Development Level

Tbio 171 | 11,651
Tchem 30 | 1,388
Tclin 19 | 612
Tdark 3 | 6,593

Collection

GPCR: IDG Consortium (Targets) 1 | 126
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 17 | 979
enlarged heart 8 | 210
decreased vertical activity 7 | 208
embryonic lethality prior to t... 7 | 278
abnormal heart morphology 5 | 162
increased total body fat amoun... 5 | 134
preweaning lethality, incomple... 5 | 499
decreased bone mineral content 4 | 151
decreased lean body mass 4 | 135
limb grasping 4 | 41
abnormal bone structure 3 | 187
cataract 3 | 92
decreased body weight 3 | 161
decreased fasted circulating g... 3 | 65
embryonic lethality prior to o... 3 | 239
impaired glucose tolerance 3 | 75
impaired pupillary reflex 3 | 26
improved glucose tolerance 3 | 79
increased circulating choleste... 3 | 66
increased lymphocyte cell numb... 3 | 32
increased mean corpuscular vol... 3 | 92
increased monocyte cell number 3 | 63
increased startle reflex 3 | 112
prolonged QT interval 3 | 38
prolonged ST segment 3 | 36
abnormal embryo size 2 | 220
abnormal eye morphology 2 | 68
abnormal kidney morphology 2 | 65
abnormal retinal vasculature m... 2 | 27
corneal opacity 2 | 32
decreased bone mineral density 2 | 126
decreased circulating creatini... 2 | 39
decreased startle reflex 2 | 75
edema 2 | 59
enlarged lymph nodes 2 | 37
hydrometra 2 | 53
hypoactivity 2 | 132
impaired righting response 2 | 26
increased bone mineral content 2 | 108
increased circulating HDL chol... 2 | 80
increased circulating iron lev... 2 | 30
increased circulating total pr... 2 | 28
increased circulating triglyce... 2 | 42
increased heart weight 2 | 62
increased leukocyte cell numbe... 2 | 47
increased neutrophil cell numb... 2 | 46
microphthalmia 2 | 26
short tibia 2 | 97
abnormal body wall morphology 1 | 9
abnormal brain morphology 1 | 13
abnormal cornea morphology 1 | 31
abnormal embryo development 1 | 7
abnormal embryo turning 1 | 31
abnormal gait 1 | 69
abnormal lens morphology 1 | 81
abnormal lung morphology 1 | 26
abnormal optic disc morphology 1 | 10
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
abnormal whole-body plethysmog... 1 | 4
absent startle reflex 1 | 24
cleft palate 1 | 8
convulsive seizures 1 | 13
decreased body length 1 | 101
decreased circulating amylase ... 1 | 28
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased heart rate 1 | 18
decreased hematocrit 1 | 46
decreased neutrophil cell numb... 1 | 42
female infertility 1 | 60
fused cornea and lens 1 | 5
hemorrhage 1 | 23
hydroencephaly 1 | 14
increased blood urea nitrogen ... 1 | 48
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating creatini... 1 | 38
increased circulating magnesiu... 1 | 10
increased circulating serum al... 1 | 22
increased fasted circulating g... 1 | 76
increased heart rate variabili... 1 | 7
increased large unstained cell... 1 | 5
increased mean platelet volume 1 | 45
iris synechia 1 | 3
narrow eye opening 1 | 12
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28
prolonged RR interval 1 | 8
small superior vagus ganglion 1 | 74
small testis 1 | 58
vertebral fusion 1 | 23

Disease

Cancer 117 | 2,499
Carcinoma 110 | 11,493
psoriasis 100 | 6,694
lung cancer 70 | 4,740
osteosarcoma 61 | 7,950
ovarian cancer 60 | 8,520
Schizophrenia 59 | 1,160
diabetes mellitus 59 | 1,728
glioblastoma 59 | 5,792
ependymoma 58 | 4,679
malignant mesothelioma 57 | 3,232
medulloblastoma, large-cell 53 | 6,241
atypical teratoid / rhabdoid tumor 50 | 5,112
Breast cancer 49 | 3,578
Astrocytoma, Pilocytic 46 | 3,081
group 3 medulloblastoma 46 | 4,104
lung carcinoma 45 | 2,843
interstitial cystitis 44 | 2,312
Obesity 43 | 678
Depressive disorder 42 | 409
Kidney disease 42 | 430
Asthma 41 | 385
Bipolar Disorder 39 | 666
Hypertension 39 | 396
adult high grade glioma 38 | 3,801
cystic fibrosis 38 | 1,696
oligodendroglioma 37 | 2,850
Autosomal recessive predisposition 36 | 1,442
Mental Depression 35 | 333
pituitary cancer 35 | 1,972
tuberculosis 34 | 2,010
ulcerative colitis 33 | 1,819
Alcoholic Intoxication, Chronic 32 | 289
Arthritis 32 | 290
lung adenocarcinoma 32 | 2,716
Major Depressive Disorder 31 | 301
invasive ductal carcinoma 31 | 2,951
non-small cell lung cancer 31 | 2,890
Liver Cirrhosis, Experimental 30 | 769
intraductal papillary-mucinous adenoma (IPMA) 30 | 2,955
Hypertensive disease 29 | 292
Osteoporosis 29 | 363
Autistic Disorder 28 | 364
Breast Neoplasms 28 | 445
Diarrhea 28 | 253
Heart disease 28 | 306
Inflammatory bowel disease 28 | 151
Mammary Neoplasms 28 | 425
Unipolar Depression 28 | 250
colon cancer 28 | 1,478
Anemia 27 | 365
Hypersensitivity reaction type II disease 27 | 253
Rheumatoid arthritis 27 | 1,191
astrocytic glioma 27 | 2,597
pancreatic cancer 27 | 2,398
Hypotension 26 | 82
Pulmonary Fibrosis 26 | 106
intraductal papillary-mucinous neoplasm (IPMN) 26 | 3,291
primitive neuroectodermal tumor 26 | 3,035
Cerebrovascular disease 25 | 238
Inflammation 25 | 120
Lung disease 25 | 142
Multiple Sclerosis 25 | 540
Seizures 25 | 596
Atherosclerosis 24 | 291
Parkinson's disease 24 | 392
Adenoma 23 | 167
Alzheimer's disease 23 | 658
Coronary artery disease 23 | 268
Mood Disorders 23 | 184
Endometriosis 22 | 540
Hypoglycemia 22 | 152
Pain 22 | 103
Polycystic ovary syndrome 22 | 360
Prostatic Neoplasms 22 | 495
Vascular disease 22 | 319
cutaneous lupus erythematosus 22 | 1,057
Allergic hypersensitivity disease 21 | 126
Hyperglycemia 21 | 137
Liver disease 21 | 237
Neuropathy 21 | 261
breast carcinoma 21 | 1,638
ductal carcinoma in situ 21 | 1,745
Cleft Palate 20 | 271
Infertility 20 | 188
Dermatitis 19 | 157
Hyperalgesia 19 | 83
Pancreatitis 19 | 123
Reperfusion Injury 19 | 86
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,989
Acromegaly 18 | 51
Epilepsy 18 | 792
Heart failure 18 | 162
Hypothyroidism 18 | 122
Abortion, Spontaneous 17 | 109
Allergic rhinitis 17 | 95
Liver carcinoma 17 | 240
Melanoma 17 | 711
Short stature 17 | 531
Spontaneous abortion 17 | 113

Tissue

Endocrine System 203 | 18,159
Female tissues 193 | 17,400
Digestive Tract 192 | 17,369
Skin and soft tissues 187 | 17,230
Blood and immune system 183 | 16,909
Nervous System 182 | 16,725
Male tissues 180 | 17,142
Liver and Pancreas 178 | 16,750
Urinary Tract 178 | 16,678
Respiratory system 174 | 16,393
Cardiovascular System 136 | 15,192

Target Family

Non-IDG 191 | 12,091
GPCR 31 | 408
Enzyme 1 | 4,145

PathwayCommons: inoh Pathway

http://pathwaycommons.org/pc2/... 223 | 223
http://pathwaycommons.org/pc2/... 236 | 236
http://pathwaycommons.org/pc2/... 235 | 235
http://pathwaycommons.org/pc2/... 233 | 233
http://pathwaycommons.org/pc2/... 224 | 224
http://pathwaycommons.org/pc2/... 224 | 224
http://pathwaycommons.org/pc2/... 223 | 223
http://pathwaycommons.org/pc2/... 183 | 183
http://pathwaycommons.org/pc2/... 178 | 178
http://pathwaycommons.org/pc2/... 173 | 173
http://pathwaycommons.org/pc2/... 173 | 173
http://pathwaycommons.org/pc2/... 123 | 123
http://pathwaycommons.org/pc2/... 96 | 96
http://pathwaycommons.org/pc2/... 85 | 85
http://pathwaycommons.org/pc2/... 63 | 63
http://pathwaycommons.org/pc2/... 60 | 60
http://pathwaycommons.org/pc2/... 58 | 58
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 56 | 56
http://pathwaycommons.org/pc2/... 55 | 55
http://pathwaycommons.org/pc2/... 51 | 51
http://pathwaycommons.org/pc2/... 49 | 49
http://pathwaycommons.org/pc2/... 48 | 48
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 47 | 47
http://pathwaycommons.org/pc2/... 45 | 45
http://pathwaycommons.org/pc2/... 44 | 44
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 43 | 43
http://pathwaycommons.org/pc2/... 42 | 42
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 40 | 40
http://pathwaycommons.org/pc2/... 38 | 38
http://pathwaycommons.org/pc2/... 37 | 37
http://pathwaycommons.org/pc2/... 36 | 36
http://pathwaycommons.org/pc2/... 36 | 36
http://pathwaycommons.org/pc2/... 35 | 35
http://pathwaycommons.org/pc2/... 35 | 35
http://pathwaycommons.org/pc2/... 35 | 35
http://pathwaycommons.org/pc2/... 34 | 34
http://pathwaycommons.org/pc2/... 30 | 30
http://pathwaycommons.org/pc2/... 30 | 30
http://pathwaycommons.org/pc2/... 29 | 29
http://pathwaycommons.org/pc2/... 29 | 29
http://pathwaycommons.org/pc2/... 28 | 28
http://pathwaycommons.org/pc2/... 27 | 27
http://pathwaycommons.org/pc2/... 27 | 27
http://pathwaycommons.org/pc2/... 24 | 24
http://pathwaycommons.org/pc2/... 24 | 24
http://pathwaycommons.org/pc2/... 24 | 24
http://pathwaycommons.org/pc2/... 24 | 24
http://pathwaycommons.org/pc2/... 24 | 24
http://pathwaycommons.org/pc2/... 24 | 24
http://pathwaycommons.org/pc2/... 22 | 22
http://pathwaycommons.org/pc2/... 21 | 21
http://pathwaycommons.org/pc2/... 21 | 21
http://pathwaycommons.org/pc2/... 21 | 21
http://pathwaycommons.org/pc2/... 21 | 21
http://pathwaycommons.org/pc2/... 20 | 20
http://pathwaycommons.org/pc2/... 20 | 20
http://pathwaycommons.org/pc2/... 20 | 20
http://pathwaycommons.org/pc2/... 20 | 20
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 18 | 18
http://pathwaycommons.org/pc2/... 18 | 18
http://pathwaycommons.org/pc2/... 18 | 18
http://pathwaycommons.org/pc2/... 18 | 18
http://pathwaycommons.org/pc2/... 18 | 18
http://pathwaycommons.org/pc2/... 18 | 18
http://pathwaycommons.org/pc2/... 18 | 18
http://pathwaycommons.org/pc2/... 17 | 17
http://pathwaycommons.org/pc2/... 17 | 17
http://pathwaycommons.org/pc2/... 17 | 17
http://pathwaycommons.org/pc2/... 17 | 17
http://pathwaycommons.org/pc2/... 17 | 17
http://pathwaycommons.org/pc2/... 16 | 16
http://pathwaycommons.org/pc2/... 16 | 16
http://pathwaycommons.org/pc2/... 16 | 16
http://pathwaycommons.org/pc2/... 16 | 16
http://pathwaycommons.org/pc2/... 16 | 16
http://pathwaycommons.org/pc2/... 16 | 16
http://pathwaycommons.org/pc2/... 15 | 15

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interleukin-9 IL9 Tbio Non-IDG -2.50811 334.4 459
Endothelin-1 EDN1 Tbio Non-IDG -4.07520 12851.9 607
Metabotropic glutamate receptor 2 GRM2 Tchem GPCR -2.77035 612.3 315
Interleukin-6 IL6 Tclin Non-IDG -4.50976 30968.8 2075
Bone morphogenetic protein 15 BMP15 Tbio Non-IDG -2.33917 221.7 200
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 GNB3 Tbio Non-IDG -2.34836 235.8 161
Alpha-taxilin TXLNA Tbio Non-IDG -1.08682 11.4 99
Transforming growth factor beta-1 TGFB1 Tchem Non-IDG -3.84680 5672.0 1222
Vasopressin-neurophysin 2-copeptin AVP Tbio Non-IDG -3.92570 8381.2 203
Protransforming growth factor alpha TGFA Tbio Non-IDG -2.15761 135.3 697