
Heroin dependence 1 | 30
Hyperkeratosis 1 | 50
Ichthyoses 1 | 41
Ichthyosis 1 | 56
Impotence 1 | 42
Intracranial aneurysm 1 | 24
Liver disease 1 | 237
Macular degeneration 1 | 65
Matthew-Wood syndrome 1 | 11
Meningomyelocele 1 | 6
Myoclonic Epilepsies, Progressive 1 | 44
Osteochondrodysplasias 1 | 72
Osteoporosis 1 | 363
Photodysphoria 1 | 121
Photophobia 1 | 121
Premature ejaculation 1 | 16
Pseudoxanthoma elasticum 1 | 18
Quadriplegia 1 | 20
Renal Cell Carcinoma 1 | 214
Respiratory distress 1 | 43
Retinal pigment epithelial abnormality 1 | 111
Sengers syndrome 1 | 18
Squamous cell carcinoma of esophagus 1 | 77
Thin dental enamel 1 | 35
Vascular Diseases 1 | 16
X-linked cerebral adrenoleukodystrophy 1 | 116
Xerosis 1 | 75
limb girdle muscular dystrophy 2B 1 | 40

Tissue

Blood and immune system 7 | 16,909
Cardiovascular System 7 | 15,192
Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Female tissues 7 | 17,400
Liver and Pancreas 7 | 16,750
Male tissues 7 | 17,142
Nervous System 7 | 16,725
Respiratory system 7 | 16,393
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678

Target Family

Enzyme 7 | 4,145

PathwayCommons: inoh Pathway

http://pathwaycommons.org/pc2/... 7 | 7
http://pathwaycommons.org/pc2/... 236 | 236
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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
4-trimethylaminobutyraldehyde dehydrogenase ALDH9A1 Tbio Enzyme -1.43954 27.0 162
Alpha-aminoadipic semialdehyde dehydrogenase ALDH7A1 Tbio Enzyme -3.14670 1303.9 150
Retinal dehydrogenase 2 ALDH1A2 Tbio Enzyme -2.25078 175.3 229
Retinal dehydrogenase 1 ALDH1A1 Tchem Enzyme -2.81062 648.3 725
Aldehyde dehydrogenase X, mitochondrial ALDH1B1 Tbio Enzyme -1.73034 52.5 194
Fatty aldehyde dehydrogenase ALDH3A2 Tbio Enzyme -2.29743 197.2 311
Aldehyde dehydrogenase, mitochondrial ALDH2 Tclin Enzyme -2.97865 1004.9 470