Development Level

Tbio 10 | 11,445
Tchem 6 | 1,598
Tclin 3 | 613

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal cecum morphology 1 | 7
abnormal lens morphology 1 | 81
decreased eosinophil cell numb... 1 | 24
decreased heart weight 1 | 27
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
embryonic lethality prior to t... 1 | 278
enlarged cecum 1 | 5
enlarged uterus 1 | 11
increased eosinophil cell numb... 1 | 11
increased fasted circulating g... 1 | 76
increased neutrophil cell numb... 1 | 46
small superior vagus ganglion 1 | 74

Disease

psoriasis 13 | 6,694
Carcinoma 11 | 11,493
glioblastoma 11 | 5,792
lung cancer 10 | 4,740
ovarian cancer 10 | 8,520
malignant mesothelioma 9 | 3,232
medulloblastoma, large-cell 9 | 6,241
Cancer 8 | 2,499
lung carcinoma 8 | 2,843
tuberculosis 8 | 2,010
Astrocytoma, Pilocytic 7 | 3,081
Rheumatoid arthritis 7 | 1,191
adult high grade glioma 7 | 3,801
dermatomyositis 7 | 966
osteosarcoma 7 | 7,950
Arthritis 6 | 290
atypical teratoid / rhabdoid tumor 6 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
juvenile dermatomyositis 6 | 1,187
subependymal giant cell astrocytoma 6 | 2,287
Asthma 5 | 385
Brain Injuries 5 | 65
Hypersensitivity reaction type II disease 5 | 253
Inflammatory bowel disease 5 | 151
Pneumonia 5 | 174
cutaneous lupus erythematosus 5 | 1,057
cystic fibrosis 5 | 1,696
diabetes mellitus 5 | 1,728
interstitial cystitis 5 | 2,312
oligodendroglioma 5 | 2,850
ulcerative colitis 5 | 1,819
Arthritis, Rheumatoid 4 | 174
Cholestasis, Extrahepatic 4 | 25
Coronary artery disease 4 | 268
Cryopyrin associated periodic syndrome 4 | 5
Diarrhea 4 | 253
Inflammation 4 | 120
Liver Cirrhosis, Experimental 4 | 769
Meningitis 4 | 67
Peritonitis 4 | 43
Reperfusion Injury 4 | 86
Schizophrenia 4 | 1,160
astrocytic glioma 4 | 2,597
ependymoma 4 | 4,679
group 4 medulloblastoma 4 | 1,855
non-small cell lung cancer 4 | 2,890
pancreatic cancer 4 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
periodontitis 4 | 293
Alcoholic Intoxication, Chronic 3 | 289
Allergic hypersensitivity disease 3 | 126
Breast cancer 3 | 3,578
Burns, Chemical 3 | 6
Cerebrovascular disease 3 | 238
Chemical and Drug Induced Liver Injury 3 | 195
Chorioamnionitis 3 | 14
Dermatitis 3 | 157
Dermatologic disorders 3 | 93
Duchenne muscular dystrophy 3 | 601
Endometriosis 3 | 540
Fever 3 | 138
Hypertension 3 | 396
Hypertensive disease 3 | 292
Influenza 3 | 142
Kidney disease 3 | 430
Liver disease 3 | 237
Lung disease 3 | 142
Malaria 3 | 160
Mastitis 3 | 48
Melioidosis 3 | 17
Multiple Sclerosis 3 | 540
Neoplasm Invasiveness 3 | 161
Obesity 3 | 678
Osteoporosis 3 | 363
Perinatal necrotizing enterocolitis 3 | 21
Pick disease 3 | 1,894
Prostatic Neoplasms 3 | 495
Salmonellosis 3 | 42
Skin Diseases 3 | 71
acute quadriplegic myopathy 3 | 1,158
adrenocortical carcinoma 3 | 1,428
aldosterone-producing adenoma 3 | 665
astrocytoma 3 | 1,146
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
lung adenocarcinoma 3 | 2,716
pituitary cancer 3 | 1,972
Atherosclerosis 2 | 291
Brain Ischemia 2 | 110
Cholestasis 2 | 155
Disease Progression 2 | 136
Eye disease 2 | 62
Heart disease 2 | 306
Leishmaniasis 2 | 47
Lung Neoplasms 2 | 232
Parasitic helminthiasis infectious disease 2 | 15
Type 2 diabetes mellitus 2 | 272
Vasculitis 2 | 80
active ulcerative colitis 2 | 764
pediatric high grade glioma 2 | 1,064

Tissue

Blood and immune system 19 | 16,909
Digestive Tract 19 | 17,369
Endocrine System 19 | 18,159
Female tissues 19 | 17,400
Liver and Pancreas 19 | 16,750
Male tissues 19 | 17,142
Nervous System 19 | 16,725
Skin and soft tissues 19 | 17,230
Urinary Tract 19 | 16,678
Respiratory system 18 | 16,393
Cardiovascular System 17 | 15,192

Target Family

Non-IDG 14 | 12,091
Kinase 4 | 634
Enzyme 1 | 4,145

PathwayCommons: inoh Pathway

http://pathwaycommons.org/pc2/... 19 | 19
http://pathwaycommons.org/pc2/... 236 | 236
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This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ubiquitin-conjugating enzyme E2 variant 1 UBE2V1 Tbio Non-IDG -1.33153 18.0 188
Lymphocyte antigen 96 LY96 Tchem Non-IDG -2.77678 541.2 369
Lipopolysaccharide-binding protein LBP Tbio Non-IDG -2.61682 357.2 225
TNF receptor-associated factor 6 TRAF6 Tbio Non-IDG -2.74221 511.1 403
Myeloid differentiation primary response protein MyD88 MYD88 Tbio Non-IDG -3.26747 1795.4 672
Interleukin-1 receptor-associated kinase 4 IRAK4 Tchem Kinase -2.28820 202.2 610
Ubiquitin-conjugating enzyme E2 N UBE2N Tbio Non-IDG -2.08846 107.8 268
Interleukin-1 beta IL1B Tclin Non-IDG -4.40738 24522.4 1588
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TAB2 Tbio Enzyme -1.90517 75.2 151
Mitogen-activated protein kinase kinase kinase 7 MAP3K7 Tchem Kinase -1.46817 32.4 765